(Q40569480)

English

The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus

scientific article published on 4 September 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus (English)

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

John F. Disterhoft

10

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

author name string

J Burgdorf

1

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

X-L Zhang

2

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

C Weiss

3

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

A Gross

4

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

S R Boikess

5

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

R A Kroes

6

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

M A Khan

7

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

R M Burch

8

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

C S Rex

9

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

P K Stanton

11

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

J R Moskal

12

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Europe PubMed Central

PMC publication ID

21 September 2017

language of work or name

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publication date

4 September 2015

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Europe PubMed Central

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21 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

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Europe PubMed Central

PMC publication ID

21 September 2017

308

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

202-211

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: Characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats.

1 reference

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1 reference

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Structural and molecular remodeling of dendritic spine substructures during long-term potentiation.

1 reference

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GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists

1 reference

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Rapid antidepressant effects: moving right along

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Emerging roles of metaplasticity in behaviour and disease

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GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects

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1 reference

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Glutamate-based antidepressants: 20 years on.

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22 September 2017

The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats

1 reference

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22 September 2017

An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder.

1 reference

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22 September 2017

Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression

1 reference

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22 September 2017

A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral-CA1 synapses in hippocampus

1 reference

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12 December 2020

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10.1016/J.NEUROSCIENCE.2015.09.004

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

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