(Q40468378)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15661745%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site (English)

1 reference

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7 January 2020

1 reference

8

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7 January 2020

Trent M. Woodruff

3

1 reference

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7 January 2020

Joel D. A. Tyndall

6

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7 January 2020

Peter N. Monk

9

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7 January 2020

author name string

Adrian Higginbottom

1

1 reference

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7 January 2020

Stuart A Cain

2

1 reference

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7 January 2020

Lavinia M Proctor

4

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7 January 2020

Praveen K Madala

5

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7 January 2020

Stephen M Taylor

7

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7 January 2020

language of work or name

English

0 references

publication date

20 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15661745%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

7 January 2020

published in

1 reference

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7 January 2020

volume

280

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7 January 2020

issue

18

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7 January 2020

page(s)

17831-17840

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An activation switch in the ligand binding pocket of the C5a receptor

7 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Anaphylatoxins and infectious and non-infectious inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Anaphylatoxin inactivator of human plasma: its isolation and characterization as a carboxypeptidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

The pharmacophore of the human C5a anaphylatoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

The chemotactic receptor for human C5a anaphylatoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Response-selective C5a agonists: differential effects on neutropenia and hypotension in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Pharmacological characterization of antagonists of the C5a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Mutation of glutamate 199 of the human C5a receptor defines a binding site for ligand distinct from the receptor N terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

The influence of Lys68 in decepeptide agonists of C5a on C5a receptor binding, activation and selectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Relationships between structures and activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Characterisation of C5a receptor agonists from phage display libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Selection of novel ligands from a whole-molecule randomly mutated C5a library

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Analysis of receptor/ligand interactions using whole-molecule randomly-mutated ligand libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Crystal structure of rhodopsin: A G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

Small molecular probes for G-protein-coupled C5a receptors: conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410797200

21 January 2018

Identifiers

DOI

10.1074/JBC.M410797200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15661745%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference