(Q40594132)

21 September 2017

1 reference

title

Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis (English)

1 reference

21 September 2017

J Ashby

1

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21 September 2017

A Brady

2

1 reference

21 September 2017

C R Elcombe

3

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21 September 2017

B M Elliott

4

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21 September 2017

J Ishmael

5

1 reference

21 September 2017

J Odum

6

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21 September 2017

J D Tugwood

7

1 reference

21 September 2017

S Kettle

8

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21 September 2017

I F Purchase

9

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21 September 2017

publication date

1 November 1994

1 reference

Human & Experimental Toxicology

21 September 2017

published in

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21 September 2017

volume

13 Suppl 2

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21 September 2017

page(s)

S1-117

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Too many rodent carcinogens: mitogenesis increases mutagenesis

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Preneoplastic lesions in rodent kidney induced spontaneously or by non-genotoxic agents: predictive nature and comparison to lesions induced by genotoxic carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Thyroid follicular cell carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Early responses of the liver of B6C3F1 mice to the hepatocarcinogen oxazepam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Early indicators of bladder carcinogenesis produced by non-genotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Early indicators of exocrine pancreas carcinogenesis produced by non-genotoxic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Evidence for and possible mechanisms of non-genotoxic carcinogenesis in the rodent thyroid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Species differences in response to trichloroethylene. II. Biotransformation in rats and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The role of trichloracetic acid and peroxisome proliferation in the differences in carcinogenicity of perchloroethylene in the mouse and rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Interaction of some peroxisome proliferators with the mouse liver peroxisome proliferator-activated receptor (PPAR): a molecular modelling and quantitative structure-activity relationship (QSAR) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

An assessment of the in vitro hepatocyte micronucleus assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

DNA damage and oxygen radical toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The regulation of epidermal hyperplastic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Promotion of epidermal carcinogenesis by repeated damage to mouse skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Experimental Production of Malignant Growths by Simple Chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Rapid growth of preneoplastic lesions in hepatocarcinogen-Sensitive C3H/HeJ male mice relative to C57BL/6J male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Hepatocellular DNA synthesis in rats given peroxisome proliferating agents: comparison of WY-14,643 to clofibric acid, nafenopin and LY171883.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Clonal adaptation during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Effects of methapyrilene on DNA synthesis in mice and rats following continuous dietary exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The chronic hepatic or renal toxicity of di(2-ethylhexyl) phthalate, acetaminophen, sodium barbital, and phenobarbital in male B6C3F1 mice: autoradiographic, immunohistochemical, and biochemical evidence for levels of DNA synthesis not associated wi

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The steroid and thyroid hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Identification of cytosolic peroxisome proliferator binding protein as a member of the heat shock protein HSP70 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Interaction of LY171883 and other peroxisome proliferators with fatty-acid-binding protein isolated from rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of fatty acid binding protein by peroxisome proliferators in primary hepatocyte cultures and its relationship to the induction of peroxisomal beta-oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Species differences in response to trichloroethylene. I. Pharmacokinetics in rats and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The c-erb-A protein is a high-affinity receptor for thyroid hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The c-erb-A gene encodes a thyroid hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): species differences and possible mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

A genetic model for colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Analysis of activated protooncogenes in B6C3F1 mouse liver tumors induced by ciprofibrate, a potent peroxisome proliferator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Ras mutations in methylclofenapate-induced B6C3F1 and C57BL/10J mouse liver tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Growth, regression and cell death in rat liver as related to tissue levels of the hepatomitogen cyproterone acetate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction, immunochemical identity and immunofluorescence localization of an 80 000-molecular-weight peroxisome-proliferation-associated polypeptide (polypeptide PPA-80) and peroxisomal enoyl-CoA hydratase of mouse liver and renal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Studies on the hepatic effects of orally administered di-(2-ethylhexyl) phthalate in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The effect of dehydroepiandrosterone acetate on liver peroxisomal enzyme activities of male and female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of fatty acid beta-oxidation and peroxisome proliferation in the liver of rhesus monkeys by DL-040, a new hypolipidemic agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of peroxisome proliferation in rat liver by dietary treatment with 2,2,4,4,6,8,8-heptamethylnonane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Genetic differences in enzymes associated with peroxisome proliferation and hydrogen peroxide metabolism in inbred mouse strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Hypolipidemic effect and enhancement of peroxisomal beta-oxidation in the liver of rats by sodium-(E)-3-(4-(3-pyridylmethyl)phenyl)-2-methyl propenoate (OKY-1581), a potent inhibitor of TxA2 synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The effect of tridiphane (2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane) on hepatic epoxide-metabolizing enzymes: indications of peroxisome proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of peroxisome proliferation and hepatic tumours in C57BL/6N mice by ciprofibrate, a hypolipidaemic compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-α-p-chlorophenoxyisobutyrate (clofibrate) in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chronic toxicity of 2,4-dichlorophenoxyacetic acid in rats and dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The carcinogenicity of dietary di(2-ethylhexyl) phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

