(Q40463544)

20 September 2017

1 reference

title

The Role of Covalent Binding to Microsomal Proteins in the Hepatotoxicity of Acetaminophen (English)

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

7 July 2024

1 reference

J. L. Holtzman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7641580

7 July 2024

language of work or name

English

0 references

publication date

1 January 1995

1 reference

full work available at URL

20 September 2017

http://www.tandfonline.com/doi/pdf/10.3109/03602539509029827

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

7 July 2024

published in

Drug Metabolism Reviews

1 reference

20 September 2017

volume

27

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20 September 2017

issue

1-2

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20 September 2017

page(s)

277-297

1 reference

Covalent binding of [14C]methoxychlor metabolite(s) to rat liver microsomal components.

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F03602539509029827

N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

21 January 2018

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Effects of ethanol and inhibitors on the binding and metabolism of acetaminophen and N-acetyl-p-benzoquinone imine by hepatic microsomes from control and ethanol-treated rats

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539509029827

Purification, antibody production, and partial amino acid sequence of the 58-kDa acetaminophen-binding liver proteins

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539509029827

A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein

21 January 2018

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Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539509029827

Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539509029827

A metabolite of halothane covalently binds to an endoplasmic reticulum protein that is highly homologous to phosphatidylinositol-specific phospholipase C-alpha but has no activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539509029827

The calcium-binding protein calreticulin is covalently modified in rat liver by a reactive metabolite of the inhalation anesthetic halothane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539509029827

In Vivo Effect of Uncoupling Agents on the Incorporation of Calcium and Strontium into Mitochondria and Other Subcellular Fractions of Rat Liver

21 January 2018

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The role of calcium in lethal cell injury

21 January 2018

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Immediate rise in intracellular calcium and glycogen phosphorylase a activities upon acetaminophen covalent binding leading to hepatotoxicity in mice

21 January 2018

1 reference

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Molecular chaperone functions of heat-shock proteins

21 January 2018

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Cell physiology: Cellular site of calcium regulation

21 January 2018

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Calcium content of mitochondria and endoplasmic reticulum in liver frozen rapidly in vivo

21 January 2018

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History of drug metabolism: the first half of the 20th century

21 January 2018

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Metabolic products of naphthalene in mammalian systems

7 July 2024

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1,2-Naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. V

7 July 2024

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Journal of Pharmacology and Experimental Therapeutics

7 July 2024

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Bromobenzene and p-bromophenol toxicity and covalent binding in vivo

7 July 2024

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Hepatotoxicity after 3'-hydroxyacetanilide administration to buthionine sulfoximine-pretreated mice

7 July 2024

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Role of glutathione depletion in the cytotoxicity of acetaminophen in a primary culture system of rat hepatocytes

7 July 2024

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7 July 2024

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7 July 2024

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7 July 2024

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Hinson J. A.

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N-hydroxyacetaminophen: A microsomal metabolite of N-hydroxyphenacetin but apparently not of acetaminophen

7 July 2024

14

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Journal of Pharmacology and Experimental Therapeutics

7 July 2024

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7 July 2024

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7 July 2024

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Clinical Features of Acetaminophen Toxicity

7 July 2024

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Effect of chronic ethanol administration on drug metabolism in isolated hepatocytes with emphasis on paracetamol activation

7 July 2024

26

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Studies on the effect of chronic consumption of moderate amounts of ethanol on male rat hepatic microsomal drug-metabolizing activity

7 July 2024

27

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics

7 July 2024

28

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Analysis of acetaminophen metabolites in urine by high-performance liquid chromatography with UV and amperometric detection

7 July 2024

29

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Potentiation of acute acetaminophen lethality by selenium and vitamin E deficiency in mice

7 July 2024

30

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

The arylation of microsomal membrane proteins by acetaminophen is associated with the release of a 44 kDa acetaminophen-binding mouse liver protein complex into the cytosol

7 July 2024

31

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Immunochemical detection of acetaminophen-bound liver proteins

7 July 2024

34

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Toxicology and Applied Pharmacology

7 July 2024

35

105

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Birge R. B.

1987

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Hapten carrier conjugates associated with halothane hepatitis

7 July 2024

41

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

The high-affinity calcium binding protein of sarcoplasmic reticulum. Tissue distribution, and homology with calregulin

7 July 2024

48

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Interactions between N-acetyl-p-benzoquinone imine and fluorescent calcium probes: implications for mechanistic toxicology

7 July 2024

61

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Implication of alterations in intracellular calcium ion homoeostasis in the advent of paracetamol-induced cytotoxicity in primary mouse hepatocyte monolayer cultures

7 July 2024

64

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

Paracetamol toxicity in hamster isolated hepatocytes: the increase in cytosolic calcium accompanies, rather than precedes, loss of viability

7 July 2024

65

1 reference

https://api.crossref.org/works/10.3109/03602539509029827

7 July 2024

Identifiers

1 reference

20 September 2017

1 reference