(Q40549968)

21 September 2017

title

Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway (English)

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21 September 2017

Klaus W Wagner

1

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21 September 2017

Ingo H Engels

series ordinal

2

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21 September 2017

Quinn L Deveraux

series ordinal

3

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21 September 2017

language of work or name

English

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publication date

1 June 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

33

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21 September 2017

page(s)

35047-35052

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Apo2L/TRAIL and its death and decoy receptors

21 September 2017

cites work

1 reference

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21 January 2018

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Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

21 January 2018

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Caspases - controlling intracellular signals by protease zymogen activation

21 January 2018

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The CD95 type I/type II model

21 January 2018

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Biochemical pathways of caspase activation during apoptosis

21 January 2018

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IAP family proteins--suppressors of apoptosis

21 January 2018

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Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

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21 January 2018

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Defects in regulation of apoptosis in caspase-2-deficient mice

21 January 2018

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Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

21 January 2018

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Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

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Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

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Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

21 January 2018

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Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi

21 January 2018

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Identification of Modulators of TRAIL-Induced Apoptosis via RNAi-Based Phenotypic Screening

21 January 2018

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Role of BAX in the apoptotic response to anticancer agents

21 January 2018

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Activation and Suppression of the TRAIL Death-Receptor Pathway in Chemotherapy Sensitive and Resistant Follicular Lymphoma Cells

21 January 2018

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Involvement of mitochondria in apoptosis

21 January 2018

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TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

21 January 2018

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Defining characteristics of Types I and II apoptotic cells in response to TRAIL.

21 January 2018

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Caspase-9 can be activated without proteolytic processing

21 January 2018

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Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

21 January 2018

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Mechanisms of caspase activation

21 January 2018

1 reference

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Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment

21 January 2018

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Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M400708200

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21 September 2017

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