(Q40601308)

English

Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways

scientific article published on January 2004

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways (English)

1 reference

Europe PubMed Central

21 September 2017

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Hee Yong Chung

11

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author name string

Jung-A Choi

1

1 reference

Europe PubMed Central

21 September 2017

Moon-Taek Park

2

1 reference

Europe PubMed Central

21 September 2017

Chang-Mo Kang

3

1 reference

Europe PubMed Central

21 September 2017

Hong-Duck Um

4

1 reference

Europe PubMed Central

21 September 2017

Sangwoo Bae

5

1 reference

Europe PubMed Central

21 September 2017

Kee-Ho Lee

6

1 reference

Europe PubMed Central

21 September 2017

Tae-Hwan Kim

7

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Europe PubMed Central

21 September 2017

Jae-Hong Kim

8

1 reference

Europe PubMed Central

21 September 2017

Chul-Koo Cho

9

1 reference

Europe PubMed Central

21 September 2017

Yun-Sil Lee

10

1 reference

Europe PubMed Central

21 September 2017

Su-Jae Lee

12

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Europe PubMed Central

21 September 2017

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publication date

1 January 2004

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Europe PubMed Central

21 September 2017

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Europe PubMed Central

21 September 2017

23

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Europe PubMed Central

21 September 2017

9-20

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Europe PubMed Central

21 September 2017

1

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Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206982

0 references

Studies on the Influence of the Presence of an ActivatedRasOncogene on thein VitroRadiosensitivity of Human Mammary Epithelial Cells

1 reference

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Caspases induce cytochrome c release from mitochondria by activating cytosolic factors

1 reference

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21 January 2018

p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells.

1 reference

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21 January 2018

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

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21 January 2018

Implication of the small GTPase Rac1 in the apoptosis induced by UV in Rat-2 fibroblasts

1 reference

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21 January 2018

Oncogenic Ras-induced proliferation requires autocrine fibroblast growth factor 2 signaling in skeletal muscle cells

1 reference

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21 January 2018

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

1 reference

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21 January 2018

Regulated targeting of BAX to mitochondria.

1 reference

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21 January 2018

Isotype-specific functions of Raf kinases

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21 January 2018

Ras effectors and their role in mitogenesis and oncogenesis

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Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells

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21 January 2018

Apoptosis induction by T-2 toxin: activation of caspase-9, caspase-3, and DFF-40/CAD through cytosolic release of cytochrome c in HL-60 cells

1 reference

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21 January 2018

Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

1 reference

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21 January 2018

Differential activation of the Rac pathway by Ha-Ras and K-Ras

1 reference

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21 January 2018

Oncogenic Ki-ras but not oncogenic Ha-ras blocks integrin beta1-chain maturation in colon epithelial cells

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21 January 2018

Ras-induced cellular events (review)

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7 January 2021

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Loss of G2/M arrest correlates with radiosensitization in two human sarcoma cell lines with mutant p53.

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7 January 2021

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Mutant K-ras enhances apoptosis in embryonic stem cells in combination with DNA damage and is associated with increased levels of p19(ARF).

1 reference

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7 January 2021

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Increasing complexity of Ras signaling.

1 reference

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7 January 2021

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Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells

1 reference

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7 January 2021

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Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium

1 reference

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7 January 2021

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Ras proteins in the control of the cell cycle and cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206982

7 January 2021

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Protection of human endothelial cells from oxidative stress: role of Ras-ERK1/2 signaling.

1 reference

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7 January 2021

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Cellular survival: a play in three Akts

1 reference

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7 January 2021

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Activated human N-ras oncogene enhances x-irradiation repair of mammalian cells in vitro less effectively at low dose rate. Implications for increased therapeutic ratio of low dose rate irradiation

1 reference

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7 January 2021

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Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells

1 reference

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7 January 2021

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p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons

1 reference

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7 January 2021

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RAS-Mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines.

1 reference

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7 January 2021

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Some ras-transformed cells have increased radiosensitivity and decreased repair of sublethal radiation damage

1 reference

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7 January 2021

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A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation

1 reference

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7 January 2021

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

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7 January 2021

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Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

1 reference

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7 January 2021

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206982

7 January 2021

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Redox regulation of cell signalling

1 reference

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7 January 2021

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Radioresistance induced by oncogenic transformation

1 reference

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7 January 2021

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Increased radioresistance of EJras-transformed human osteosarcoma cells and its modulation by lovastatin, an inhibitor of p21ras isoprenylation

1 reference

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7 January 2021

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Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

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7 January 2021

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Cytochrome c release is upstream to activation of caspase-9, caspase-8, and caspase-3 in the enhanced apoptosis of anaplastic thyroid cancer cells induced by manumycin and paclitaxel

1 reference

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7 January 2021

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Superoxides relay Ras protein's oncogenic message

1 reference

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7 January 2021

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Activation of the RacGTPase inhibits apoptosis in human tumor cells

1 reference

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7 January 2021

based on heuristic

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Transforming G proteins

1 reference

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The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1 reference

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7 January 2021

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Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals.

1 reference

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based on heuristic

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The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation

1 reference

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7 January 2021

based on heuristic

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Role of c-Jun N-terminal kinase/p38 stress signaling in 1-beta-D-arabinofuranosylcytosine-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206982

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206982

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

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7 January 2021

based on heuristic

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Differential involvement of p38 MAP kinase pathway and Bax translocation in the mitochondria-mediated cell death in TCR- and dexamethasone-stimulated thymocytes.

1 reference

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7 January 2021

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Identifiers

10.1038/SJ.ONC.1206982

1 reference

Europe PubMed Central

21 September 2017

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1 reference

Europe PubMed Central

21 September 2017

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