(Q40604183)

22 September 2017

title

Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS. (English)

1 reference

Herpes simplex virus type 1

22 September 2017

1 reference

1 reference

John A Olschowka

1

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22 September 2017

William J Bowers

2

1 reference

22 September 2017

Sean D Hurley

3

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22 September 2017

Michael A Mastrangelo

4

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22 September 2017

Howard J Federoff

5

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22 September 2017

publication date

1 February 2003

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22 September 2017

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22 September 2017

volume

7

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22 September 2017

issue

2

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22 September 2017

page(s)

218-227

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Critical issues in gene therapy for neurologic disease

22 September 2017

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A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons

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Expression of nerve growth factor in vivo from a defective herpes simplex virus 1 vector prevents effects of axotomy on sympathetic ganglia

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Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome

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Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers

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7 January 2021

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7 January 2021

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TNFalpha and IFNgamma induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression

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7 January 2021

Humoral response to herpes simplex virus is complement-dependent

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Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

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7 January 2021

Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand

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7 January 2021

Cytokines and the nervous system II: Actions and mechanisms of action

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7 January 2021

Interleukin-1 beta induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures

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7 January 2021

Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy.

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7 January 2021

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7 January 2021

Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors

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7 January 2021

A prominent serine-rich region in Vmw175, the major transcriptional regulator protein of herpes simplex virus type 1, is not essential for virus growth in tissue culture

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7 January 2021

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7 January 2021

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7 January 2021

Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

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7 January 2021

Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors

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7 January 2021

Expression of human immunodeficiency virus type 1 gp120 from herpes simplex virus type 1-derived amplicons results in potent, specific, and durable cellular and humoral immune responses

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7 January 2021

The complement response against an oncolytic virus is species-specific in its activation pathways

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7 January 2021

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

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7 January 2021

Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response

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7 January 2021

Cytotoxicity of a replication-defective mutant of herpes simplex virus type 1

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7 January 2021

Transfer of the nerve growth factor gene into cell lines and cultured neurons using a defective herpes simplex virus vector. Transfer of the NGF gene into cells by a HSV-1 vector

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7 January 2021

Discordance between expression and genome transfer titering of HSV amplicon vectors: recommendation for standardized enumeration

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https://api.crossref.org/works/10.1016%2FS1525-0016%2802%2900036-9

7 January 2021

10.1016/S1525-0016(02)00036-9

Identifiers

DOI

1 reference

22 September 2017

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