(Q40528326)

21 September 2017

E17K substitution in AKT1 in prostate cancer (English)

1 reference

21 September 2017

J L Boormans

1

1 reference

21 September 2017

H Korsten

2

1 reference

21 September 2017

A C J Ziel-van der Made

3

1 reference

21 September 2017

G J L H van Leenders

4

1 reference

21 September 2017

P C M S Verhagen

5

1 reference

21 September 2017

J Trapman

6

1 reference

21 September 2017

language of work or name

English

0 references

publication date

20 April 2010

1 reference

British Journal of Cancer

21 September 2017

1 reference

21 September 2017

102

1 reference

21 September 2017

10

1 reference

21 September 2017

1491-1494

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.bjc.6605673

21 September 2017

0 references

cites work

The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

AKT1 E17 K pleckstrin homology domain mutation in urothelial carcinoma

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

A novel AKT3 mutation in melanoma tumours and cell lines

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

An integrated genomic analysis of human glioblastoma multiforme

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Detection of the transforming AKT1 mutation E17K in non-small cell lung cancer by high resolution melting

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

A new mutational AKTivation in the PI3K pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Akt-regulated pathways in prostate cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

High frequency of mutations of the PIK3CA gene in human cancers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Frequent inactivation of PTEN in prostate cancer cell lines and xenografts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

AKT1(E17K) in human solid tumours

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Frequent mutation of the PIK3CA gene in ovarian and breast cancers.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Frequent inactivation of PTEN/MMAC1 in primary prostate cancer

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869172

Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues

4 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20407443

12 December 2020

inferred from PubMed ID database lookup

An activating mutation in AKT1 in human prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20407443

12 December 2020

inferred from PubMed ID database lookup

ThePTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20407443

12 December 2020

inferred from PubMed ID database lookup

Prognostic factors for and outcome of locally advanced prostate cancer after radical prostatectomy

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605673

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.BJC.6605673

1 reference

21 September 2017

1 reference

21 September 2017

PubMed publication ID

20407443

1 reference