(Q40504118)

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Chimeric G alpha i2/G alpha 13 proteins reveal the structural requirements for the binding and activation of the RGS-like (RGL)-containing Rho guanine nucleotide exchange factors (GEFs) by G alpha 13.

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4 January 2020

Chimeric G alpha i2/G alpha 13 proteins reveal the structural requirements for the binding and activation of the RGS-like (RGL)-containing Rho guanine nucleotide exchange factors (GEFs) by G alpha 13 (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485891%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Jose Vazquez-prado

1

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4 January 2020

Maria Domenica Castellone

3

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4 January 2020

J. Silvio Gutkind

5

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4 January 2020

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Hiroshi Miyazaki

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4 January 2020

Hidemi Teramoto

4

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14 October 2004

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4 January 2020

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8

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Journal of Biological Chemistry

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4 January 2020

279

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4 January 2020

52

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4 January 2020

54283-54290

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4 January 2020

Rho GTPases in cell biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

1 reference

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Rho and Rac take center stage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes

1 reference

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The role of Rho in G protein-coupled receptor signal transduction

1 reference

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21 January 2018

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

1 reference

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21 January 2018

The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

1 reference

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21 January 2018

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

1 reference

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21 January 2018

Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.

1 reference

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21 January 2018

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Potent activation of RhoA by Galpha q and Gq-coupled receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Direct interaction of p21-activated kinase 4 with PDZ-RhoGEF, a G protein-linked Rho guanine exchange factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

The many faces of G protein signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Structure of the rgRGS domain of p115RhoGEF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Galpha 13 requires palmitoylation for plasma membrane localization, Rho-dependent signaling, and promotion of p115-RhoGEF membrane binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Lipid modifications of G proteins: alpha subunits are palmitoylated

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Galpha12 requires acylation for its transforming activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Functional roles for fatty acylated amino-terminal domains in subcellular localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Regulators of G-protein signalling as new central nervous system drug targets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Structure of the RGS-like Domain from PDZ-RhoGEF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410594200

21 January 2018

Identifiers

10.1074/JBC.M410594200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485891%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15485891%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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