(Q40606259)

22 September 2017

Tumor-specific adenoviral gene therapy: transcriptional repression of gene expression by utilizing p53-signal transduction pathways (English)

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22 September 2017

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2

Lars Zender

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author name string

Florian Kühnel

1

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22 September 2017

Lars Zender

2

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22 September 2017

Thomas Wirth

3

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22 September 2017

Bernd Schulte

4

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22 September 2017

Christian Trautwein

5

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22 September 2017

Michael Manns

6

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22 September 2017

Stefan Kubicka

7

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22 September 2017

1 January 2004

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22 September 2017

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22 September 2017

11

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22 September 2017

28-40

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22 September 2017

1

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https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700632

22 September 2017

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cites work

Analysis of the human carcinoembryonic antigen promoter core region in colorectal carcinoma-selective cytosine deaminase gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Use of transcriptional regulatory sequences of telomerase (hTER and hTERT) for selective killing of cancer cells

21 January 2018

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Prostate-specific expression of Bax delivered by an adenoviral vector induces apoptosis in LNCaP prostate cancer cells

21 January 2018

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Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

The IARC TP53 database: new online mutation analysis and recommendations to users

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Functional inactivation but not structural mutation of p53 causes liver cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Adenovirus E1A proteins inhibit activation of transcription by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Zik1, a transcriptional repressor that interacts with the heterogeneous nuclear ribonucleoprotein particle K protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

The Evi-1 proto-oncogene encodes a transcriptional repressor activity associated with transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Multiple mechanisms of transcriptional repression by YY1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Cloning and characterization of a novel zinc finger transcriptional repressor. A direct role of the zinc finger motif in repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

The interplay of DNA-binding proteins on the promoter of the mouse albumin gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Multiple sequence-specific transcription factors modulate cytomegalovirus enhancer activity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

DNA recognition by GAL4: structure of a protein-DNA complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

DNA sequence preferences of GAL4 and PPR1: how a subset of Zn2 Cys6 binuclear cluster proteins recognizes DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Krüppel-associated box-mediated repression of RNA polymerase II promoters is influenced by the arrangement of basal promoter elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Assessing TP53 status in human tumours to evaluate clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

p53 mutation pattern and expression of c-erbB2 and c-met in gastric cancer: relation to histological subtypes, Helicobacter pylori infection, and prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

p53 represses CAAT enhancer-binding protein (C/EBP)-dependent transcription of the albumin gene. A molecular mechanism involved in viral liver infection with implications for hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Ectodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

p53-dependent cell death/apoptosis is required for a productive adenovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Tumour-specific therapeutic adenovirus vectors: repression of transgene expression in healthy cells by endogenous p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Krüppel-associated boxes are potent transcriptional repression domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

Transcriptional repression from the c-myc P2 promoter by the zinc finger protein ZF87/MAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

inferred from DOI database lookup

7 January 2021

based on heuristic

p53 status and the efficacy of cancer therapy in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

inferred from DOI database lookup

7 January 2021

based on heuristic

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700632

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CGT.7700632

1 reference

Dimensions Publication ID

22 September 2017

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1 reference