(Q40535274)

21 September 2017

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title

Glutathione-related enzymes, glutathione and multidrug resistance (English)

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21 September 2017

multiple drug resistance

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J A Moscow

1

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PubMed ID

7765324

21 September 2017

K H Dixon

series ordinal

2

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21 September 2017

1 January 1993

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21 September 2017

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21 September 2017

12

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21 September 2017

155-170

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21 September 2017

1-3

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https://scigraph.springernature.com/pub.10.1007/bf00744663

21 September 2017

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cites work

Purification and characterization of a novel monomeric glutathione peroxidase from rat liver

1 reference

12 December 2020

Inactivation of the genotoxic aldehyde acrolein by human glutathione transferases of classes alpha, mu, and pi.

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12 December 2020

Glutathione S-transferase and P-glycoprotein in multidrug resistant Chinese hamster cells

1 reference

12 December 2020

Alterations in glutathione and glutathione-related enzymes in a multidrug-resistant small cell lung cancer cell line

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12 December 2020

Glutathione S-transferase isoenzymes and glutathione peroxidase activity in normal and tumour samples from human lung

1 reference

12 December 2020

Metabolism of the Catharanthus alkaloids: from Streptomyces griseus to monoamine oxidase B.

1 reference

12 December 2020

Immunohistochemical Detection of P Glycoprotein, Glutathione S Transferase and DNATopoisomerase II in Human Tumors

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12 December 2020

Transformation of rat liver epithelial cells with v-H-ras or v-raf causes expression of MDR-1, glutathione-S-transferase-P and increased resistance to cytotoxic chemicals.

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12 December 2020

Effect of endogenous glutathione, superoxide dismutases, catalase, and glutathione peroxidase on adriamycin tolerance of Chinese hamster ovary cells

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12 December 2020

Human placental form of glutathione S-transferase (GST-pi) as a new immunohistochemical marker for human colonic carcinoma

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12 December 2020

Expression of human glutathione S-transferases in Saccharomyces cerevisiae confers resistance to the anticancer drugs adriamycin and chlorambucil

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12 December 2020

Phospholipid hydroperoxide glutathione peroxidase is a selenoenzyme distinct from the classical glutathione peroxidase as evident from cDNA and amino acid sequencing.

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12 December 2020

Expression of MDR1 and glutatione S transferase-π genes and chemosensitivities in human gastrointestinal cancer

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12 December 2020

Evidence for the metabolism of mitozantrone by microsomal glutathione transferases and 3-methylcholanthrene-inducible glucuronosyl transferases

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12 December 2020

Expression of P-glycoprotein and glutathione-S-transferase in recurrent lymphomas: the possible role of Epstein-Barr virus, immunophenotypes, and other predisposing factors

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12 December 2020

A new functional role for P-glycoprotein: efflux pump for benzo(alpha)pyrene in human breast cancer MCF-7 cells

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12 December 2020

Role of the glutathione-glutathione peroxidase cycle in the cytotoxicity of the anticancer quinones

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12 December 2020

Over-expression of P-glycoprotein and glutathione S-transferase pi in MCF-7 cells selected for vincristine resistance in vitro

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12 December 2020

A study of the mechanism of resistance to Adriamycin in vivo. Glutathione metabolism, P-glycoprotein expression, and drug transport

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12 December 2020

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

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12 December 2020

Glutathione, glutathione S-transferases, and related redox enzymes in Adriamycin-resistant cell lines with a multidrug resistant phenotype.

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12 December 2020

Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents

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12 December 2020

Glutathione as a determinant of cellular response to doxorubicin

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12 December 2020

Mdr1/P-glycoprotein, topoisomerase, and glutathione-S-transferase pi gene expression in primary and relapsed state adult and childhood leukaemias

1 reference

12 December 2020

Expression of plasma glutathione peroxidase in human liver in addition to kidney, heart, lung, and breast in humans and rodents

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12 December 2020

Ligandin: review and update of a multifunctional protein

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12 December 2020

Glutathione S-transferase activity and isoenzyme distribution in ovarian tumour biopsies taken before or after cytotoxic chemotherapy

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12 December 2020

Further studies on the generation of reactive oxygen species from activated anthracyclines and the relationship to cytotoxic action and cardiotoxic effects

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12 December 2020

Glutathione S-transferase and glutathione peroxidase expression in normal and tumour human tissues

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12 December 2020

A pilot study of pi-class glutathione S-transferase expression in breast cancer: correlation with estrogen receptor expression and prognosis in node-negative breast cancer

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12 December 2020

Selenium-dependent glutathione peroxidase expression is inversely related to estrogen receptor content of human breast cancer cells

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12 December 2020

Regulation of human glutathione S-transferase pi gene transcription: influence of 5'-flanking sequences and trans-activating factors which recognize AP-1-binding sites

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12 December 2020

Different drug sensitivity in two neuroblastoma cell lines established from the same patient before and after chemotherapy

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12 December 2020

Role of glutathione and dependent enzymes in anthracycline-resistant HL60/AR cells.

