(Q40483692)

English

Anti-angiogenic effects of SN38 (active metabolite of irinotecan): inhibition of hypoxia-inducible factor 1 alpha (HIF-1alpha)/vascular endothelial growth factor (VEGF) expression of glioma and growth of endothelial cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Anti-angiogenic effects of SN38 (active metabolite of irinotecan): inhibition of hypoxia-inducible factor 1 alpha (HIF-1alpha)/vascular endothelial growth factor (VEGF) expression of glioma and growth of endothelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

0 references

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angiogenesis inhibitor

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Hiroshi Kamiyama

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Shingo Takano

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Koji Tsuboi

3

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Akira Matsumura

4

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

publication date

4 December 2004

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Journal of Cancer Research and Clinical Oncology

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

131

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

205-213

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

https://scigraph.springernature.com/pub.10.1007/s00432-004-0642-z

0 references

Irinotecan: promising activity in the treatment of malignant glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prospective blinded study of the predictive value of an extreme drug resistance assay in patients receiving CPT-11 for recurrent glioma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis and proteins of the hemostatic system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factors reverse the impaired sprouting of microvessels from aged mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic chemotherapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is HIF-1 alpha a valid therapeutic target?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIF hydroxylation and the mammalian oxygen-sensing pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic effects of the novel camptothecin ST1481 (gimatecan) in human tumor xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Camptothecins: a review of their development and schedules of administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro pharmacological characterizations of the anti-angiogenic and anti-tumor cell migration properties mediated by microtubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor activating matrix metalloproteinase in ascitic fluid during peritoneal dissemination of ovarian cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic potential of 10-hydroxycamptothecin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-vascular endothelial growth factor antibody and nimustine as combined therapy: effects on tumour growth and angiogenesis in human glioblastoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting HIF-1 for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-angiogenesis and angioprevention: mechanisms, problems and perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic effects of camptothecin analogues 9-amino-20(S)-camptothecin, topotecan, and CPT-11 studied in the mouse cornea model

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan in the treatment of glioma patients: current and future studies of the North Central Cancer Treatment Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic potential of camptothecin and topotecan

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in cancer and other diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triplet repeat-containing ribosomal protein L14 gene in immortalized human endothelial cell line (t-HUE4)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topotecan is anti-angiogenic in experimental hepatoblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel use of an established agent: Topotecan is anti-angiogenic in experimental Wilms tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rationale and future potential of angiogenesis inhibitors in neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current chemotherapy for glioblastoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-arterial cisplatin plus oral etoposide for the treatment of recurrent malignant glioma: a phase II study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of human endothelial cell lines in a serum-free culture and its application for expression of transfected prepro endothelin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical translation of angiogenesis inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topotecan inhibits VEGF- and bFGF-induced vascular endothelial cell migration via downregulation of the PI3K-Akt signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of angiogenesis by hypoxia: role of the HIF system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenic growth factors in neural embryogenesis and neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concentration of vascular endothelial growth factor in the serum and tumor tissue of brain tumor patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15583935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-004-0642-Z

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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