(Q40517235)

21 September 2017

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title

The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents (English)

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21 September 2017

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J M Hyatt

1

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21 September 2017

P S McKinnon

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2

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21 September 2017

G S Zimmer

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3

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21 September 2017

J J Schentag

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4

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21 September 2017

language of work or name

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1 February 1995

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Clinical Pharmacokinetics

21 September 2017

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21 September 2017

28

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21 September 2017

2

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21 September 2017

143-160

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https://scigraph.springernature.com/pub.10.2165/00003088-199528020-00005

21 September 2017

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12 December 2020

Potential impact of quantitative susceptibility tests on the design of aminoglycoside dosing regimens

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Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia

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The association of aminoglycoside plasma levels with mortality in patients with gram-negative bacteremia.

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Routine monitoring of serum vancomycin concentrations: waiting for proof of its value

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Activities of pefloxacin and ciprofloxacin in experimentally induced Pseudomonas pneumonia in neutropenic guinea pigs

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12 December 2020

Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis

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12 December 2020

Antibiotic therapy of infections due to Pseudomonas aeruginosa in normal and granulocytopenic mice: comparison of murine and human pharmacokinetics

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12 December 2020

Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients

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12 December 2020

Impact of dosing intervals on activity of gentamicin and ticarcillin against Pseudomonas aeruginosa in granulocytopenic mice

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Kinetics of antimicrobial activity

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Role for Dual Individualization with Cefmenoxime

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Vancomycin in severe staphylococcal infections

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Bactericidal Activity of Cephalosporins in an In Vitro Model Simulating Serum Levels

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A randomized study of carbenicillin plus cefamandole or tobramycin in the treatment of febrile episodes in cancer patients

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Killing and regrowth of bacteria in vitro: a review.

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Evaluation of teicoplanin for treatment of endocarditis caused by gram-positive cocci in 20 patients

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In vitro evaluation of the determinants of bactericidal activity of ampicillin dosing regimens against Escherichia coli

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Evaluation of pefloxacin in experimental Escherichia coli meningitis

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Effect of dose and schedule on cefoperazone pharmacodynamics in an in Vitro model of infection in a neutropenic host

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Effects of dosage, peak and trough concentrations in serum, protein binding, and bactericidal rate on efficacy of teicoplanin in a rabbit model of endocarditis

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Pharmacodynamics and pharmacokinetics of antibiotics with special reference to the fluoroquinolones

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Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis

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Pharmacodynamics of amikacin in vitro and in mouse thigh and lung infections

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Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model

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Antistaphylococcal activities of teicoplanin and vancomycin in vitro and in an experimental infection

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New In Vitro Model to Study the Effect of Antibiotic Concentration and Rate of Elimination on Antibacterial Activity

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Human pharmacodynamics of beta-lactams, aminoglycosides and their combination

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12 December 2020

Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models.

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Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration

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Resistance occurring after fluoroquinolone therapy of experimental Pseudomonas aeruginosa peritonitis

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Use of serum ultrafiltrate in the serum dilution test

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Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection models

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Optimal times above MICs of ceftibuten and cefaclor in experimental intra-abdominal infections

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Clinical pharmacology and efficacy of vancomycin in pediatric patients.

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Pharmacokinetic contributions to postantibiotic effects. Focus on aminoglycosides

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Comparative efficacy of amoxicillin-clavulanate, cloxacillin, and vancomycin against methicillin-sensitive and methicillin-resistant Staphylococcus aureus endocarditis in rats

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12 December 2020

Tests for bactericidal effects of antimicrobial agents: technical performance and clinical relevance

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12 December 2020

In vitro postantibiotic effects following multiple exposures of cefotaxime, ciprofloxacin, and gentamicin against Escherichia coli in pooled human cerebrospinal fluid and Mueller-Hinton broth

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12 December 2020

Combination therapy with ciprofloxacin plus azlocillin against Pseudomonas aeruginosa: effect of simultaneous versus staggered administration in an in vitro model of infection

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12 December 2020

Comparative efficacy of daptomycin, vancomycin, and cloxacillin for the treatment of Staphylococcus aureus endocarditis in rats and role of test conditions in this determination

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12 December 2020

Effect of schedule of administration on the therapeutic efficacy of penicillin; importance of the aggregate time penicillin remains at effectively bactericidal levels

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12 December 2020

What is the evidence for once-daily aminoglycoside therapy?

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12 December 2020

Vancomycin therapeutic drug monitoring: is it necessary?

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12 December 2020

Correlation of pharmacokinetic indices with therapeutic outcome in patients receiving aminoglycosides

1 reference

12 December 2020

Early stages of in vitro killing curve of LY146032 and vancomycin for Staphylococcus aureus

1 reference

12 December 2020

10.2165/00003088-199528020-00005

Identifiers

DOI

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Dimensions Publication ID

21 September 2017

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