(Q44226145)

1 December 2017

The requirement of specific membrane domains for Raf-1 phosphorylation and activation (English)

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1 December 2017

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Kendall D Carey

1

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1 December 2017

Robert T Watson

series ordinal

2

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1 December 2017

Jeffrey E Pessin

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3

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1 December 2017

Philip J S Stork

series ordinal

4

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1 December 2017

language of work or name

English

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publication date

21 November 2002

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Journal of Biological Chemistry

1 December 2017

12

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based on heuristic

inferred from page(s)

published in

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1 December 2017

278

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1 December 2017

3185-3196

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1 December 2017

5

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Ras and relatives--job sharing and networking keep an old family together

1 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

New insights into the interaction of Ras with the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

The caveolae membrane system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Regulating c-Ras function. cholesterol depletion affects caveolin association, GTP loading, and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Agonist-dependent traffic of raft-associated Ras and Raf-1 is required for activation of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Differential activation of the Rac pathway by Ha-Ras and K-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Activation of Raf as a result of recruitment to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Physical association with ras enhances activation of membrane-bound raf (RafCAAX).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Positive and negative regulation of Raf kinase activity and function by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

A detergent-free method for purifying caveolae membrane from tissue culture cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

The complexity of Raf-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Functions of lipid rafts in biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Activated K-Ras and H-Ras display different interactions with saturable nonraft sites at the surface of live cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Ras-effector interactions, the problem of specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Conspiracy theory: RAS and RAF do not act alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Ras signalling on the endoplasmic reticulum and the Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Which Ras rides the raft?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Localization of platelet-derived growth factor-stimulated phosphorylation cascade to caveolae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Function of the Rho family GTPases in Ras-stimulated Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Differential effects of cAMP in neurons and astrocytes. Role of B-raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207014200

21 January 2018

Identifiers

DOI

10.1074/JBC.M207014200

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1 December 2017

1 reference