(Q40573498)

21 September 2017

Expression of the hereditary hemochromatosis protein HFE increases ferritin levels by inhibiting iron export in HT29 cells (English)

1 reference

21 September 2017

Paige S Davies

1

1 reference

PubMed ID

15044462

21 September 2017

Caroline A Enns

series ordinal

2

1 reference

PubMed ID

15044462

21 September 2017

language of work or name

English

0 references

publication date

25 March 2004

1 reference

Journal of Biological Chemistry

21 September 2017

1 reference

21 September 2017

279

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21 September 2017

24

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21 September 2017

25085-25092

1 reference

Disorders of iron metabolism

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Intestinal mucosal uptake of iron and iron retention in idiopathic haemochromatosis as evidence for a mucosal abnormality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

An iron-regulated ferric reductase associated with the absorption of dietary iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Interactions of the ectodomain of HFE with the transferrin receptor are critical for iron homeostasis in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The hemochromatosis protein HFE inhibits iron export from macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Localization of iron metabolism–related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The effects of wild-type and mutant HFE expression upon cellular iron uptake in transfected human embryonic kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Evidence for the interaction of the hereditary haemochromatosis protein, HFE, with the transferrin receptor in endocytic compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Human cytomegalovirus protein US2 interferes with the expression of human HFE, a nonclassical class I major histocompatibility complex molecule that regulates iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Saturation of the endocytic pathway for the transferrin receptor does not affect the endocytosis of the epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Increased IRP1 and IRP2 RNA binding activity accompanies a reduction of the labile iron pool in HFE-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: implications for cellular iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Iron-dependent regulation of the divalent metal ion transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

A stem-loop in the 3' untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Regulating the fate of mRNA: the control of cellular iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Iron regulatory proteins and the molecular control of mammalian iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Regulation of ferritin genes and protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

The expression and regulation of the iron transport molecules hephaestin and IREG1: implications for the control of iron export from the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400537200

21 January 2018

Identifiers

DOI

10.1074/JBC.M400537200

1 reference

21 September 2017

1 reference

PubMed ID

15044462