(Q40481673)

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A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Javier A Menendez

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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Luciano Vellon

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Inderjit Mehmi

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Poh K Teng

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

David W Griggs

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Ruth Lupu

6

1 reference

Europe PubMed Central

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6 January 2020

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1 January 2005

1 reference

Europe PubMed Central

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6 January 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

24

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6 January 2020

5

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Europe PubMed Central

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6 January 2020

761-779

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208238

0 references

Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

The CCN family of angiogenic regulators: the integrin connection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kappaB-dependent XIAP up-regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

MEK inhibition enhances paclitaxel-induced tumor apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of alphav integrins and vitronectin receptor identity in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Taxol binds to polymerized tubulin in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

CCN proteins: multifunctional signalling regulators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

A structural approach to the role of CCN (CYR61/CTGF/NOV) proteins in tumourigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

ERK1 associates with alpha(v)beta 3 integrin and regulates cell spreading on vitronectin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: regulation by 17beta-estradiol and overexpression in human breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Promotion of microtubule assembly in vitro by taxol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of ERK 1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyr61 promotes breast tumorigenesis and cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Paclitaxel. An update of its use in the treatment of metastatic breast cancer and ovarian and other gynaecological cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of Raf-1 and FAK in cell density-dependent regulation of integrin-dependent activation of MAP kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208238

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1208238

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15592521%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

ResearchGate publication ID

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