(Q40490888)

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Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cells

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cells (English)

1 reference

Europe PubMed Central

21 September 2017

1

1 reference

Europe PubMed Central

21 September 2017

author name string

Douwe Samplonius

2

1 reference

Europe PubMed Central

21 September 2017

Bart-Jan Kroesen

3

1 reference

Europe PubMed Central

21 September 2017

Linda van Genne

4

1 reference

Europe PubMed Central

21 September 2017

Lou de Leij

5

1 reference

Europe PubMed Central

21 September 2017

Wijnand Helfrich

6

1 reference

Europe PubMed Central

21 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 September 2004

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

6

1 reference

Europe PubMed Central

21 September 2017

5

1 reference

Europe PubMed Central

21 September 2017

636-645

1 reference

Europe PubMed Central

21 September 2017

Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

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Quantification and characterization of the bystander effect in prostate cancer cells following adenovirus-mediated FasL expression

1 reference

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22 September 2017

Treatment of relapsed CD20+ Hodgkin lymphoma with the monoclonal antibody rituximab is effective and well tolerated: results of a phase 2 trial of the German Hodgkin Lymphoma Study Group

1 reference

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Incidence and nature of CD20-negative relapses following rituximab therapy in aggressive B-cell non-Hodgkin's lymphoma: a retrospective review.

1 reference

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22 September 2017

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

22 September 2017

Caspase-10 is an initiator caspase in death receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

22 September 2017

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

22 September 2017

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

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Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

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22 September 2017

Bystander killing of tumour cells by antibody-targeted enzymatic activation of a glucuronide prodrug

1 reference

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22 September 2017

Therapy of B-cell lymphoma with anti-CD20 antibodies can result in the loss of CD20 antigen expression

1 reference

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A recombinant, fully human monoclonal antibody with antitumor activity constructed from phage-displayed antibody fragments

1 reference

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22 September 2017

Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro

1 reference

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22 September 2017

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

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22 September 2017

Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins

1 reference

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22 September 2017

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

1 reference

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Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization.

1 reference

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Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

1 reference

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22 September 2017

Detection of a putative 30-kDa ligand of the cluster-2 antigen.

1 reference

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22 September 2017

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

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Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient. Implications for the study of tumor antigens

1 reference

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Phenotypic heterogeneity of melanoma. Relation to the differentiation program of melanoma cells

1 reference

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22 September 2017

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

25 September 2017

Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

25 September 2017

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

17 June 2018

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1 reference

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17 June 2018

Epitope mapping of SCLC-cluster-2 MAbs and generation of antibodies directed against new EGP-2 epitopes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

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High level expression of tissue inhibitor of metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification

1 reference

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Biological and molecular analysis of a low-grade recurrence of a glioblastoma multiforme.

1 reference

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3 July 2018

Target cell-restricted and -enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma-associated antigen EGP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1531668

20 August 2018

Gap junction-mediated bystander effect in primary cultures of human malignant gliomas with recombinant expression of the HSVtk gene

1 reference

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Safety and activity of docetaxel and trastuzumab in HER2 overexpressing metastatic breast cancer: a pilot phase II study

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Radioiodinated (I-125) monoclonal antibody 425 in the treatment of high grade glioma patients: ten-year synopsis of a novel treatment.

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1 reference

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Three new prodrugs for suicide gene therapy using carboxypeptidase G2 elicit bystander efficacy in two xenograft models

1 reference

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20 August 2018

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

1 reference

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20 August 2018

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

1 reference

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1 reference

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20 August 2018

The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TRAIL DISCussion: It is FADD and caspase-8!

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The epithelial glycoprotein 2 (EGP-2) promoter-driven epithelial-specific expression of EGP-2 in transgenic mice: a new model to study carcinoma-directed immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intratumoral genetic heterogeneity in Barrett adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-TRAIL can overcome TRAIL resistance and induce a bystander effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1593/NEO.04229

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

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