(Q40552928)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

author name string

Weihua Zhou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Jie Xu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Haomin Li

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Ming Xu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Wenyi Wei

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Zhenqiang Pan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Yi Sun

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

language of work or name

English

0 references

publication date

2 September 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

published in

Clinical Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

page(s)

1104-1116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5315595/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization

1 reference

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Overactivated neddylation pathway as a therapeutic target in lung cancer.

15 June 2018

1 reference

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The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1

15 June 2018

1 reference

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Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis

15 June 2018

1 reference

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Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy

15 June 2018

1 reference

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Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization

15 June 2018

1 reference

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Role of E3 ubiquitin ligases in lung cancer

15 June 2018

1 reference

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Structural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation Enzymes

15 June 2018

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15 June 2018

1 reference

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NOXA, a sensor of proteasome integrity, is degraded by 26S proteasomes by an ubiquitin-independent pathway that is blocked by MCL-1

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer

15 June 2018

1 reference

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N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Emerging roles for Lys11-linked polyubiquitin in cellular regulation.

15 June 2018

1 reference

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Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

15 June 2018

1 reference

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The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

15 June 2018

1 reference

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NEDD8 pathways in cancer, Sine Quibus Non.

15 June 2018

1 reference

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c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

15 June 2018

1 reference

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Contribution of Lysine 11-linked Ubiquitination to MIR2-mediated Major Histocompatibility Complex Class I Internalization

15 June 2018

1 reference

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Gene expression-based classification of non-small cell lung carcinomas and survival prediction

15 June 2018

1 reference

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Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells

15 June 2018

1 reference

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Validation of SAG/RBX2/ROC2 E3 ubiquitin ligase as an anticancer and radiosensitizing target

15 June 2018

1 reference

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UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex

15 June 2018

1 reference

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A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta.

15 June 2018

1 reference

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Identification of a physiological E2 module for the human anaphase-promoting complex

15 June 2018

1 reference

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

15 June 2018

1 reference

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Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

15 June 2018

1 reference

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E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

15 June 2018

1 reference

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Nonproteolytic functions of ubiquitin in cell signaling

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Restriction of Src activity by Cullin-5

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Cullin 5 regulates Dab1 protein levels and neuron positioning during cortical development

15 June 2018

1 reference

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Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity

15 June 2018

1 reference

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Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Amplification of the 3q26.3 locus is associated with progression to invasive cancer and is a negative prognostic factor in head and neck squamous cell carcinomas

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

The ubiquitin-proteasome pathway: on protein death and cell life

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Ubiquitin C-terminal hydrolase-L1 potentiates cancer chemosensitivity by stabilizing NOXA.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5315595

Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27591266

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-16-1585

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27591266%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

27591266

1 reference