(Q40580197)

4 February 2018

title

Cellular radiosensitivity in ataxia-telangiectasia (English)

1 reference

4 February 2018

author name string

J Thacker

series ordinal

1

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4 February 2018

publication date

1 January 1994

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4 February 2018

International Journal of Radiation Biology

published in

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4 February 2018

volume

66

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4 February 2018

page(s)

S87-S96

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4 February 2018

issue

sup6

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4 February 2018

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

cites work

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Comparison of gamma-radiation-induced accumulation of ataxia telangiectasia and control cells in G2 phase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Hypersensitivity of lymphoblastoid lines derived from ataxia telangiectasia patients to the induction of chromosomal aberrations by etoposide (VP-16).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

International Commission for Protection Against Environmental Mutagens and Carcinogens. Working paper no. 3. Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Response of radiation-sensitive human cells to defined DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Unusual levels of (ADP-ribose)n and DNA synthesis in ataxia telangiectasia cells following gamma-ray irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

The effects of ionizing radiation on cell cycle progression in ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

DNA double-strand breaks: their repair and relationship to cell killing in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Isolation and cross-sensitivity of X-ray-sensitive mutants of V79-4 hamster cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Biochemical and genetic analysis of the Chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Stable radioresistance in ataxia-telangiectasia cells containing DNA from normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Modification of deoxyribose-phosphate residues by extracts of ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

G1 arrest and cell-cycle-dependent clastogenesis in UV-irradiated human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Mutagenesis by apurinic sites in normal and ataxia telangiectasia human lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

p53 mutations increase resistance to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Creative blocks: cell-cycle checkpoints and feedback controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

The rejoining of double-strand breaks in DNA by human cell extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Inhibition and recovery of DNA synthesis in human cells after exposure to ultraviolet light

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Radiosensitivity in ataxia-telangiectasia: a new explanation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Abnormal processing of transfected plasmid DNA in cells from patients with ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Feedback controls and G2 checkpoints: fission yeast as a model system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Mutation spectrum in gamma-irradiated shuttle vector replicated in ataxia-telangiectasia lymphoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Reduced DNA topoisomerase II activity in ataxia-telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Enhanced sensitivity to camptothecin in ataxia-telangiectasia cells and its relationship with the expression of DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Cell-Cycle-Dependent Repair of Potentially Lethal Damage in the XR-1 γ-Ray-Sensitive Chinese Hamster Ovary Cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Impairment of V(D)J recombination in double-strand break repair mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Analysis of mutations caused by DNA double-strand breaks produced by a restriction enzyme in shuttle vector plasmids propagated in ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Unrepaired DNA strand breaks in irradiated ataxia telangiectasia lymphocytes suggested from cytogenetic observations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Genetic and cellular features of ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Differences in the DNA Supercoiling Response of Irradiated Cell Lines from Ataxia-telangiectasia Versus Unaffected Individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Responses of 4 X-ray-sensitive CHO cell mutants to different radiations and to irradiation conditions promoting cellular recovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Co-dominance of radioresistant DNA synthesis in a group of AT-like Chinese hamster cell mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Programmed cell death: apoptosis and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Mutagen-sensitive cell lines are obtained with a high frequency in V79 Chinese hamster cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Delayed Initiation of DNA Synthesis in Irradiated Human Diploid Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

Deficient recovery from potentially lethal radiation damage in ataxia telangiectasia and xeroderma pigmentosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09553009414551911

10.1080/09553009414551911

21 January 2018

Identifiers

DOI

1 reference

4 February 2018

PubMed ID

7836857

1 reference

4 February 2018