(Q40517852)

English

Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2.

scientific article published on 8 September 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2. (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Michael Lee

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Ji-Young Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Wayne B Anderson

3

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

language of work or name

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publication date

8 September 2004

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

47

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

48692-48701

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

The complexity of Raf-1 regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Isotype-specific functions of Raf kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Interactions between Ras and Raf: key regulatory proteins in cellular transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Mechanisms regulating Raf-1 activity in signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Untying the regulation of the Raf-1 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Multiple pathways control protein kinase C phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Protein kinase C-epsilon associates with the Raf-1 kinase and induces the production of growth factors that stimulate Raf-1 activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Protein kinase Cepsilon is oncogenic in colon epithelial cells by interaction with the ras signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Reversion of Ras- and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of protein kinase C lambda is accompanied by the loss of constitutive nuclear mitogen-activated protein k

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Redox signaling: hydrogen peroxide as intracellular messenger

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Redox-dependent signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Oxidative stress and gene regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Oxidant signals and oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Oxygen radicals and signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Sequential modification of serines 621 and 624 in the Raf-1 carboxyl terminus produces alterations in its electrophoretic mobility.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Selected glimpses into the activation and function of Src kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

The synergistic activation of Raf-1 kinase by phorbol myristate acetate and hydrogen peroxide in NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

The 33-kDa C-terminal domain of Raf-1 protein kinase exhibits a Ras-independent serum- and phorbol ester-induced shift in gel mobility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Kinase suppressor of Ras is ceramide-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Protein kinase C alpha activates RAF-1 by direct phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Ras signaling: PP2A puts Ksr and Raf in the right place

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

The requirement of specific membrane domains for Raf-1 phosphorylation and activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

MEK kinase activity is not necessary for Raf-1 function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Split personalities: the agonistic antagonist Sprouty

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Spred is a Sprouty-related suppressor of Ras signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Protein kinase C signaling and oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Activation of Raf by ionizing radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403132200

21 January 2018

Identifiers

10.1074/JBC.M403132200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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