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12 December 2020

Potentiation of doxorubicin cytotoxicity by buthionine sulfoximine in multidrug-resistant human breast tumor cells.

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12 December 2020

Oxidative destruction of DNA by the adriamycin-iron complex.

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12 December 2020

Characterization of melphalan-glutathione adducts whose formation is catalyzed by glutathione transferases

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12 December 2020

Biochemical characterization of resistance to mitoxantrone and adriamycin in Caco-2 human colon adenocarcinoma cells: a possible role for glutathione S-transferases

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12 December 2020

Isolation of the human anionic glutathione S-transferase cDNA and the relation of its gene expression to estrogen-receptor content in primary breast cancer

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12 December 2020

Antineoplastic drug sensitivity of human MCF-7 breast cancer cells stably transfected with a human alpha class glutathione S-transferase gene

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12 December 2020

Distinct oxidoresistance phenotype of human T47D cells transfected by rat glutathione S-transferase Yc expression vectors

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12 December 2020

Selenocysteine's mechanism of incorporation and evolution revealed in cDNAs of three glutathione peroxidases

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12 December 2020

Multifactorial mechanisms associated with broad cross-resistance of ovarian carcinoma cells selected by cyanomorpholino doxorubicin

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12 December 2020

Resistance mechanisms in three human small cell lung cancer cell lines established from one patient during clinical follow-up

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12 December 2020

Primary structure of human plasma glutathione peroxidase deduced from cDNA sequences

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12 December 2020

Adriamycin-enhanced membrane lipid peroxidation in isolated rat nuclei

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12 December 2020

Reduced topoisomerase II and elevated alpha class glutathione S-transferase expression in a multidrug resistant CHO cell line highly cross-resistant to mitomycin C.

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12 December 2020

Doxorubicin resistance conferred by selective enhancement of intracellular glutathione peroxidase or superoxide dismutase content in human MCF-7 breast cancer cells

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12 December 2020

Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

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12 December 2020

Oxidized redox state of glutathione in the endoplasmic reticulum

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12 December 2020

Expression of human mu or alpha class glutathione S-transferases in stably transfected human MCF-7 breast cancer cells: effect on cellular sensitivity to cytotoxic agents

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12 December 2020

Role of the Glutathione Redox Cycle in Acquired and de Novo Multidrug Resistance

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12 December 2020

Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action.

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12 December 2020

Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines

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12 December 2020

Elevation of pi class glutathione S-transferase activity in human breast cancer cells by transfection of the GST pi gene and its effect on sensitivity to toxins.

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12 December 2020

Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones

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12 December 2020

Expression of glutathione transferase pi as a predictor for treatment results at different stages of acute nonlymphoblastic leukemia

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12 December 2020

Glutathione-s-transferase pi expression in leukaemia: a comparative analysis with mdr-1 data

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12 December 2020

Nomenclature for human glutathione transferases

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12 December 2020

Response to mitoxantrone in advanced breast cancer: correlation with expression of c-erbB-2 protein and glutathione S-transferases

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12 December 2020

Overexpression of glutathione S-transferase and elevation of thiol pools in a multidrug-resistant human colon cancer cell line

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12 December 2020

Expression of glutathione S-transferases in normal gastric mucosa and in gastric tumors

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12 December 2020

Control of expression of the human glutathione S-transferase pi gene differs from its rat orthologue

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12 December 2020

Increased expression of glutathione S-transferase gene in cis-diamminedichloroplatinum(II)-resistant variants of a Chinese hamster ovary cell line.

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12 December 2020

Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents

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12 December 2020

The role of lipid peroxidation in acute doxorubicin-induced cardiotoxicity as studied in rat isolated heart

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12 December 2020

Expression of anionic glutathione-S-transferase and P-glycoprotein genes in human tissues and tumors

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12 December 2020

Glutathione S-transferase activity of leukemic cells as a prognostic factor for response to chemotherapy in acute leukemias.

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12 December 2020

Drug resistance to cis-diamminedichloroplatinum (II) in Chinese hamster ovary cell lines transfected with glutathione S-transferase pi gene

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12 December 2020

Contribution of glutathione and glutathione-dependent enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines

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12 December 2020

An evaluation of the role of glutathione and its associated enzymes in the expression of differential sensitivities to antitumour agents shown by a range of human tumour cell lines.

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12 December 2020

Myeloperoxidase: an enzyme involved in intrinsic vincristine resistance in human myeloblastic leukemia.

