(Q40595894)

English

Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide

scientific article published on 23 January 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 September 2017

Alpha-synuclein up-regulation and aggregation during MPP+-induced apoptosis in neuroblastoma cells: intermediacy of transferrin receptor iron and hydrogen peroxide (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

1 reference

ChEBI release 2020-05-28

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based on heuristic

inferred from title

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based on heuristic

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author name string

Shasi V Kalivendi

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Sonya Cunningham

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Srigiridhar Kotamraju

3

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Joy Joseph

4

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Cecilia J Hillard

5

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

B Kalyanaraman

6

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

language of work or name

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publication date

23 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 September 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

15240-15247

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Ironing out Parkinson's disease: is therapeutic treatment with iron chelators a real possibility?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Neurochemical findings in the MPTP model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

1-Methyl-4-phenylpyridinium (MPP+)-induced apoptosis and mitochondrial oxidant generation: role of transferrin-receptor-dependent iron and hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

N-acetyl-L-cysteine inhibits 26S proteasome function: implications for effects on NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

alpha-Synuclein affects the MAPK pathway and accelerates cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Brain iron pathways and their relevance to Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Iron misregulation in the brain: a primary cause of neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Iron in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Doxorubicin-induced apoptosis: implications in cardiotoxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

The essential role of mitochondria in the biogenesis of cellular iron-sulfur proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: role of transferrin receptor-dependent iron uptake in apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Effects of oxidative and nitrative challenges on alpha-synuclein fibrillogenesis involve distinct mechanisms of protein modifications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Proteasome inhibitors block Ras/ERK signaling pathway resulting in the downregulation of Fas ligand expression during activation-induced cell death in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312497200

21 January 2018

Identifiers

10.1074/JBC.M312497200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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