(Q40582287)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Telomere maintenance and cell cycle regulation in spontaneously immortalized T-cell lines from Nijmegen breakage syndrome patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

Nijmegen breakage syndrome

4 November 2019

main subject

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Krystyna Chrzanowska

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

4

Göran Roos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1

Jan Konrad Siwicki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 July 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

Experimental Cell Research

4 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

178-189

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

Eleven Polish patients with microcephaly, immunodeficiency, and chromosomal instability: the Nijmegen breakage syndrome.

4 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Genetic mapping using microcell-mediated chromosome transfer suggests a locus for Nijmegen breakage syndrome at chromosome 8q21-24.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Nijmegen breakage syndrome: consequences of defective DNA double strand break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Reconsideration of senescence, immortalization and telomere maintenance of Epstein-Barr virus-transformed human B-lymphoblastoid cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Long-term growth of human WGA-activated T-lymphocytes without feeder cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Long-term cultured IL-2-dependent T cell lines demonstrate p16(INK4a) overexpression, normal pRb/p53, and upregulation of cyclins E or D2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

A role for both RB and p53 in the regulation of human cellular senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Mechanism of telomerase induction during T cell activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Changes in telomerase activity and telomere length during human T lymphocyte senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Loss of functional pRB is not a ubiquitous feature of B-cell malignancies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Ovarian cancer cells that coexpress endogenous Rb and p16 are insensitive to overexpression of functional p16 protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Cyclin E, a redundant cyclin in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Gene amplification and overexpression of CDK4 in sporadic breast carcinomas is associated with high tumor cell proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

New link in a web of human genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Direct activation of TERT transcription by c-MYC.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Pathways governing G1/S transition and their response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

Overexpression of c-Myc alters G(1)/S arrest following ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-4827%2803%2900140-X

10.1016/S0014-4827(03)00140-X

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12799193%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference