(Q40470278)

20 September 2017

title

Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells. (English)

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20 September 2017

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Hongbin Li

1

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20 September 2017

Xiaoqin Ye

2

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20 September 2017

Chitladda Mahanivong

3

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20 September 2017

Dafang Bian

4

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20 September 2017

Jerold Chun

5

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20 September 2017

Shuang Huang

6

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20 September 2017

language of work or name

English

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publication date

14 January 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

11

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20 September 2017

page(s)

10564-10571

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Lysophosphatidic acid: mitogen and motility factor

20 September 2017

cites work

1 reference

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Lysophosphatidic acid is a bioactive mediator in ovarian cancer

21 January 2018

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Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells

21 January 2018

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Lysophosphatidic acid receptor-selective effects on Jurkat T cell migration through a Matrigel model basement membrane

21 January 2018

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Lysophospholipids increase interleukin-8 expression in ovarian cancer cells

21 January 2018

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Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior

21 January 2018

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Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2).

21 January 2018

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Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer

21 January 2018

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Plasminogen fragmentation and increased production of extracellular matrix-degrading proteinases are associated with serous epithelial ovarian cancer progression

21 January 2018

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Urokinase induces proliferation of human ovarian cancer cells: characterization of structural elements required for growth factor function

21 January 2018

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Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin

21 January 2018

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Suppression of urokinase expression and invasiveness by urinary trypsin inhibitor is mediated through inhibition of protein kinase C- and MEK/ERK/c-Jun-dependent signaling pathways

21 January 2018

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Antisense inhibition of urokinase reduces spread of human ovarian cancer in mice

21 January 2018

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High-affinity urokinase-derived cyclic peptides inhibiting urokinase/urokinase receptor-interaction: effects on tumor growth and spread

21 January 2018

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Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin

21 January 2018

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Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase

21 January 2018

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Lysophosphatidic Acid Stimulates Ovarian Cancer Cell Migration via a Ras-MEK Kinase 1 Pathway

21 January 2018

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Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells

21 January 2018

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Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

21 January 2018

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Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38alpha mitogen-activated protein kinase activity

21 January 2018

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Chemoattractant-stimulated NF-kappaB activation is dependent on the low molecular weight GTPase RhoA.

21 January 2018

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Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

21 January 2018

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Simultaneous up-regulation of urokinase-type plasminogen activator (uPA) and uPA receptor by hepatocyte growth factor/scatter factor in human glioma cells.

21 January 2018

1 reference

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Activation of the urokinase plasminogen activator/urokinase plasminogen activator receptor system and redistribution of E-cadherin are associated with hepatocyte growth factor-induced motility of pancreas tumor cells overexpressing Met.

21 January 2018

1 reference

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Co-localization of urokinase and its receptor on established human umbilical vein endothelial cell

21 January 2018

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NF-kappa B-mediated regulation of urokinase gene expression by PMA and TNF-alpha in human A549 cells

21 January 2018

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The ins and outs of lysophosphatidic acid signaling.

21 January 2018

1 reference

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Cooperation of Gq, Gi, and G12/13 in protein kinase D activation and phosphorylation induced by lysophosphatidic acid

21 January 2018

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Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists

21 January 2018

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New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

21 January 2018

1 reference

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Involvement of a mitogen-activated protein kinase signaling pathway in the regulation of urokinase promoter activity by c-Ha-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Insulin Activates Nuclear Factor κB in Mammalian Cells through a Raf-1-mediated Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Raf-1 protein kinase activates the NF-kappa B transcription factor by dissociating the cytoplasmic NF-kappa B-I kappa B complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Molecular aspects of tumor cell invasion and metastasis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412152200

Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis

21 January 2018

1 reference

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Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Lysophosphatidic acid as a novel cell survival/apoptotic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

ralGDS family members interact with the effector loop of ras p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Rel transcription factors contribute to elevated urokinase expression in human ovarian carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

Membrane proteases in focus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412152200

21 January 2018

Identifiers

DOI

10.1074/JBC.M412152200

1 reference

20 September 2017

1 reference