(Q40590712)

21 September 2017

title

Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion (English)

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21 September 2017

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Sarah E Cross

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Isabelle Leclerc

object named as

Isabelle Leclerc

1

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Gabriela da Silva Xavier

object named as

Gabriela da Silva Xavier

3

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Guy A. Rutter

9

object named as

Guy A Rutter

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21 September 2017

author name string

Wolfram W Woltersdorf

2

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21 September 2017

Rebecca L Rowe

4

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21 September 2017

Greg S Korbutt

6

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21 September 2017

Ray V Rajotte

7

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21 September 2017

Richard Smith

8

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21 September 2017

publication date

10 February 2004

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American Journal of Physiology - Endocrinology and Metabolism

21 September 2017

published in

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21 September 2017

volume

286

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21 September 2017

issue

6

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21 September 2017

page(s)

E1023-31

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Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis

21 September 2017

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The ABCs of ATP-sensitive potassium channels: more pieces of the puzzle

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Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

21 January 2018

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21 January 2018

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Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

21 January 2018

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Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression

21 January 2018

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Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure.

21 January 2018

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Pharmacologic therapy for type 2 diabetes mellitus

21 January 2018

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Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.

21 January 2018

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AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes

21 January 2018

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Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

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Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

21 January 2018

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Triggering and amplifying pathways of regulation of insulin secretion by glucose

21 January 2018

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Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

21 January 2018

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Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

21 January 2018

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AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats

21 January 2018

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Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

21 January 2018

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21 January 2018

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Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.

21 January 2018

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The adipoinsular axis: effects of leptin on pancreatic beta-cells

21 January 2018

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5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle

21 January 2018

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AMP- and stress-activated protein kinases: key regulators of glucose-dependent gene transcription in mammalian cells?

21 January 2018

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Hepatocyte nuclear factor-4alpha involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase

21 January 2018

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Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in type 2 diabetes mellitus: the 10-year follow-up of the Belfast Diet Study.

21 January 2018

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Effects of glibenclamide and metformin (alone or in combination) on insulin release from isolated human pancreatic islets

21 January 2018

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Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats

21 January 2018

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

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Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

21 January 2018

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21 January 2018

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Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis

21 January 2018

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L-type calcium channels in insulin-secreting cells: biochemical characterization and phosphorylation in RINm5F cells.

21 January 2018

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AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release.

21 January 2018

1 reference

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Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

21 January 2018

1 reference

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5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics

21 January 2018

1 reference

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Regulation of fatty acid homeostasis in cells: novel role of leptin

21 January 2018

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Hypoxia induces vascular endothelial growth factor gene and protein expression in cultured rat islet cells

21 January 2018

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Subcellular distribution of metformin in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00532.2003

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00532.2003

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00532.2003

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

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Role of AMP-activated protein kinase in mechanism of metformin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00532.2003

Acute stimulation of glucose metabolism in mice by leptin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00532.2003

10.1152/AJPENDO.00532.2003

21 January 2018

Identifiers

DOI

1 reference

21 September 2017

1 reference