(Q40472033)

20 September 2017

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title

Clinical pharmacokinetics of tacrine. (English)

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20 September 2017

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S Madden

1

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20 September 2017

V Spaldin

series ordinal

2

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20 September 2017

B K Park

series ordinal

3

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20 September 2017

1 June 1995

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Clinical Pharmacokinetics

20 September 2017

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20 September 2017

28

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20 September 2017

6

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20 September 2017

449-457

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https://scigraph.springernature.com/pub.10.2165/00003088-199528060-00003

20 September 2017

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cites work

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Stereoselective hydroxylation of tacrine in rats and humans

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Disposition of propranolol. V. Drug accumulation and steady-state concentrations during chronic oral administration in man.

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12 December 2020

Tacrine in Alzheimer's disease

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The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes

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Characterisation of theophylline metabolism by human liver microsomes. Inhibition and immunochemical studies

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12 December 2020

Treatment for Alzheimer's disease?

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12 December 2020

Comparison of the chromatographic characteristics of metabolites of tacrine hydrochloride in human serum and urine with those of in vitro metabolic products from hepatic microsomes

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Some aspects of the pharmacology of morphine with special reference to its antagonism by 5-amino-acridine and other chemically related compounds

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Alzheimer's drug trial put on hold.

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Distribution of tacrine across the blood-brain barrier in awake, freely moving rats using in vivo microdialysis sampling.

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Identification of 9-hydroxylamine-1,2,3,4-tetrahydroacridine as a hepatic microsomal metabolite of tacrine by high-performance liquid chromatography and electrochemistry

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The Prevalence of Dementia in Europe: A Collaborative Study of 1980–1990 Findings

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Clinical pharmacokinetics of intravenous and oral 9-amino-1,2,3,4-tetrahydroacridine, tacrine

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Measurements of tacrine and monoamines in brain by in vivo microdialysis argue against release of monoamines by tacrine at therapeutic doses

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An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro. Studies with human and rat liver microsomes

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Serum concentrations of tacrine hydrochloride predict its adverse effects in Alzheimer's disease

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Steady-state pharmacokinetics of tacrine in patients with Alzheimer's disease

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Suxamethonium "extension" by tetrahydroaminacrine

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Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species difference

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Velnacrine in Alzheimer's Disease : An Initial Appraisal of its Clinical Potential.

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Tacrine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in Alzheimer's disease

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12 December 2020

Tetrahydroaminoacridine and Alzheimer's disease

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12 December 2020

10.2165/00003088-199528060-00003

Identifiers

DOI

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Dimensions Publication ID

20 September 2017

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