In vivo studies on the mechanism of di(2-ethylhexyl)phthalate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Various short-term assays and two long-term studies with the plasticizer di(2-ethylhexyl)phthalate in the Syrian golden hamster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Quantitative analysis of hepatocellular lesions induced by di(2-ethylhexyl)phthalate in F-344 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Carcinogenicity of general-purpose phthalates: structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Effects of chronic treatment with the leukotriene D4-antagonist compound LY171883 on B6C3F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Malignant Tumors in Rats Fed Nafenopin, a Hepatic Peroxisome Proliferator 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Carcinogenicity study of trichloroethylene by longterm inhalation in three animal species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Inhalation carcinogenicity of trichloroethylene in mice and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Bioassay of 2, 4, 5-trichlorophenoxyacetic acid for carcinogenicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Microsomal cytochrome P-452 induction and peroxisome proliferation by hypolipidaemic agents in rat liver. A mechanistic inter-relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Possible mechanisms in hepatocarcinogenesis by the peroxisome proliferator di(2-ethylhexyl)phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of cytosolic and microsomal epoxide hydrolases and proliferation of peroxisomes and mitochondria in mouse liver after dietary exposure to p-chlorophenoxyacetic acid, 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Three Hypolipidemic Drugs Increase Hepatic Palmitoyl-Coenzyme A Oxidation in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

In vitro steady-state levels of hydrogen peroxide after exposure of male F344 rats and female B6C3F1 mice to hepatic peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Evaluation of the genetic toxicity of the peroxisome proliferator and carcinogen methyl clofenapate, including assays using Muta Mouse and Big Blue transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, Syrian hamster, guinea pig, and marmoset

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Study of the mutagenic activity of 6 hepatotoxic pharmaceutical drugs in the Salmonella typhimurium microsome test, and the HGPRT and Na+/K+ ATPase system in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of sister chromatid exchanges by the peroxisome proliferators 2,4-D, MCPA, and clofibrate in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Morphological transformation and catalase activity of Syrian hamster embryo cells treated with hepatic peroxisome proliferators, TPA and nickel sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Lack of DNA damage or lipid peroxidation measured in vivo in the rat liver following treatment with peroxisomal proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Genotoxic effects of selected peroxisome proliferators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Effect of peroxisome proliferator carcinogens on unscheduled DNA synthesis in rat hepatocytes determined by autoradiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Structure-activity relationships in the rat hepatocyte DNA-repair test for 300 chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Failure of the peroxisome proliferator WY-14,643 to induce unscheduled DNA synthesis in rat hepatocytes following in vivo treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Analysis of DNA strand breaks induced in rodent liver in vivo, hepatocytes in primary culture, and a human cell line by chlorinated acetic acids and chlorinated acetaldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Genotoxicity of organic chemicals frequently found in the air of mobile homes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Activities of chlorinated ethane and ethylene compounds in the Salmonella/rat microsome mutagenesis and rat hepatocyte/DNA repair assays under vapor phase exposure conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Evaluation of the SOS chromotest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Genetic effects of chlorinated ethylenes in the yeast Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chlorinated ethylenes: their metabolism and effect on DNA repair in rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenicity testing of di(2-ethylhexyl)phthalate and related chemicals in Salmonella.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Assessment of the mutagenicity of phthalate esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Recent progress in safety evaluation studies on plasticizers and plastics and their controlled use in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chemical mutagenesis testing in Drosophila. III. Results of 48 coded compounds tested for the National Toxicology Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Review of the hepatic response to hypolipidaemic drugs in rodents and assessment of its toxicological significance to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Phthalate ester testing in the National Toxicology Program's environmental mutagenesis test development program

