(Q40591949)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11745237%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

A Phase I study of infusional vinblastine in combination with the P-glycoprotein antagonist PSC 833 (valspodar) (English)

1 reference

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5 December 2019

1 reference

2

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5 December 2019

Rob Robey

11

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5 December 2019

1

S Bates

1 reference

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5 December 2019

14

T Fojo

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5 December 2019

author name string

B Meadows

3

1 reference

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5 December 2019

S Bakke

4

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5 December 2019

P Choyke

5

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5 December 2019

M Merino

6

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5 December 2019

B Goldspiel

7

1 reference

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5 December 2019

I Chico

8

1 reference

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5 December 2019

T Smith

9

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5 December 2019

C Chen

10

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5 December 2019

R Bergan

12

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5 December 2019

W D Figg

13

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5 December 2019

language of work or name

English

0 references

publication date

1 September 2001

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5 December 2019

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5 December 2019

volume

92

1 reference

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5 December 2019

issue

6

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5 December 2019

page(s)

1577-1590

1 reference

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SDZ PSC 833, a non-immunosuppressive cyclosporine: its potency in overcoming P-glycoprotein-mediated multidrug resistance of murine leukemia

5 December 2019

cites work

1 reference

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P-glycoprotein expression and schedule dependence of adriamycin cytotoxicity in human colon carcinoma cell lines

21 January 2018

1 reference

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Phase II trials of 5-day vinblastine infusion (NSC 49842), L-alanosine (NSC 153353), acivicin (NSC 163501), and aminothiadiazole (NSC 4728) in patients with recurrent or metastatic renal cell carcinoma

21 January 2018

1 reference

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Future perspectives for the development of P-glycoprotein modulators

21 January 2018

1 reference

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The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions

21 January 2018

1 reference

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Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

21 January 2018

1 reference

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Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

21 January 2018

1 reference

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Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

21 January 2018

1 reference

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Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

21 January 2018

1 reference

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Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

21 January 2018

1 reference

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P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0142%2820010915%2992%3A6%3C1577%3A%3AAID-CNCR1484%3E3.0.CO%3B2-H

Initial pharmacokinetics and bioavailability of PSC 833, a P-glycoprotein antagonist

21 January 2018

1 reference

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Intrinsic drug resistance in primary and metastatic renal cell carcinoma

21 January 2018

1 reference

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Phase I trial of etoposide with cyclosporine as a modulator of multidrug resistance

21 January 2018

1 reference

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Optimizing the absorption of valspodar, a P-glycoprotein modulator, Part I: Selecting an oral formulation and exploring its clinical pharmacokinetics/dynamics.

21 January 2018

1 reference

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Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP.

21 January 2018

1 reference

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Phase I study of paclitaxel in combination with a multidrug resistance modulator, PSC 833 (Valspodar), in refractory malignancies.

21 January 2018

1 reference

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Phase I dose-finding and pharmacokinetic study of paclitaxel and carboplatin with oral valspodar in patients with advanced solid tumors

21 January 2018

1 reference

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Phase I study of infusional paclitaxel in combination with the P-glycoprotein antagonist PSC 833.

21 January 2018

1 reference

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Pharmacological considerations in the modulation of multidrug resistance

21 January 2018

1 reference

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The erythromycin breath test predicts the clearance of midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0142%2820010915%2992%3A6%3C1577%3A%3AAID-CNCR1484%3E3.0.CO%3B2-H

Modulation of vinblastine resistance with cyclosporine: a phase I study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1097-0142%2820010915%2992%3A6%3C1577%3A%3AAID-CNCR1484%3E3.0.CO%3B2-H

Optimizing the absorption of valspodar, a P-glycoprotein modulator, Part II: Quantifying its pharmacokinetic variability and refining the bioavailability estimate

21 January 2018

1 reference

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Phase I study of mitoxantrone plus etoposide with multidrug blockade by SDZ PSC-833 in relapsed or refractory acute myelogenous leukemia

21 January 2018

1 reference

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In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients

21 January 2018

1 reference

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Are the major effects of P-glycoprotein modulators due to altered pharmacokinetics of anticancer drugs?

21 January 2018

1 reference

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10.1002/1097-0142(20010915)92:6<1577::AID-CNCR1484>3.0.CO;2-H

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11745237%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference