(Q40506957)

21 September 2017

Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215. (English)

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21 September 2017

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Qiyuan Liu

1

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21 September 2017

Satoshi Kaneko

2

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21 September 2017

Lin Yang

3

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21 September 2017

Richard I Feldman

4

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21 September 2017

Santo V Nicosia

5

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21 September 2017

Jiandong Chen

6

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21 September 2017

Jin Q Cheng

7

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21 September 2017

language of work or name

English

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publication date

6 October 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

52175-52182

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21 September 2017

50

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Aurora kinases link chromosome segregation and cell division to cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Positive feedback regulation between Akt2 and MyoD during muscle differentiation. Cloning of Akt2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

A role for endothelial NO synthase in LTP revealed by adenovirus-mediated inhibition and rescue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

pEg2 aurora-A kinase, histone H3 phosphorylation, and chromosome assembly in Xenopus egg extract

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Involvement of Aurora A kinase during meiosis I-II transition in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Human TPX2 is required for targeting Aurora-A kinase to the spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Small peptides activate the latent sequence-specific DNA binding function of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Phosphorylation studies on rat p53 using the baculovirus expression system. Manipulation of the phosphorylation state with okadaic acid and influence on DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406802200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406802200

1 reference

21 September 2017

1 reference