(Q40498088)

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The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential

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scholarly article

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Europe PubMed Central

21 September 2017

The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential (English)

1 reference

Europe PubMed Central

21 September 2017

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based on heuristic

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3

object named as

Kenneth Maiese

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Europe PubMed Central

21 September 2017

author name string

Zhao Zhong Chong

1

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Europe PubMed Central

21 September 2017

Shi-Hua Lin

2

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Europe PubMed Central

21 September 2017

publication date

1 July 2004

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Europe PubMed Central

21 September 2017

Journal of Cerebral Blood Flow & Metabolism

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Europe PubMed Central

21 September 2017

24

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Europe PubMed Central

21 September 2017

728-743

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21 September 2017

7

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Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1097/01.wcb.0000122746.72175.0e

0 references

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

1 reference

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21 January 2018

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

1 reference

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Human papillomavirus (HPV) 16 E6 sensitizes cells to atractyloside-induced apoptosis: role of p53, ICE-like proteases and the mitochondrial permeability transition

1 reference

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21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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21 January 2018

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

1 reference

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21 January 2018

Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases

1 reference

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Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways

1 reference

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21 January 2018

Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury

1 reference

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21 January 2018

The NAD+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate.

1 reference

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21 January 2018

Protective effects of benidipine on hydrogen peroxide-induced injury in rat isolated hearts

1 reference

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Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

1 reference

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2-Deoxy-D-glucose prevents and nicotinamide potentiates 3, 4-methylenedioxymethamphetamine-induced serotonin neurotoxicity.

1 reference

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21 January 2018

Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells

1 reference

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21 January 2018

Kinetics of apoptotic markers in exogeneously induced apoptosis of EL4 cells.

1 reference

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Akt1 protects against inflammatory microglial activation through maintenance of membrane asymmetry and modulation of cysteine protease activity

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Critical role for Akt1 in the modulation of apoptotic phosphatidylserine exposure and microglial activation

1 reference

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Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

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Nicotinamide prevents N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats and C57BL mice

1 reference

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21 January 2018

Cytochrome c-induced cytosolic nicotinamide adenine dinucleotide oxidation, mitochondrial permeability transition, and apoptosis

1 reference

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21 January 2018

AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR.

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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Prevention of nitric oxide-induced neuronal injury through the modulation of independent pathways of programmed cell death.

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Nicotinamide: necessary nutrient emerges as a novel cytoprotectant for the brain

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21 January 2018

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

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Neuroprotection in Parkinson disease

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Fas antigen modulates ultraviolet B-induced apoptosis of SVHK cells: sequential activation of caspases 8, 3, and 1 in the apoptotic process

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Redox control of cell death

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Nitric oxide induction of neuronal endonuclease activity in programmed cell death.

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Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

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Phagocytic clearance of apoptotic neurons by Microglia/Brain macrophages in vitro: involvement of lectin-, integrin-, and phosphatidylserine-mediated recognition.

1 reference

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21 January 2018

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

1 reference

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21 January 2018

Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

1 reference

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21 January 2018

Identifiers

10.1097/01.WCB.0000122746.72175.0E

1 reference

Europe PubMed Central

21 September 2017

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0 references

1 reference

Europe PubMed Central

21 September 2017

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