(Q40483262)

English

A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy (English)

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

author name string

Michael Lindenbaum

1

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Ed Perkins

2

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Erika Csonka

3

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Elena Fleming

4

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Lisa Garcia

5

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Amy Greene

6

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Lindsay Gung

7

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Gyula Hadlaczky

8

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Edmond Lee

9

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Josephine Leung

10

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Neil MacDonald

11

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Alexisann Maxwell

12

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Kathleen Mills

13

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Diane Monteith

14

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Carl F Perez

15

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Joan Shellard

16

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Sandy Stewart

17

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Tom Stodola

18

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Dana Vandenborre

19

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Sandy Vanderbyl

20

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Harry C Ledebur

21

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

7 December 2004

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Nucleic Acids Research

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

32

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

21

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

e172

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Human chromosome 21q22.2-qter carries a gene(s) responsible for downregulation of mlc2a and PEBP in Down syndrome model mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Use of natural and artificial chromosome vectors for animal transgenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Chromosome-based vectors for Mammalian cells: an overview.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Phage integrases: biology and applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Chromosome-based vectors for gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

A flow cytometry technique for measuring chromosome-mediated gene transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Satellite DNA-based artificial chromosomes for use in gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Efficient male and female germline transmission of a human chromosomal vector in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Mammalian artificial chromosome pilot production facility: large-scale isolation of functional satellite DNA-based artificial chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Analysis of a YAC with human telomeres and oriP from epstein-barr virus in yeast and 293 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Long-term stability of large insert genomic DNA episomal shuttle vectors in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Characterization of the chicken beta-globin insulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

A new bacteriophage P1-derived vector for the propagation of large human DNA fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

A YAC contig map of the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Dissociation of minor satellite from the centromere in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Sequence organization and cytological localization of the minor satellite of mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Insertional mutations in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Dynamic, structural, and regulatory aspects of lambda site-specific recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Bacteriophage P1 cloning system for the isolation, amplification, and recovery of DNA fragments as large as 100 kilobase pairs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

The cloning and production of recombinant human erythropoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Expression of a foreign gene in a line of transgenic mice is modulated by a chromosomal position effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

De novo chromosome formation in rodent cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Centromere formation in mouse cells cotransformed with human DNA and a dominant marker gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

Interaction of int protein with specific sites on λ att DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

22 September 2017

p27Kip1-mediated controlled proliferation technology increases constitutive sICAM production in CHO-DUKX adapted for growth in suspension and serum-free media

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

25 September 2017

Efficient in-vitro transfer of a 60-Mb mammalian artificial chromosome into murine and hamster cells using cationic lipids and dendrimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

25 September 2017

A new Chinese hamster ovary cell line expressing alpha2,6-sialyltransferase used as universal host for the production of human-like sialylated recombinant glycoproteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

25 September 2017

Site-specific recombination in human cells catalyzed by phage lambda integrase mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

25 September 2017

Stability of a functional murine satellite DNA-based artificial chromosome across mammalian species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

25 September 2017

The potential of extrachromosomal replicating vectors for gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

25 September 2017

Epstein-Barr-based episomal chromosomes shuttle 100 kb of self-replicating circular human DNA in mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

25 September 2017

Controlled transgene dosage and PAC-mediated transgenesis in mice using a chromosomal vector.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

17 June 2018

Efficient selection of transgenic mouse embryos using EGFP as a marker gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

17 June 2018

Relationship of mouse minor satellite DNA to centromere activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

17 June 2018

Formation of primary constriction and heterochromatin in mouse does not require minor satellite DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

17 June 2018

The oncogenic potential of Epstein-Barr virus nuclear antigen 1 in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

17 June 2018

Transfer and stable transgene expression of a mammalian artificial chromosome into bone marrow-derived human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

An unpaired mouse centromere passes consistently through male meiosis and does not significantly compromise spermatogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

Retrofitting of a satellite repeat DNA-based murine artificial chromosome (ACes) to contain loxP recombination sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

Genetic manipulation of mouse embryonic stem cells by mutant lambda integrase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

Insertion of a loxP site in a size-reduced human accessory chromosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

Expression of a reporter gene after microinjection of mammalian artificial chromosomes into pronuclei of bovine zygotes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

Novel generation of human satellite DNA-based artificial chromosomes in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535698

20 August 2018

Site-specific recombination in eukaryotic cells mediated by mutant lambda integrases: implications for synaptic complex formation and the reactivity of episomal DNA segments

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronuclear microinjection of purified artificial chromosomes for generation of transgenic mice: pick-and-inject technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction of artificial chromosomes in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and properties of Int-h, a variant protein involved in site-specific recombination of bacteriophage lambda

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extent of sequence homology required for bacteriophage lambda site-specific recombination

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

De novo chromosome formations by large-scale amplification of the centromeric region of mouse chromosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a megareplicon covering megabases of centromeric chromosome segments

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saphenous vein puncture for blood sampling of the mouse, rat, hamster, gerbil, guinea pig, ferret and mink

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the directionality of lambda site-specific recombination catalyzed by mutant integrases in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15585659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GNH169

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40483262&oldid=1898074052"