(Q40487777)

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Use and specificity of breast cancer antigen/milk protein BA46 for generating anti-self-cytotoxic T lymphocytes by recombinant adeno-associated virus-based gene loading of dendritic cells

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Europe PubMed Central

21 September 2017

Use and specificity of breast cancer antigen/milk protein BA46 for generating anti-self-cytotoxic T lymphocytes by recombinant adeno-associated virus-based gene loading of dendritic cells (English)

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Europe PubMed Central

21 September 2017

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Everardo Cobos

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21 September 2017

author name string

Yong Liu

1

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Maurizio Chiriva-Internati

2

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21 September 2017

Changxuan You

3

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Europe PubMed Central

21 September 2017

Rongcheng Luo

4

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Europe PubMed Central

21 September 2017

Hong You

5

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21 September 2017

C Krishna Prasad

6

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21 September 2017

Fabio Grizzi

7

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21 September 2017

V Suzanne Klimberg

9

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21 September 2017

Helen Kay

10

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21 September 2017

Jawahar L Mehta

11

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21 September 2017

Paul L Hermonat

12

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21 September 2017

publication date

1 March 2005

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21 September 2017

Cancer Gene Therapy

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21 September 2017

12

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3

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304-312

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21 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700785

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Update on HER-2 as a target for cancer therapy: HER2/neu peptides as tumour vaccines for T cell recognition

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Peptide HER2(776-788) represents a naturally processed broad MHC class II-restricted T cell epitope

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The generation of both T killer and Th cell clones specific for the tumor-associated antigen HER2 using retrovirally transduced dendritic cells

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Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain

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Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion

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The dendritic cell system and its role in immunogenicity

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

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Proliferating dendritic cell progenitors in human blood

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Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity

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Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines

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Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo

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Generation of tumor-specific cytolytic T lymphocytes from peripheral blood of cervical cancer patients by in vitro stimulation with a synthetic human papillomavirus type 16 E7 epitope

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Dendritic cells infected with poxviruses encoding MART-1/Melan A sensitize T lymphocytes in vitro

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Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells

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Gene transfer into hematopoietic progenitor cells mediated by an adeno-associated virus vector

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Efficient generation of cytotoxic T lymphocytes against cervical cancer cells by adeno-associated virus/human papillomavirus type 16 E7 antigen gene transduction into dendritic cells

1 reference

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Rapid induction of cytotoxic T-cell response against cervical cancer cells by human papillomavirus type 16 E6 antigen gene delivery into human dendritic cells by an adeno-associated virus vector

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A positive correlation between the precursor frequency of cytotoxic lymphocytes to autologous Epstein-Barr virus-transformed B cells and antibody titer level against Epstein-Barr virus-associated nuclear antigen in healthy seropositive individuals

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A helper virus-free packaging system for recombinant adeno-associated virus vectors

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21 January 2018

Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column.

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Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8(+) cytotoxic T lymphocytes

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Characterization of novel breast carcinoma-associated BA46-derived peptides in HLA-A2.1/D(b)-beta2m transgenic mice

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21 January 2018

Expression of human milk fat globulin proteins in cells of haemopoietic origin

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Adeno-associated virus vectors preferentially transduce cells in S phase.

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DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors

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Testing recombinant adeno-associated virus-gene loading of dendritic cells for generating potent cytotoxic T lymphocytes against a prototype self-antigen, multiple myeloma HM1.24.

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Induction of protective anti-tumor immunity by gene-modified dendritic cells.

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In vivo and in vitro modulation of immune stimulatory capacity of primary dendritic cells by adenovirus-mediated gene transduction

1 reference

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Single cell analysis of cytokine expression kinetics by human CD4+ T-cell clones during activation or tolerance induction

1 reference

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7 January 2021

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Characterization of accessory molecules in murine lung dendritic cell function: roles for CD80, CD86, CD54, and CD40L

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7 January 2021

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10.1038/SJ.CGT.7700785

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Europe PubMed Central

21 September 2017

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21 September 2017

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