(Q40493583)

English

Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

21 September 2017

Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease (English)

1 reference

Europe PubMed Central

21 September 2017

sickle-cell disease

0 references

5

object named as

Carlos F Barbas

1 reference

Europe PubMed Central

21 September 2017

author name string

Torbjörn Gräslund

1

1 reference

Europe PubMed Central

21 September 2017

Xuelin Li

2

1 reference

Europe PubMed Central

21 September 2017

Laurent Magnenat

3

1 reference

Europe PubMed Central

21 September 2017

Mikhail Popkov

4

1 reference

Europe PubMed Central

21 September 2017

language of work or name

0 references

publication date

10 November 2004

1 reference

Europe PubMed Central

21 September 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

21 September 2017

280

1 reference

Europe PubMed Central

21 September 2017

5

1 reference

Europe PubMed Central

21 September 2017

3707-3714

1 reference

Europe PubMed Central

21 September 2017

Regulated expression of human A gamma-, beta-, and hybrid gamma beta-globin genes in transgenic mice: manipulation of the developmental expression patterns.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

An embryonic pattern of expression of a human fetal globin gene in transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Human globin gene promoter sequences are sufficient for specific expression of a hybrid gene transfected into tissue culture cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Hemoglobin switching: new insights

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Transcription complex stability and chromatin dynamics in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Locus control regions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Fetal gene reactivation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Genetic correction of sickle cell disease: insights using transgenic mouse models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Toward rules relating zinc finger protein sequences and DNA binding site preferences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Building zinc fingers by selection: toward a therapeutic application

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Positive and negative regulation of endogenous genes by designed transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Selective inhibition of P-glycoprotein expression in multidrug-resistant tumor cells by a designed transcriptional regulator.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Engineering polydactyl zinc-finger transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Transcriptional coregulators in development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

c-Myc target gene specificity is determined by a post-DNAbinding mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Krüppel-associated boxes are potent transcriptional repression domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

FKLF, a novel Krüppel-like factor that activates human embryonic and fetal beta-like globin genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

A point mutation in the A gamma-globin gene promoter in Greek hereditary persistence of fetal haemoglobin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

G to A substitution in the distal CCAAT box of the A gamma-globin gene in Greek hereditary persistence of fetal haemoglobin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

In vivo protein-DNA interactions at the beta-globin gene locus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Identification and characterization of mechanistically distinct inducers of gamma-globin transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

The influence of fetal hemoglobin on the clinical expression of sickle cell anemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

A versatile framework for the design of ligand-dependent, transgene-specific transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Induction of angiogenesis in a mouse model using engineered transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Specific expression of a foreign β-globin gene in erythroid cells of transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406809200

21 January 2018

Identifiers

10.1074/JBC.M406809200

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40493583&oldid=1901759097"