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12 December 2020

Expression of drug-metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosa

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12 December 2020

cDNA sequence coding for human glutathione peroxidase

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12 December 2020

Anomalous relationship between cisplatin sensitivity and the formation and removal of platinum-DNA adducts in two human ovarian carcinoma cell lines in vitro

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12 December 2020

Glutathione S-transferase activity and isoenzyme composition in benign ovarian tumours, untreated malignant ovarian tumours, and malignant ovarian tumours after platinum/cyclophosphamide chemotherapy

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12 December 2020

Glutathione and related enzyme activity in human lung cancer cell lines

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12 December 2020

Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line

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12 December 2020

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

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12 December 2020

Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia.

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12 December 2020

Expression of MDR1 and GST-pi in human soft tissue sarcomas: relation to drug resistance and biological aggressiveness

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12 December 2020

Chlorambucil-monoglutathionyl conjugate is sequestered by human alpha class glutathione S-transferases

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12 December 2020

Adriamycin-stimulated hydroxyl radical formation in human breast tumor cells

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12 December 2020

Differential increases in glutathione S-transferase activities in a range of multidrug-resistant human tumor cell lines.

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12 December 2020

Phospholipid hydroperoxide glutathione peroxidase is the 18-kDa selenoprotein expressed in human tumor cell lines

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12 December 2020

Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion.

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12 December 2020

Overexpression of seleno-glutathione peroxidase by gene transfer enhances the resistance of T47D human breast cells to clastogenic oxidants

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12 December 2020

Effect of buthionine sulfoximine on toxicity of verapamil and doxorubicin to multidrug resistant cells and to mice

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12 December 2020

Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI

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12 December 2020

Anthracycline resistance in murine leukemic P388 cells. Role of drug efflux and glutathione related enzymes

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12 December 2020

Inhibition of glutathione synthesis augments lysis of murine tumor cells by sulfhydryl-reactive antineoplastics

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12 December 2020

Phenotypic instability of drug sensitivity in a human colon carcinoma cell line

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12 December 2020

Mechanisms involved in the development of adriamycin resistance in human leukemic cells

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12 December 2020

Expression of mdr1 and gst-pi in human breast tumours: comparison to in vitro chemosensitivity

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12 December 2020

Cross-resistance and glutathione-S-transferase-pi levels among four human melanoma cell lines selected for alkylating agent resistance

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12 December 2020

Differential effects of anthracycline drugs on rat heart and liver microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent lipid peroxidation

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12 December 2020

A mouse cDNA sequence for epididymal androgen-regulated proteins related to glutathione peroxidase

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12 December 2020

A human cDNA sequence of a novel glutathione peroxidase-related protein

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12 December 2020

Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

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12 December 2020

Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin

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12 December 2020

Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in the rat chemical hepatocarcinogenesis

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12 December 2020

Expression of glutathione S-transferase B1, B2, Mu and Pi in breast cancers and their relationship to oestrogen receptor status

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12 December 2020

Oncofetal expression of glutathione S-transferase placental form in human stomach carcinomas

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12 December 2020

Levels of expression of the mdr1 gene and glutathione S-transferase genes 2 and 3 and response to chemotherapy in multiple myeloma

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12 December 2020

Potentiation and protection of doxorubicin cytotoxicity by cellular glutathione modulation

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12 December 2020

Single GST-P positive liver cells--putative initiated hepatocytes

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12 December 2020

Glutathione peroxidase, glutathione S-transferase and glutathione reductase activities in normal and neoplastic human breast tissue

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12 December 2020

Role of glutathione and its associated enzymes in multidrug-resistant human myeloma cells.

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12 December 2020

Comparison of glutathione S-transferase activity between drug-resistant and-sensitive human tumor cells: Is glutathione S-transferase associated with multidrug resistance?

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12 December 2020

Identification of an anionic form of glutathione transferase present in many human tumors and human tumor cell lines

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12 December 2020

Adriamycin activation and oxygen free radical formation in human breast tumor cells: protective role of glutathione peroxidase in adriamycin resistance.

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12 December 2020

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12 December 2020

Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi

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12 December 2020

Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein

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12 December 2020

The spontaneous and glutathione S-transferase-mediated reaction of chlorambucil with glutathione

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12 December 2020

Prevention of doxorubicin-induced killing of MCF-7 human breast cancer cells by oxygen radical scavengers and iron chelating agents

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12 December 2020

Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transferase-pi in human lung tumors

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12 December 2020

Structure and function of the 5'-flanking sequence of the human cytosolic selenium-dependent glutathione peroxidase gene (hgpx1)

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12 December 2020

Posttranscriptional control of glutathione S-transferase pi gene expression in human breast cancer cells

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12 December 2020

Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents

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12 December 2020

Enhanced expression of glutathione S-transferases in colorectal carcinoma compared to non-neoplastic mucosa

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12 December 2020

Identifiers

DOI

10.1007/BF00744663

1 reference

PubMed ID

7765324

Dimensions Publication ID

21 September 2017

0 references

1 reference

PubMed ID

7765324