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Non-mutagenicity of 4 metabolites of di(2-ethylhexyl)phthalate (DEHP) and 3 structurally related derivatives of di(2-ethylhexyl)adipate (DEHA) in the Salmonella mutagenicity assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chemical mutagenesis testing in Drosophila. V. Results of 53 coded compounds tested for the National Toxicology Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Dominant lethal mutations and antifertility effects of di-2-ethylhexyl adipate and diethyl adipate in male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenic/carcinogenic potential of DEHP and MEHP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenicity evaluation of phthalic acid esters and metabolites in Salmonella typhimurium cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenicity study of nine monoalkyl phthalates and a dialkyl phthalate using Salmonella typhimurium and Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Lack of genotoxic activity of di(2-ethylhexyl)phthalate (DEHP) in rat and human hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Effect of di(2-ethylhexyl) phthalate on DNA repair and lipid peroxidation in rat hepatocytes and on metabolic cooperation in Chinese hamster V-79 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Tumor-promoting effects of di(2-ethylhexyl)phthalate in JB6 mouse epidermal cells and mouse skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chemical mutagenesis testing in Drosophila. IV. Results of 45 coded compounds tested for the National Toxicology Program.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chemical mutagenesis testing in Drosophila. VII. Results of 22 coded compounds tested in larval feeding experiments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Carcinogenicity of trichloroethylene: fact or artifact?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenicity of inhalation anaesthetics: trichloroethylene, divinyl ether, nitrous oxide and cyclopropane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

A study of the mutagenicity of anesthetics and their metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Conditions affecting the mutagenicity of trichloroethylene in Salmonella

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

An association between mutagenicity of the Ara test of Salmonella typhimurium and carcinogenicity in rodents for 16 halogenated aliphatic hydrocarbons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

In vivo and in vitro mutagenicity studies of a possible carcinogen, trichloroethylene, and its two stabilizers, epichlorohydrin and 1,2-epoxybutane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mutagenic and lethal effects of α-benzene hexachloride, dibutyl phthalate and trichloroethylene in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The mutagenic activity of selected compounds at the TK locus: rodent vs. human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Application and Results of Whole-Body Autoradiography in Distribution Studies of Organic Solvents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

In vitro transformation of BALB/c-3T3 cells by chlorinated ethanes and ethylenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Transforming activities of trichloroethylene and proposed industrial alternatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The morphological transformation of Syrian hamster embryo cells by chemicals reportedly nonmutagenic to Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: testing of 24 compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Trichloroethylene vapours do not produce dominant lethal mutations in male mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Performance of 133 compounds in the lambda prophage induction endpoint of the Microscreen assay and a comparison with S. typhimurium mutagenicity and rodent carcinogenicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. III. Results with 27 chemicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of mutagenesis and transformation in BALB/c-3T3 clone A31-1 cells by diverse chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Chemical enhancement of SA7 virus transformation of hamster embryo cells: evaluation by interlaboratory testing of diverse chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

A rapid in vitro assay for carcinogenicity of chemical substances in mammalian cells utilizing an attachment-independence endpoint. 2 - Assay validation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Long-term effects of peroxisome proliferators on the balance between hydrogen peroxide-generating and scavenging capacities in the liver of Fischer-344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Long-term effects of hypolipidemic peroxisome proliferator administration on hepatic hydrogen peroxide metabolism in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The effect of clofibrate on vitamin E concentrations in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Induction of peroxisomes by treatment with perfluorooctanoate does not increase rates of H2O2 production in intact liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Increased hydroxyl radical production in liver peroxisomal fractions from rats treated with peroxisome proliferators

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Lack of induction of hepatic DNA damage on long-term administration of peroxisome proliferators in male F-344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Development of hepatocellular carcinomas and increased peroxisomal fatty acid beta-oxidation in rats fed [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (Wy-14,643) in the semipurified diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Formation of 5-hydroxymethyl-2'-deoxyuridine in hepatic DNA of rats treated with gamma-irradiation, diethylnitrosamine, 2-acetylaminofluorene or the peroxisome proliferator ciprofibrate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to carcinogenesis and nuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Assay of 1-nitropropane, 2-nitropropane, 1-azoxypropane and 2-azoxypropane for carcinogenicity by gavage in Sprague-Dawley rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Correlation of hepatocellular proliferation with hepatocarcinogenicity induced by the mutagenic noncarcinogen:carcinogen pair--2,6- and 2,4-diaminotoluene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

A proposed role for silicates and protein in the proliferative effects of saccharin on the male rat urothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Studies of early hepatocellular proliferation and peroxisomal proliferation in Sprague-Dawley rats treated with tumorigenic doses of clofibrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Mitogenic stimulation of hepatocellular proliferation in rodents following 1,4-dichlorobenzene administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Evaluation of genotoxicity, pathological lesions, and cell proliferation in livers of rats and mice treated with furan

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

The effects of methapyrilene hydrochloride on hepatocarcinogenicity and pentobarbital-induced sleeping time in rats and mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

NATURE OF THE HEPATOMEGALIC EFFECT PRODUCED BY ETHYL-CHLOROPHENOXY-ISOBUTYRATE IN THE RAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719401300201

10.1177/096032719401300201

21 January 2018

Identifiers

DOI

1 reference

21 September 2017

1 reference