(Q40541397)

21 September 2017

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title

Therapeutic drug monitoring and individual dosing of antibiotics during sepsis : Modern or just "trendy"? (English)

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21 September 2017

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A Brinkmann

1

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21 September 2017

A C Röhr

2

1 reference

21 September 2017

A Köberer

3

1 reference

21 September 2017

T Fuchs

4

1 reference

21 September 2017

J Preisenberger

5

1 reference

21 September 2017

W A Krüger

6

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21 September 2017

O R Frey

7

1 reference

21 September 2017

13 September 2016

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Medizinische Klinik, Intensivmedizin und Notfallmedizin

21 September 2017

1 reference

https://scigraph.springernature.com/pub.10.1007/s00063-016-0213-5

21 September 2017

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cites work

Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis.

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https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Severe sepsis and septic shock

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Comparison of unit-specific and hospital-wide antibiograms: potential implications for selection of empirical antimicrobial therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Decreased Linezolid Serum Concentrations in Three Critically Ill Patients: Clinical Case Studies of a Potential Drug Interaction between Linezolid and Rifampicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Impact of compliance with infection management guidelines on outcome in patients with severe sepsis: a prospective observational multi-center study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Alveolar concentrations of piperacillin/tazobactam administered in continuous infusion to patients with ventilator-associated pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

First-line anti-infective treatment in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Society's failure to protect a precious resource: antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Optimal dosing of antibiotics in critically ill patients by using continuous/extended infusions: a systematic review and meta-analysis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Principles of antibacterial dosing in continuous renal replacement therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Vital organ blood flow during hyperdynamic sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Meropenem penetration into epithelial lining fluid in mice and humans and delineation of exposure targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Continuous infusion of beta-lactam antibiotics in severe sepsis: a multicenter double-blind, randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

A Multicenter Randomized Trial of Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Clinical outcomes with extended or continuous versus short-term intravenous infusion of carbapenems and piperacillin/tazobactam: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

A comparison of albumin and saline for fluid resuscitation in the intensive care unit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Fluid shifts have no influence on ciprofloxacin pharmacokinetics in intensive care patients with intra-abdominal sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis*.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Continuous versus intermittent infusion of vancomycin in adult patients: A systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

β-Lactam therapeutic drug monitoring in the critically ill: optimising drug exposure in patients with fluctuating renal function and hypoalbuminaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Development of resistance in wild-type and hypermutable Pseudomonas aeruginosa strains exposed to clinical pharmacokinetic profiles of meropenem and ceftazidime simulated in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Pharmacokinetics of ciprofloxacin and its penetration into bronchial secretions of mechanically ventilated patients with chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Emerging concepts in optimizing antimicrobial therapy of septic shock: speed is life but a hammer helps too

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Use of pharmacodynamic principles to inform β-lactam dosing: "S" does not always mean success

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Penetration of meropenem into epithelial lining fluid of patients with ventilator-associated pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Efficacy of high-dose nebulized colistin in ventilator-associated pneumonia caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Therapeutic Drug Monitoring of antiinfectives in intensive care medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Antimicrobial susceptibility pattern comparisons among intensive care unit and general ward Gram-negative isolates from the Meropenem Yearly Susceptibility Test Information Collection Program (USA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: a multicentre pharmacokinetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Piperacillin penetration into tissue of critically ill patients with sepsis--bolus versus continuous administration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

A systematic review on clinical benefits of continuous administration of beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

How to optimise antimicrobial prescriptions in the Intensive Care Unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Therapeutic drug monitoring of antimicrobials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Penetration of anti-infective agents into pulmonary epithelial lining fluid: focus on antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Pharmacokinetics of antibiotics in natural and experimental superficial compartments in animals and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Vancomycin therapeutic guidelines: a summary of consensus recommendations from the infectious diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Pharmacokinetic-pharmacodynamic-model-guided doripenem dosing in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Intrahospital transport of critically ill patients (excluding newborns) recommendations of the Société de Réanimation de Langue Française (SRLF), the Société Française d'Anesthésie et de Réanimation (SFAR), and the Société Française de Médecine d'Ur

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Optimization of meropenem minimum concentration/MIC ratio to suppress in vitro resistance of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Outcomes of bacteremia due to Pseudomonas aeruginosa with reduced susceptibility to piperacillin-tazobactam: implications on the appropriateness of the resistance breakpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Prolonged infusion versus intermittent boluses of β-lactam antibiotics for treatment of acute infections: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Infectious disease: childhood meningitis may be preventable if we can afford it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Using the number needed to treat to assess appropriate antimicrobial therapy as a determinant of outcome in severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

International study of the prevalence and outcomes of infection in intensive care units

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Protein binding of β-lactam antibiotics in critically ill patients: can we successfully predict unbound concentrations?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Clinical outcomes with alternative dosing strategies for piperacillin/tazobactam: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Gewebepenetration von Antibiotika

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Antimicrobial Resistance: Pharmacokinetics‐Pharmacodynamics of Antimicrobial Therapy: It’s Not Just for Mice Anymore

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00063-016-0213-5

Does Beta-lactam Pharmacokinetic Variability in Critically Ill Patients Justify Therapeutic Drug Monitoring? A Systematic Review

21 January 2018

1 reference

12 December 2020

Adequacy of early empiric antibiotic treatment and survival in severe sepsis: experience from the MONARCS trial

1 reference

12 December 2020

Glomerular hyperfiltration and albuminuria in critically ill patients

1 reference

12 December 2020

Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections

1 reference

12 December 2020

Implications of augmented renal clearance in critically ill patients

1 reference

12 December 2020

Factors associated with vancomycin nephrotoxicity in the critically ill.

1 reference

12 December 2020

Piperacillin-tazobactam for Pseudomonas aeruginosa infection: clinical implications of an extended-infusion dosing strategy

1 reference

12 December 2020

Impact of goal-oriented and model-based clinical pharmacokinetic dosing of aminoglycosides on clinical outcome: a cost-effectiveness analysis

1 reference

12 December 2020

Therapeutic Drug Monitoring of Beta-Lactam Antibiotics in Burns Patients—A One-Year Prospective Study

1 reference

12 December 2020

Aminoglycoside volume of distribution and illness severity in critically ill septic patients

1 reference

12 December 2020

The Impact of Variation in Renal Replacement Therapy Settings on Piperacillin, Meropenem, and Vancomycin Drug Clearance in the Critically Ill

1 reference

12 December 2020

Septic Acute Kidney Injury in Critically Ill Patients: Clinical Characteristics and Outcomes

1 reference

12 December 2020

Comparative Activity of Carbapenem Testing (COMPACT) study in Germany

1 reference

12 December 2020

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock

1 reference

12 December 2020

10.1007/S00063-016-0213-5

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