(Q40462593)

20 September 2017

Inactivation of ErbB3 by siRNA promotes apoptosis and attenuates growth and invasiveness of human lung adenocarcinoma cell line A549. (English)

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20 September 2017

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neoplastic invasiveness

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Gunamani Sithanandam

1

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20 September 2017

Laura W Fornwald

series ordinal

2

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20 September 2017

Janet Fields

series ordinal

3

1 reference

20 September 2017

Lucy M Anderson

series ordinal

4

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20 September 2017

language of work or name

English

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publication date

1 March 2005

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20 September 2017

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20 September 2017

24

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20 September 2017

1847-1859

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20 September 2017

11

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208381

20 September 2017

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cites work

Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

A portrait of AKT kinases: human cancer and animal models depict a family with strong individualities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Regulation of Akt/PKB activation by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

The deaf and the dumb: the biology of ErbB-2 and ErbB-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Lung cancer screening using low-dose high-resolution CT scanning in a high-risk workforce: 3500 nuclear fuel workers in three US states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Autocrine activation of ErbB2/ErbB3 receptor complex by NRG-1 in non-small cell lung cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Immunohistochemical typing of non-small cell lung cancer on cryostat sections: correlation with clinical parameters and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Downregulation of Akt1 inhibits anchorage-independent cell growth and induces apoptosis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Epidermal growth factor receptor-targeted therapy with ZD1839: symptom improvement in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Neuregulin-1 and human epidermal growth factor receptors 2 and 3 play a role in human lung development in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Production and characterization of a polyclonal antibody to the c-erbB-3 protein: examination of c-erbB-3 protein expression in adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Targeted therapies for non-small-cell lung cancer: biology, rationale, and preclinical results from a radiation oncology perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Neuregulin-1 enhances motility and migration of human astrocytic glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Enhanced stimulation of Akt-3/protein kinase B-gamma in human aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Nuclear factor-kappaB: a friend or a foe in cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Epidermal growth factor receptors in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Roles of mitogen-activated protein kinase and phosphoinositide 3'-kinase in ErbB2/ErbB3 coreceptor-mediated heregulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Apigenin Induces Apoptosis through Proteasomal Degradation of HER2/neu in HER2/neu-overexpressing Breast Cancer Cells via the Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 3'-kinase/Akt pathway in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Untangling the ErbB signalling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Akt phosphorylation and NFκB activation are counterregulated under conditions of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Prognostic value of c-erbB-2 protein expression in human lung adenocarcinoma and squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

Immunohistochemical analysis of epidermal growth factor receptor family members in stage I non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

inferred from DOI database lookup

7 January 2021

based on heuristic

Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208381

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1208381

1 reference

Dimensions Publication ID

20 September 2017

0 references

1 reference