(Q40603116)

English

The mtfA transcription factor gene controls morphogenesis, gliotoxin production, and virulence in the opportunistic human pathogen Aspergillus fumigatus

scientific article published on 11 April 2014

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

The mtfA transcription factor gene controls morphogenesis, gliotoxin production, and virulence in the opportunistic human pathogen Aspergillus fumigatus (English)

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Aspergillus fumigatus

0 references

Transcription factor involved in regulation of morphogenesis, gliotoxin production and virulence

1 reference

6 February 2019

1 reference

based on heuristic

inferred from title

author name string

Timothy D Smith

1

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Ana M Calvo

2

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

11 April 2014

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Eukaryotic Cell

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

13

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

766-775

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

The putative C2H2 transcription factor MtfA is a novel regulator of secondary metabolism and morphogenesis in Aspergillus nidulans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

VeA regulates conidiation, gliotoxin production, and protease activity in the opportunistic human pathogen Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Dectin-1 is inducible and plays a crucial role in Aspergillus-induced innate immune responses in human bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Biosynthesis and function of gliotoxin in Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Coordination of secondary metabolism and development in fungi: the velvet family of regulatory proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Allergic bronchopulmonary aspergillosis in asthma and cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Pulmonary aspergillosis: clinical presentation, diagnostic tests, management and complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Conidiation color mutants of Aspergillus fumigatus are highly pathogenic to the heterologous insect host Galleria mellonella

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

The VeA regulatory system and its role in morphological and chemical development in fungi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Galleria mellonella and the study of fungal pathogenesis: making the case for another genetically tractable model host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Aspergillus fumigatus: principles of pathogenesis and host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP deletion attenuates virulence in mice immunosuppressed with hydrocortisone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Electromicroscopic observations on gliotoxin-induced apoptosis of cancer cells in culture and human cancer xenografts in transplanted SCID mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

GliZ, a transcriptional regulator of gliotoxin biosynthesis, contributes to Aspergillus fumigatus virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Aspergillus fumigatus: saprophyte or pathogen?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Fungal metabolite gliotoxin inhibits assembly of the human respiratory burst NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Invasive aspergillosis in patients with hematologic malignancies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

The expression of sterigmatocystin and penicillin genes in Aspergillus nidulans is controlled by veA, a gene required for sexual development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Relationship between secondary metabolism and fungal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Pathogenesis and clinical presentation of aspergillosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

The genus Aspergillus with special regard to the Aspergillus fumigatus group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Aspergillus fumigatus and aspergillosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Evidence for possible involvement of an elastolytic serine protease in aspergillosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Purification and characterization of factors produced by Aspergillus fumigatus which affect human ciliated respiratory epithelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Immunosuppression in vitro by a metabolite of a human pathogenic fungus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Invertebrate immunity--a primer for the non-specialist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Aspergillus nidulans wetA activates spore-specific gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Meiotic and Mitotic Recombination in Aspergillus and Its Chromosomal Aberrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

22 September 2017

Gliotoxin induces apoptosis in cultured macrophages via production of reactive oxygen species and cytochrome c release without mitochondrial depolarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

25 September 2017

Methods for using Galleria mellonella as a model host to study fungal pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

17 June 2018

Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

17 June 2018

Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

17 June 2018

Virulence ofCandida albicansmutants toward larvalGalleria mellonella(Insecta, Lepidoptera, Galleridae)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

17 June 2018

Virulence of an aspergillopepsin-deficient mutant of Aspergillus fumigatus and evidence for another aspartic proteinase linked to the fungal cell wall.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

17 June 2018

brlA is necessary and sufficient to direct conidiophore development in Aspergillus nidulans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

17 June 2018

Characterization of the velvet regulators in Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Discovery of gliotoxin as a new small molecule targeting thioredoxin redox system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Invasive fungal infections in allogeneic and autologous stem cell transplant recipients: a single-center study of 166 transplanted patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Tracing the endocytic pathway of Aspergillus nidulans with FM4-64.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Invasive pulmonary aspergillesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Complex control of the developmental regulatory locus brlA in Aspergillus nidulans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Infections caused by filamentous fungi in patients with hematologic malignancies. A report of 391 cases by GIMEMA Infection Program.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

20 August 2018

Gliotoxin from Aspergillus fumigatus affects phagocytosis and the organization of the actin cytoskeleton by distinct signalling pathways in human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054276

2 December 2018

The role of Aspergillus flavus veA in the production of extracellular proteins during growth on starch substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute toxicity of gliotoxin in hamsters

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of both granular cells and plasmatocytes in phagocytic reactions in the greater wax moth, Galleria mellonella

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gliotoxin induces apoptosis in mouse L929 fibroblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fungal gliotoxin targets the onset of superoxide-generating NADPH oxidase of human neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA fragmentation induced in macrophages by gliotoxin does not require protein synthesis and is preceded by raised inositol triphosphate levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gliotoxin causes oxidative damage to plasmid and cellular DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspergillus nidulans VeA subcellular localization is dependent on the importin alpha carrier and on light

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Invasive aspergillosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fungal metabolite gliotoxin: immunosuppressive activity on CTL-mediated cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion PCR and gene targeting in Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural occurrence of gliotoxin in turkeys infected with Aspergillus fumigatus, Fresenius

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIG-B: a homemade monophasic cocktail for the extraction of RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/24728192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/EC.00075-14

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40603116&oldid=1903548691"