(Q40488292)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Novel CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells (English)

1 reference

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5 January 2020

3

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5 January 2020

author name string

Karen Swales

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Satoru Kakizaki

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Kaoru Inoue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Kaoru Kobayashi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Masahiko Negishi

6

1 reference

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5 January 2020

language of work or name

English

0 references

publication date

24 November 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 January 2020

published in

1 reference

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5 January 2020

volume

280

1 reference

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5 January 2020

issue

5

1 reference

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5 January 2020

page(s)

3458-3466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

5 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Phenobarbital response elements of cytochrome P450 genes and nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Regulatory DNA elements of phenobarbital-responsive cytochrome P450 CYP2B genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Gene induction by Phenobarbital: an update on an old question that receives key novel answers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Retinoic acid receptors and muscle b-HLH proteins: partners in retinoid-induced myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Cytoplasmic Accumulation of the Nuclear Receptor CAR by a Tetratricopeptide Repeat Protein in HepG2 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Characterization of phenobarbital-inducible mouse Cyp2b10 gene transcription in primary hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

In vivo phenobarbital treatment increases protein binding to a putative AP-1 site in the CYP2B2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

A model for the transcriptional regulation of the CYP2B1/B2 gene in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Involvement of synthesis and phosphorylation of nuclear protein factors that bind to the positive cis-acting element in the transcriptional activation of the CYP2B1/B2 gene by phenobarbitone in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Phenobarbitone-mediated translocation of the cytosolic proteins interacting with the 5'-proximal region of rat liver CYP2B1/B2 gene into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Context-dependent transcription: all politics is local

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The mechanism of transcriptional synergy of an in vitro assembled interferon-beta enhanceosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

DNA-binding activity of the transcription factor upstream stimulatory factor 1 (USF-1) is regulated by cyclin-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

PKA, PKC, and the Protein Phosphatase 2A Influence HAND Factor Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The ornithine decarboxylase gene is a transcriptional target of c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Cyclic amplification and selection of targets for multicomponent complexes: myogenin interacts with factors recognizing binding sites for basic helix-loop-helix, nuclear factor 1, myocyte-specific enhancer-binding factor 2, and COMP1 factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Altered cleavage of DNA sequences by bleomycin and its deglycosylated derivative in the presence of actinomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

A new method for sequencing DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411318200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411318200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15563456%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference