(Q40585592)

21 September 2017

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title

Complex information processing by the transmembrane signaling system involving G proteins (English)

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21 September 2017

transmembrane protein

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information processing

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S Offermanns

1

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author name string

G Schultz

series ordinal

2

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PubMed ID

7845469

21 September 2017

language of work or name

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1 October 1994

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Naunyn-Schmiedeberg's Archives of Pharmacology

21 September 2017

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21 September 2017

350

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21 September 2017

329-338

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21 September 2017

4

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https://scigraph.springernature.com/pub.10.1007/bf00178947

21 September 2017

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cites work

Interaction between G-protein beta and gamma subunit types is selective

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12 December 2020

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

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12 December 2020

Molecular and functional diversity of mammalian Gs-stimulated adenylyl cyclases.

1 reference

12 December 2020

Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases in

1 reference

12 December 2020

Type II adenylylcyclase integrates coincident signals from Gs, Gi, and Gq.

1 reference

12 December 2020

Purification of four forms of the beta gamma subunit complex of G proteins containing different gamma subunits

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12 December 2020

Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells

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12 December 2020

Direct regulation of cardiac Ca2+ channels by G proteins: neither proven nor necessary?

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12 December 2020

Alternative splicing directs the expression of two D2 dopamine receptor isoforms.

1 reference

12 December 2020

Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs

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12 December 2020

Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits

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12 December 2020

Structure and mechanism of the G protein-coupled receptor kinases.

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12 December 2020

G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma

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12 December 2020

Agonist-sensitive binding of a photoreactive GTP analog to a G-protein alpha-subunit in membranes of HL-60 cells

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12 December 2020

G protein diversity is increased by associations with a variety of gamma subunits

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12 December 2020

The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase

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12 December 2020

A1 adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins Gi1, Gi2, and Go.

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12 December 2020

New insights on mammalian phospholipase A2(s); comparison of arachidonoyl-selective and -nonselective enzymes.

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12 December 2020

Gz-mediated hormonal inhibition of cyclic AMP accumulation

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12 December 2020

Two distinct Gi-proteins mediate formyl peptide receptor signal transduction in human leukemia (HL-60) cells.

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12 December 2020

mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells

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12 December 2020

Selectivity of the effects of guanosine-5'-O-(2-thiodiphosphate) on agonist inhibition of the M-current in amphibian sympathetic neurons

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12 December 2020

Molecular machines integrate coincident synaptic signals

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12 December 2020

Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases

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12 December 2020

Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents

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12 December 2020

Thyrotropin activates both the cyclic AMP and the PIP2 cascades in CHO cells expressing the human cDNA of TSH receptor

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12 December 2020

Activation of phospholipase C beta 4 by heterotrimeric GTP-binding proteins.

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12 December 2020

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12 December 2020

Signal integration in the nervous system: adenylate cyclases as molecular coincidence detectors

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12 December 2020

Specificity of receptor-G protein interactions. Discrimination of Gi subtypes by the D2 dopamine receptor in a reconstituted system.

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12 December 2020

Expression of two human beta-adrenergic receptors in Escherichia coli: functional interaction with two forms of the stimulatory G protein

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12 December 2020

Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells

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12 December 2020

Splice variants of the alpha subunit of the G protein Gs activate both adenylyl cyclase and calcium channels

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12 December 2020

A family of metabotropic glutamate receptors

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12 December 2020

Ionic Channels and Their Regulation by G Protein Subunits

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12 December 2020

An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover

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12 December 2020

Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells

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12 December 2020

G protein-coupled mechanisms and nervous signaling

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12 December 2020

Structure and function of receptors coupled to G proteins

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12 December 2020

Selectivity of the .beta.-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant .alpha. subunits in reconstituted phospholipid vesicles

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12 December 2020

Activation by G protein beta gamma subunits of agonist- or light-dependent phosphorylation of muscarinic acetylcholine receptors and rhodopsin

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12 December 2020

Retinal rods and cones have distinct G protein beta and gamma subunits

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12 December 2020

Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. III. Coupling of alpha 2-adrenergic receptor subtypes in a cell type-specific manner

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12 December 2020

The human thyrotropin receptor activates G-proteins Gs and Gq/11

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12 December 2020

Expanding horizons for receptors coupled to G proteins: diversity and disease

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12 December 2020

New roles for G-protein beta gamma-dimers in transmembrane signalling.

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12 December 2020

Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel

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12 December 2020

The importance of G-protein beta lambda subunits

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12 December 2020

Multiple Gi protein subtypes regulate a single effector mechanism

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12 December 2020

Phosducin is a protein kinase A-regulated G-protein regulator

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12 December 2020

Analysis of Gz alpha by site-directed mutagenesis. Sites and specificity of protein kinase C-dependent phosphorylation

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12 December 2020

G protein beta gamma subunits. Simplified purification and properties of novel isoforms

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12 December 2020

Different beta-subunits determine G-protein interaction with transmembrane receptors

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12 December 2020

Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphoinositide breakdown and Ca2+ mobilization. Studies with the cloned murine luteinizing hormone receptor expressed in L cells

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12 December 2020

Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor

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12 December 2020

Gi-2 is at the centre of an active phosphorylation/dephosphorylation cycle in hepatocytes: the fine-tuning of stimulatory and inhibitory inputs into adenylate cyclase in normal and diabetic states

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12 December 2020

Agonist binding to rat brain somatostatin receptors alters the interaction of the receptors with guanine nucleotide-binding regulatory proteins.

