(Q40544614)

21 September 2017

title

Autocatalytic processing of HtrA2/Omi is essential for induction of caspase-dependent cell death through antagonizing XIAP. (English)

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21 September 2017

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Young-Mo Seong

1

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21 September 2017

Ju-Youn Choi

2

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21 September 2017

Hyo-Jin Park

3

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21 September 2017

Ki-Joong Kim

4

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21 September 2017

Sang-Gun Ahn

5

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21 September 2017

Geun-Hye Seong

6

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21 September 2017

In-Kyung Kim

7

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21 September 2017

Seongman Kang

8

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21 September 2017

Hyangshuk Rhim

9

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21 September 2017

language of work or name

English

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publication date

16 June 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

36

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21 September 2017

page(s)

37588-37596

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Sequence analysis and regulation of the htrA gene of Escherichia coli: a sigma 32-independent mechanism of heat-inducible transcription

21 September 2017

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21 January 2018

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Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

21 January 2018

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Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage

21 January 2018

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Identification and cloning of two isoforms of human high-temperature requirement factor A3 (HtrA3), characterization of its genomic structure and comparison of its tissue distribution with HtrA1 and HtrA2

21 January 2018

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Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

21 January 2018

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

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21 January 2018

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HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

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Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways

21 January 2018

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Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein

21 January 2018

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Structural and biochemical basis of apoptotic activation by Smac/DIABLO

21 January 2018

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X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

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The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Antigenicity of the region encoded by exon8 of the human serine protease, HtrA2/Omi, is associated with its protein solubility

21 January 2018

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N-terminal truncation circumvents proteolytic degradation of the human HtrA2/Omi serine protease in Escherichia coli: rapid purification of a proteolytically active HtrA2/Omi

21 January 2018

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Rapid purification and analysis of alpha-synuclein proteins: C-terminal truncation promotes the conversion of alpha-synuclein into a protease-sensitive form in Escherichia coli

21 January 2018

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Rapid purification of monomer HIV-2 Tat protein expressed in Escherichia coli

21 January 2018

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

21 January 2018

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Escherichia coli DegP protease cleaves between paired hydrophobic residues in a natural substrate: the PapA pilin

21 January 2018

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The DegP and DegQ periplasmic endoproteases of Escherichia coli: specificity for cleavage sites and substrate conformation

21 January 2018

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

21 January 2018

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

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Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2

21 January 2018

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Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

21 January 2018

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Intramembrane proteolysis controls diverse signalling pathways throughout evolution

21 January 2018

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21 January 2018

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21 January 2018

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Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide

21 January 2018

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Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M401408200

1 reference

21 September 2017

1 reference