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The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others.
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
review article
1 reference
stated in
Europe PubMed Central
title
The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
main subject
mast cells
0 references
author
Stephen J. Galli
series ordinal
1
stated as
S J Galli
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
author name string
M Tsai
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
B K Wershil
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
language of work or name
English
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publication date
1 April 1993
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
published in
The American Journal of Pathology
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
volume
142
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
page(s)
965-974
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
issue
4
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
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Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosa
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The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus.
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Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.
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New insights into "the riddle of the mast cells": microenvironmental regulation of mast cell development and phenotypic heterogeneity.
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Steel locus defines new multipotent growth factor.
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22 September 2017
Primary structure and functional expression of rat and human stem cell factor DNAs
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22 September 2017
Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent. Partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha.
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PubMed Central
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22 September 2017
Characterization of Ws mutant allele of rats: a 12-base deletion in tyrosine kinase domain of c-kit gene.
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PubMed Central
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22 September 2017
Deletion of the c-kit protooncogene in the human developmental defect piebald trait.
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Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism
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22 September 2017
Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor.
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22 September 2017
The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype
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PubMed Central
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22 September 2017
The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.
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PubMed Central
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22 September 2017
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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22 September 2017
Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors.
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PubMed Central
reference URL
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Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms.
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22 September 2017
The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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22 September 2017
Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor.
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stated in
PubMed Central
reference URL
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22 September 2017
Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.
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22 September 2017
The human recombinant c-kit receptor ligand, rhSCF, induces mediator release from human cutaneous mast cells and enhances IgE-dependent mediator release from both skin mast cells and peripheral blood basophils.
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PubMed Central
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22 September 2017
The Steel factor.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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22 September 2017
Differential expression of secretory granule proteases in mouse mast cells exposed to interleukin 3 and c-kit ligand
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
22 September 2017
c-Kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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22 September 2017
c-kit ligand: a unique potentiator of mediator release by human lung mast cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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22 September 2017
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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22 September 2017
Hereditary anemias of the mouse: a review for geneticists.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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22 September 2017
Decreased production of mast cells in S1/S1d anemic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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25 September 2017
Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
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25 September 2017
Mast cell-dependent amplification of an immunologically nonspecific inflammatory response. Mast cells are required for the full expression of cutaneous acute inflammation induced by phorbol 12-myristate 13-acetate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
25 September 2017
125I-fibrin deposition in IgE-dependent immediate hypersensitivity reactions in mouse skin. Demonstration of the role of mast cells using genetically mast cell-deficient mice locally reconstituted with cultured mast cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Proliferation and differentiation in culture of mast cell progenitors derived from mast cell-deficient mice of genotype W/Wv.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
The mast cell-committed progenitor. II. W/Wv mice do not make mast cell-committed progenitors and S1/S1d fibroblasts do not support development of normal mast cell-committed progenitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver--conditioned medium.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Requirement for mast cell growth factor for primordial germ cell survival in culture.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
The kit ligand: a cell surface molecule altered in steel mutant fibroblasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Identification of a ligand for the c-kit proto-oncogene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Stimulation of mouse connective tissue-type mast cells by hemopoietic stem cell factor, a ligand for the c-kit receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
The rat c-kit ligand, stem cell factor, induces c-kit receptor-dependent mouse mast cell activation in vivo. Evidence that signaling through the c-kit receptor can induce expression of cellular function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
Effect of IL-3 and stem cell factor on the appearance of human basophils and mast cells from CD34+ pluripotent progenitor cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
15 June 2018
W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
17 June 2018
The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
20 August 2018
Phorbol 12-myristate 13-acetate-induced development of functionally active mast cells in W/Wv but not Sl/Sld genetically mast cell-deficient mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1886888
retrieved
20 August 2018
Identifiers
PMCID
1886888
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
PubMed ID
7682764
1 reference
stated in
Europe PubMed Central
PMCID
1886888
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7682764%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 October 2019
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