(Q40458245)

20 September 2017

title

Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim. (English)

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20 September 2017

1 reference

R Li

1

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20 September 2017

T Moudgil

series ordinal

2

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20 September 2017

H J Ross

series ordinal

3

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20 September 2017

H-M Hu

series ordinal

4

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20 September 2017

publication date

1 March 2005

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Cell Death & Differentiation

20 September 2017

published in

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20 September 2017

volume

12

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20 September 2017

issue

3

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20 September 2017

page(s)

292-303

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Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxol- or 2-methoxyestradiol-induced apoptosis

20 September 2017

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Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells

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Mitochondria and apoptosis

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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Cell death regulation by the Bcl-2 protein family in the mitochondria

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Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

21 January 2018

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Bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

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Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis

21 January 2018

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Involvement of mitochondrial pathway in Taxol-induced apoptosis of human T24 bladder cancer cells

21 January 2018

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A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines

21 January 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

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Paclitaxel-induced cell death: where the cell cycle and apoptosis come together

21 January 2018

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Mitotic checkpoints: from yeast to cancer

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AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

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Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers

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Taxol-induced apoptosis in human SKOV3 ovarian and MCF7 breast carcinoma cells is caspase-3 and caspase-9 independent

21 January 2018

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Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

21 January 2018

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Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

21 January 2018

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Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

21 January 2018

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Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity

21 January 2018

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Defective caspase-3 relocalization in non-small cell lung carcinoma.

21 January 2018

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Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment

21 January 2018

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Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.

21 January 2018

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BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

21 January 2018

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Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

21 January 2018

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Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway

21 January 2018

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A p34(cdc2) survival checkpoint in cancer

21 January 2018

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The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

21 January 2018

1 reference

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

21 January 2018

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Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

21 January 2018

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Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

21 January 2018

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Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

p38 Mitogen-activated protein kinase mediates cell death and p21-activated kinase mediates cell survival during chemotherapeutic drug-induced mitotic arrest

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Targeting and amplification of immune killing of tumor cells by pro-Smac

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

7 January 2021

Pro-apoptotic BH3-only Bcl-2 family members in vertebrate model organisms suitable for genetic experimentation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

7 January 2021

Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

7 January 2021

Hypoxia induces the expression of the pro-apoptotic gene BNIP3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

7 January 2021

Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401554

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401554

1 reference

Dimensions Publication ID

20 September 2017

1050589146

0 references

1 reference