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12 December 2020

Asymmetrical distribution of G-proteins among the apical and basolateral membranes of rat enterocytes

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12 December 2020

Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits

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12 December 2020

G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets

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12 December 2020

Specificity of G protein beta and gamma subunit interactions.

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12 December 2020

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12 December 2020

Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxin-insensitive manner.

1 reference

12 December 2020

Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase

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12 December 2020

Mechanism of activation of A2 adenosine receptors. II. A restricted collision-coupling model of receptor-effector interaction

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12 December 2020

Model systems for the study of seven-transmembrane-segment receptors

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12 December 2020

Cloning and expression of a novel mouse somatostatin receptor (SSTR2B).

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12 December 2020

Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein

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12 December 2020

The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system

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12 December 2020

Regulation of phospholipase C by G proteins

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12 December 2020

Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cells

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12 December 2020

Diversity of G proteins in signal transduction

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12 December 2020

Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cel

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12 December 2020

Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits

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12 December 2020

Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction

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12 December 2020

The G protein connection: molecular basis of membrane association.

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12 December 2020

Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

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12 December 2020

Two alpha subunits of the Gq class of G proteins stimulate phosphoinositide phospholipase C-beta 1 activity

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12 December 2020

Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1

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12 December 2020

Dual regulation by G proteins of agonist-dependent phosphorylation of muscarinic acetylcholine receptors.

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12 December 2020

Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf

1 reference

12 December 2020

Factors determining the specificity of signal transduction by guanine nucleotide-binding protein-coupled receptors. I. Coupling of alpha 2-adrenergic receptor subtypes to distinct G-proteins

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12 December 2020

G0 is a major growth cone protein subject to regulation by GAP-43.

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12 December 2020

Effector coupling mechanisms of the cloned 5-HT1A receptor

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12 December 2020

Cloned human neuropeptide Y receptor couples to two different second messenger systems

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12 December 2020

Pertussis toxin-sensitive G proteins are transported toward synaptic terminals by fast axonal transport

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12 December 2020

Inhibition of adenylyl cyclase by Gi alpha

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12 December 2020

A third form of the G protein beta subunit. 1. Immunochemical identification and localization to cone photoreceptors

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12 December 2020

Receptor-effector coupling by G proteins

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12 December 2020

The G protein-gated atrial K+ channel is stimulated by three distinct Gi alpha-subunits

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12 December 2020

Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits

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12 December 2020

Photoaffinity labeling of two rat liver plasma membrane proteins with [32P]gamma-azidoanilido GTP in response to vasopressin. Immunologic identification as alpha subunits of the Gq class of G proteins

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12 December 2020

Involvement of pertussis toxin-sensitive G-proteins in the hormonal inhibition of dihydropyridine-sensitive Ca2+ currents in an insulin-secreting cell line (RINm5F).

1 reference

12 December 2020

Compartmentation of receptors and guanine nucleotide-binding proteins in NG108-15 cells: lack of cross-talk in agonist binding among the alpha 2-adrenergic, muscarinic, and opiate receptors.

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12 December 2020

Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C

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12 December 2020

Lateral motion of beta receptors in membranes of cultured liver cells

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12 December 2020

Receptor-to-effector signaling through G proteins: roles for beta gamma dimers as well as alpha subunits

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12 December 2020

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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12 December 2020

Rapid beta-adrenergic modulation of cardiac calcium channel currents by a fast G protein pathway

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12 December 2020

Role of G Proteins in Calcium Channel Modulation

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12 December 2020

Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits

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12 December 2020

Covalent modifications of G-proteins

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12 December 2020

Evolution of the mammalian G protein alpha subunit multigene family

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12 December 2020

A recombinant calcitonin receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+/inositol phosphate signaling pathways

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12 December 2020

Reverse intrinsic activity of antagonists on G protein-coupled receptors

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12 December 2020

Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase.

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12 December 2020

Differential signal transduction by five splice variants of the PACAP receptor

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12 December 2020

Lipid modifications of G proteins

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12 December 2020

Coupling of expressed alpha 1B- and alpha 1D-adrenergic receptor to multiple signaling pathways is both G protein and cell type specific

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12 December 2020

Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins

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12 December 2020

Lateral mobility of proteins and lipids in the red cell membrane and the activation of adenylate cyclase by beta-adrenergic receptors

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12 December 2020

The active role of beta gamma in signal transduction

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12 December 2020

Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2

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12 December 2020

Specific interaction with rhodopsin is dependent on the gamma subunit type in a G protein

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12 December 2020

The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family

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12 December 2020

Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins

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12 December 2020

Molecular mechanism of visual transduction

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12 December 2020

Identifiers

DOI

10.1007/BF00178947

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21 September 2017

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PubMed ID

7845469