(Q40465098)

20 September 2017

1 reference

title

Genotoxicity, carcinogenicity and acid-suppressing medications (English)

1 reference

https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

10 July 2024

1 reference

R. E. Powers

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7644566

10 July 2024

G. P. Lawton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7644566

10 July 2024

I. M. Modlin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7644566

10 July 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7644566

10 July 2024

publication date

1 March 1995

1 reference

full work available at URL

20 September 2017

https://api.elsevier.com/content/article/PII:016372589598596I?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

https://api.elsevier.com/content/article/PII:016372589598596I?httpAccept=text/plain

10 July 2024

1 reference

https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

Pharmacology & Therapeutics

10 July 2024

published in

1 reference

20 September 2017

volume

65

1 reference

20 September 2017

issue

3

1 reference

20 September 2017

page(s)

303-317

1 reference

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

20 September 2017

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Prediction of non-genotoxic carcinogenesis

10 July 2024

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Enhanced hyperplasia of gastric enterochromaffinlike cells in response to omeprazole-evoked hypergastrinemia in rats with portacaval shunts. An immunocytochemical and chemical study

10 July 2024

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H2-receptor blockade induces peptide YY and enteroglucagon-secreting gastric carcinoids in mastomys

10 July 2024

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Atrophic gastritis and gastric carcinoid tumours.

10 July 2024

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Gastric endocrine cell hyperplasia and carcinoid tumors in pernicious anemia

10 July 2024

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Genotoxic effects in rodents given high oral doses of ranitidine and sodium nitrite

10 July 2024

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Evolution of testing strategies for genetic toxicity

10 July 2024

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An in vivo unscheduled DNA synthesis (UDS) assay in the rat gastric mucosa: preliminary development.

10 July 2024

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Uptake of tritiated thymidine by cells of the rat gastric mucosa after exposure to loxtidine or omeprazole

10 July 2024

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Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors

10 July 2024

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Levels of direct-acting mutagens, total N-nitroso compounds in nitrosated fermented fish products, consumed in a high-risk area for gastric cancer in southern China

10 July 2024

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8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions

10 July 2024

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Metastatic potential of mouse skin carcinomas produced by different protocols of chemical carcinogenesis

10 July 2024

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Early indicators of potential neoplasia produced in the rat forestomach by non-genotoxic agents: the importance of induced cellular proliferation

10 July 2024

15

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Covalent binding of 1,1,1,2‐tetrachloroethane to nucleic acids as evidence of genotoxic activity

10 July 2024

16

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The gastric microenvironment in populations at high risk to stomach cancer

10 July 2024

17

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Induction of gastrointestinal tract nuclear anomalies in B6C3F1 mice by 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and 3,4-(dichloro)-5-hydroxy-2[5H]-furanone, mutagenic byproducts of chlorine disinfection

10 July 2024

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The initiation-promotion-progression model of rat hepatocarcinogenesis

10 July 2024

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Toxicological studies on omeprazole

10 July 2024

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A modified mouse peripheral blood lymphocyte culture system for cytogenetic analysis

10 July 2024

23

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Analyses of sister-chromatid exchange and cell-cycle kinetics in mouse T- and B-lymphocytes from peripheral blood cultures

10 July 2024

24

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Direct involvement of human gastric mucosa in the activation of alimentary pro-carcinogens

10 July 2024

25

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Mechanisms of chemical carcinogenesis: recent advances

10 July 2024

26

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The Expression of Mouse Tyrosinase in Chick Cells In Vitro and In Vivo When Controlled by a Constitutive Promoter

10 July 2024

27

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https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

Use of in vivo/in vitro unscheduled DNA synthesis for identification of organ-specific carcinogens

10 July 2024

28

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Genotoxicity and cell proliferative activity of omeprazole in rat stomach mucosa

10 July 2024

29

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Investigations into the genotoxic potential of loxtidine, a long-acting H2-receptor antagonist.

10 July 2024

30

1 reference

https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

In vitro mispairing specificity of O2-ethylthymidine

10 July 2024

31

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Mutagenesis by N-nitroso compounds: relationships to DNA adducts, DNA repair, and mutational efficiencies.

10 July 2024

32

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Gastrin and the trophic control of gastric mucosa.

10 July 2024

34

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Propionic acid and the phenomenon of rodent forestomach tumorigenesis: a review

10 July 2024

35

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Target sequences for mutagenesis in Salmonella histidine-requiring mutants.

10 July 2024

36

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Enterochromaffin-like cell carcinoids of gastric mucosa in rats after life-long inhibition of gastric secretion

10 July 2024

37

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Critical aspects of initiation, promotion, and progression in multistage epidermal carcinogenesis

10 July 2024

38

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Antisecretory therapy and genotoxicity

10 July 2024

39

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Observations on a proposed measure of genotoxicity in rat gastric mucosa

10 July 2024

40

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In vitro mammalian mutagenesis as a model for genetic lesions in human cancer

10 July 2024

41

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Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair.

10 July 2024

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DNA chain growth during replication of asynchronous L1210 cells. Alkaline elution of large DNA segments from cells lysed on filters

10 July 2024

43

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Fractionation of DNA from mammalian cells by alkaline elution

10 July 2024

44

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Forestomach carcinogens: possible mechanisms of action

10 July 2024

45

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Long-term omeprazole therapy in peptic ulcer disease: gastrin, endocrine cell growth, and gastritis.

10 July 2024

46

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Plasma gastrin and gastric enterochromaffinlike cell activation and proliferation. Studies with omeprazole and ranitidine in intact and antrectomized rats

10 July 2024

47

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Partial pronase digestion of rat gastric mucosa isolates cells undergoing replicative DNA synthesis

10 July 2024

48

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Cost-effectiveness of short-term tests for carcinogenicity.

10 July 2024

49

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Investigations into the reported ability of cimetidine to initiate UDS in rat hepatocyte primary cultures

10 July 2024

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Oncogenes and tumor-suppressor genes

10 July 2024

51

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Tumor suppressor genes: the p53 and retinoblastoma sensitivity genes and gene products

10 July 2024

52

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Omeprazole: the first proton pump inhibitor

10 July 2024

53

1 reference

https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

Ability of short-term tests to predict carcinogenesis in rodents

10 July 2024

54

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Unscheduled DNA synthesis tests. A report of the U.S. Environmental Protection Agency Gene-Tox Program

10 July 2024

55

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https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

Characteristics of the spontaneous gastric endocrine tumor of mastomys

10 July 2024

56

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Carcinogenesis Models: An Overview

10 July 2024

58

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Advantages of a combined testing protocol (CTP) with multiple endpoints: the reverse tier approach

10 July 2024

59

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Effect of histamine H2-receptor antagonist therapy on the mutagenic activity of gastric juice

10 July 2024

61

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Molecular and cellular basis for adequate metabolic design of genotoxicity studies

10 July 2024

62

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Scientific and cost-effectiveness criteria in selecting batteries of short-term tests

10 July 2024

63

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Formation of direct-acting genotoxic substances in nitrosated smoked fish and meat products: identification of simple phenolic precursors and phenyldiazonium ions as reactive products

10 July 2024

64

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https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

Non-genotoxic factors in the carcinogenetic process: problems of detection and hazard evaluation

10 July 2024

65

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https://api.crossref.org/works/10.1016/0163-7258(95)98596-I

The genotoxic/epigenetic distinction: Relevance to cancer policy

10 July 2024

66

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Interaction of omeprazole with DNA in rat tissues

10 July 2024

67

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DNA damage in stomach, kidney, liver and lung of rats treated with atrazine

10 July 2024

68

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Facts and theories concerning the mechanisms of carcinogenesis

10 July 2024

69

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Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat

10 July 2024

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Organ specific genotoxicity and carcinogenicity

10 July 2024

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Mammalian in vivo and in vitro cytogenetic assays: a report of the U.S. EPA's gene-tox program

10 July 2024

73

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Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens

10 July 2024

74

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Is the initial event in carcinogenesis an enhancement of the mutation rate?

10 July 2024

75

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The split-end model for homologous recombination at double-strand breaks and at Chi.

10 July 2024

76

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Omeprazole: an exploration of its reported genotoxicity

10 July 2024

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Trophic effects of continuous infusion of [Leu15]-gastrin-17 in the rat

10 July 2024

78

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Effects of partial resection of acid-secreting mucosa on plasma gastrin and enterochromaffin-like cells in the rat stomach

10 July 2024

79

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Gastrin stimulates the self-replication rate of enterochromaffinlike cells in the rat stomach. Effects of omeprazole, ranitidine, and gastrin-17 in intact and antrectomized rats

10 July 2024

80

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Cell digestion and genotoxicity assessment in gastric mucosa

10 July 2024

81

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Omeprazole and the gastric mucosa

10 July 2024

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Cell isolation and genotoxicity assessment in gastric mucosa

10 July 2024

84

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DNA sequence dependence of guanine-O6 alkylation by the N-nitroso carcinogens N-methyl- and N-ethyl-N-nitrosourea.

10 July 2024

85

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Frequent activation of the lck gene by promoter insertion and aberrant splicing in murine leukemia virus-induced rat lymphomas

10 July 2024

86

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Gastric cancer risk in chronic atrophic gastritis: statistical calculations of cross-sectional data

10 July 2024

87

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Qualitative Studies of Gastric Endocrine Cells in Patients Treated Long-term with Omeprazole

10 July 2024

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Evaluation of nongenotoxic and genotoxic factors modulating the frequency of micronucleated erythrocytes in the peripheral blood of mice.

10 July 2024

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Role of the benzoyloxyl radical in DNA damage mediated by benzoyl peroxide

10 July 2024

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Genotoxicity and cell proliferative activity of a nitrosated Oroxylum indicum Vent fraction in the pyloric mucosa of rat stomach

10 July 2024

92

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Histochemical and proliferative changes preceding the onset of spontaneous gastric adenocarcinoma in Mastomys natalensis

10 July 2024

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p53 from basic research to clinical applications

10 July 2024

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Tritiated thymidine incorporation into DNA in rat gastric mucosal cells

10 July 2024

96

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Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control

10 July 2024

98

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Application of a cellular test battery in the decision point approach to carcinogen identification

10 July 2024

100

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Methods for evaluating chemical genotoxicity

10 July 2024

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DNA synthesis and genotoxicity

10 July 2024

102

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Tumor enhancers: underestimated factors in the epidemiology of lifestyle-associated cancers

10 July 2024

103

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Strategies for the use of genetic toxicity tests

10 July 2024

104

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10 July 2024

Identifiers

1 reference

20 September 2017

1 reference