(Q40446144)

English

The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint (English)

1 reference

Europe PubMed Central

20 September 2017

author name string

Ying Wai Chan

1

1 reference

Europe PubMed Central

20 September 2017

Kin Fan On

2

1 reference

Europe PubMed Central

20 September 2017

Wan Mui Chan

3

1 reference

Europe PubMed Central

20 September 2017

Winnie Wong

4

1 reference

Europe PubMed Central

20 September 2017

Ho On Siu

5

1 reference

Europe PubMed Central

20 September 2017

Pok Man Hau

6

1 reference

Europe PubMed Central

20 September 2017

Randy Y C Poon

7

1 reference

Europe PubMed Central

20 September 2017

language of work or name

0 references

publication date

9 April 2008

1 reference

Europe PubMed Central

20 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

20 September 2017

283

1 reference

Europe PubMed Central

20 September 2017

23

1 reference

Europe PubMed Central

20 September 2017

15716-15723

1 reference

Europe PubMed Central

20 September 2017

Limiting the proliferation of polyploid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

The spindle-assembly checkpoint in space and time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Tetraploidy, aneuploidy and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization

1 reference

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22 September 2017

Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

1 reference

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22 September 2017

Apoptosis regulation in tetraploid cancer cells

1 reference

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22 September 2017

A primate virus generates transformed human cells by fusion

1 reference

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22 September 2017

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

1 reference

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22 September 2017

Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

1 reference

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22 September 2017

On the road to cancer: aneuploidy and the mitotic checkpoint

1 reference

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22 September 2017

Establishment of a doxycycline-regulated cell line with inducible, doubly-stable expression of the wild-type p53 gene from p53-deleted hepatocellular carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation

1 reference

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22 September 2017

Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

How many mutant p53 molecules are needed to inactivate a tetramer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Identification of a MAD2-binding protein, CMT2, and its role in mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Cyclin F is degraded during G2-M by mechanisms fundamentally different from other cyclins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

BUBR1 phosphorylation is regulated during mitotic checkpoint activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

22 September 2017

p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

25 September 2017

On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

25 September 2017

p53 does not control the spindle assembly cell cycle checkpoint but mediates G1 arrest in response to disruption of microtubule system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

25 September 2017

Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

15 June 2018

Differential responses of proliferating versus quiescent cells to adriamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

15 June 2018

p53-independent abrogation of a postmitotic checkpoint contributes to human papillomavirus E6-induced polyploidy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

20 August 2018

Sustained mitotic block elicits DNA breaks: one-step alteration of ploidy and chromosome integrity in mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

20 August 2018

The significance of unstable chromosomes in colorectal cancer.

1 reference

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20 August 2018

p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

20 August 2018

p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

20 August 2018

DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259627

20 August 2018

A p53-dependent mouse spindle checkpoint

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800629200

21 January 2018

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18400748

12 December 2020

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Identifiers

10.1074/JBC.M800629200

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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