(Q40458251)

English

The immunosuppressive drugs cyclosporin A and tacrolimus inhibit membrane depolarization-induced CREB transcriptional activity at the coactivator level

scientific article published on April 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

The immunosuppressive drugs cyclosporin A and tacrolimus inhibit membrane depolarization-induced CREB transcriptional activity at the coactivator level (English)

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

1 reference

ChEBI release 2020-05-28

author name string

Elke Oetjen

1

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Kai-Martin Thoms

2

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Yvonne Laufer

3

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Daniela Pape

4

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Roland Blume

5

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Pingfeng Li

6

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Willhart Knepel

7

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

language of work or name

0 references

publication date

1 April 2005

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

144

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

982-993

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Regulation of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus at concentrations that inhibit calcineurin activity and involving the transcription factor CREB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Disruption of CREB function in brain leads to neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Transcriptional regulation by the phosphorylation-dependent factor CREB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

T cell activation signals upregulate CBP-dependent transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Transcription factor-specific requirements for coactivators and their acetyltransferase functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

RNA helicase A mediates association of CBP with RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Phosphorylated CREB binds specifically to the nuclear protein CBP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Nuclear protein CBP is a coactivator for the transcription factor CREB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

cAMP-dependent regulation of gene transcription by cAMP response element-binding protein and cAMP response element modulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

A vector for expressing GAL4(1-147) fusions in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

22 September 2017

Regulation of insulin gene transcription by a Ca(2+)-responsive pathway involving calcineurin and nuclear factor of activated T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

The acetyltransferase activity of CBP stimulates transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

Differential use of CREB binding protein-coactivator complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

The mechanism of action of cyclosporin A and FK506.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

An inactivating point mutation demonstrates that interaction of cAMP response element binding protein (CREB) with the CREB binding protein is not sufficient for transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

Involvement of the Ca(2+)-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

25 September 2017

Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

15 June 2018

Inhibition of human insulin gene transcription by the immunosuppressive drugs cyclosporin A and tacrolimus in primary, mature islets of transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

20 August 2018

Phosphorylation of CREB Ser142 regulates light-induced phase shifts of the circadian clock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

20 August 2018

Phosphorylation of CBP mediates transcriptional activation by neural activity and CaM kinase IV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

20 August 2018

Inhibition of cyclic AMP response element-binding protein/cyclic AMP response element-mediated transcription by the immunosuppressive drugs cyclosporin A and FK506 depends on the promoter context.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576078

20 August 2018

Regulation of CBP-mediated transcription by neuronal calcium signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15711594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element

1 reference

https://pubmed.ncbi.nlm.nih.gov/15711594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15711594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB

1 reference

https://pubmed.ncbi.nlm.nih.gov/15711594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of CREB- and cAMP response element-mediated gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15711594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0706127

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

ResearchGate publication ID

0 references

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