(Q40525596)

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Basic fibroblast growth factor-induced cell death is effected through sustained activation of p38MAPK and up-regulation of the death receptor p75NTR.

scientific article published on 13 August 2004

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Europe PubMed Central

PubMed publication ID

21 September 2017

Basic fibroblast growth factor-induced cell death is effected through sustained activation of p38MAPK and up-regulation of the death receptor p75NTR. (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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James R Boyne

3

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author name string

Andrew J K Williamson

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Benjamin C Dibling

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Peter Selby

4

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Susan A Burchill

5

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Europe PubMed Central

PubMed publication ID

21 September 2017

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publication date

13 August 2004

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Europe PubMed Central

PubMed publication ID

21 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 September 2017

279

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Europe PubMed Central

PubMed publication ID

21 September 2017

46

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

47912-47928

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Ewing sarcoma family of tumors

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The Ewing family of tumors and the search for the Achilles' heel.

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EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells

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Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor

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The metastatic ability of Ewing's sarcoma cells is modulated by stem cell factor and by its receptor c-kit

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Basic fibroblast growth factor as a growth inhibitor for cultured human tumor cells

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Basic fibroblast growth factor (bFGF)-induced cell death is mediated through a caspase-dependent and p53-independent cell death receptor pathway

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A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

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Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

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Mitogen-activated protein kinase pathways

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Rsk1 mediates a MEK-MAP kinase cell survival signal

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Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway

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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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Senescence of human fibroblasts induced by oncogenic Raf.

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p38 mitogen-activated protein kinase activation is required for fibroblast growth factor-2-stimulated cell proliferation but not differentiation

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21 January 2018

Protein kinase cascades activated by stress and inflammatory cytokines

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

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21 January 2018

p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient

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21 January 2018

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

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21 January 2018

Convergence of MAP kinase pathways on the ternary complex factor Sap-1a

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21 January 2018

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

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21 January 2018

p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389.

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21 January 2018

The stress-activated protein kinase subfamily of c-Jun kinases

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c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

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21 January 2018

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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21 January 2018

Phosphorylation of c-jun mediated by MAP kinases.

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21 January 2018

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

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Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

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21 January 2018

Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38

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21 January 2018

Cell cycle-dependent activation of Ras.

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21 January 2018

Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38

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21 January 2018

Signal transduction by the JNK group of MAP kinases

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Activation of mitogen-activated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells

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21 January 2018

The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding

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21 January 2018

Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta

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Grasping objects: the cortical mechanisms of visuomotor transformation

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Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

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21 January 2018

The primary structure of p38 gamma: a new member of p38 group of MAP kinases

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Mitogen-activated protein kinase cascades as regulators of stress responses

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Ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in oesophageal cancer cells: involvement of the p38MAPK signalling pathway

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Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha

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Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation

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P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli.

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p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide

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p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons

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Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.

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21 January 2018

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway

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The p75(NTR) tumor suppressor induces caspase-mediated apoptosis in bladder tumor cells

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Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

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Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells

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Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells

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Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

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Dephosphorylation of cofilin is regulated through Ras and requires the combined activities of the Ras-effectors MEK and PI3K.

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IQGAP1 binds ERK2 and modulates its activity

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Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

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Notch3 signaling in vascular smooth muscle cells induces c-FLIP expression via ERK/MAPK activation. Resistance to Fas ligand-induced apoptosis

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Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase

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Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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Induction of apoptosis in starfish eggs requires spontaneous inactivation of MAPK (extracellular signal-regulated kinase) followed by activation of p38MAPK.

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10.1074/JBC.M409035200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

ResearchGate publication ID

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