(Q40480798)

20 September 2017

title

AP-1 and AP-3 facilitate lysosomal targeting of Batten disease protein CLN3 via its dileucine motif. (English)

1 reference

CLN3 lysosomal/endosomal transmembrane protein, battenin

20 September 2017

main subject

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GOA release 2020-03-11

author name string

Aija Kyttälä

1

1 reference

20 September 2017

Kristiina Yliannala

2

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20 September 2017

Peter Schu

3

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20 September 2017

Anu Jalanko

4

1 reference

20 September 2017

J Paul Luzio

5

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20 September 2017

language of work or name

English

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publication date

13 December 2004

1 reference

Journal of Biological Chemistry

20 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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20 September 2017

volume

280

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20 September 2017

issue

11

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20 September 2017

page(s)

10277-10283

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Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells

20 September 2017

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Action of BTN1, the yeast orthologue of the gene mutated in Batten disease

21 January 2018

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Elevated lysosomal pH in neuronal ceroid lipofuscinoses (NCLs)

21 January 2018

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A role in vacuolar arginine transport for yeast Btn1p and for human CLN3, the protein defective in Batten disease

21 January 2018

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The yeast model for Batten disease: a role for Btn2p in the trafficking of the Golgi-associated vesicular targeting protein, Yif1p

21 January 2018

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Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway

21 January 2018

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CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten disease

21 January 2018

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

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Lysosomal targeting of P-selectin is mediated by a novel sequence within its cytoplasmic tail

21 January 2018

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The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif

21 January 2018

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21 January 2018

Adaptor-related proteins

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Adaptable adaptors for coated vesicles

21 January 2018

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The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals

21 January 2018

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Molecular bases for the recognition of tyrosine-based sorting signals

21 January 2018

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Molecular architecture and functional model of the endocytic AP2 complex

21 January 2018

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A region from the medium chain adaptor subunit (mu) recognizes leucine- and tyrosine-based sorting signals

21 January 2018

1 reference

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Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

21 January 2018

1 reference

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Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

21 January 2018

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mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors

21 January 2018

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Differential use of two AP-3-mediated pathways by lysosomal membrane proteins

21 January 2018

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AP-3: an adaptor-like protein complex with ubiquitous expression

21 January 2018

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Characterization of the adaptor-related protein complex, AP-3

21 January 2018

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In polarized MDCK cells basolateral vesicles arise from clathrin-gamma-adaptin-coated domains on endosomal tubules

21 January 2018

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Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins

21 January 2018

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Assembly and function of AP-3 complexes in cells expressing mutant subunits.

21 January 2018

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The beta3A subunit gene (Ap3b1) of the AP-3 adaptor complex is altered in the mouse hypopigmentation mutant pearl, a model for Hermansky-Pudlak syndrome and night blindness

21 January 2018

1 reference

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Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

The Di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

Biosynthesis and intracellular targeting of the CLN3 protein defective in Batten disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

AP-1A and AP-3A lysosomal sorting functions

21 January 2018

1 reference

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Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor

21 January 2018

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Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes

21 January 2018

1 reference

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A di-leucine sequence and a cluster of acidic amino acids are required for dynamic retention in the endosomal recycling compartment of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

Retention and retrieval in the endoplasmic reticulum and the Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells

21 January 2018

1 reference

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AP-1 in Toxoplasma gondii mediates biogenesis of the rhoptry secretory organelle from a post-Golgi compartment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

The Batten disease gene product (CLN3p) is a Golgi integral membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

CLN3P, the Batten disease protein, localizes to membrane lipid rafts (detergent-resistant membranes).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

Defective intracellular transport of CLN3 is the molecular basis of Batten disease (JNCL)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

Batten disease: evaluation of CLN3 mutations on protein localization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

Isolation of a novel gene underlying batten disease, CLN3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411862200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411862200

1 reference

20 September 2017

1 reference