(Q40606374)

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Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms.

scientific article published on 17 December 2003

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16 November 2019

Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms (English)

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16 November 2019

Silvia Martin-Puig

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16 November 2019

Julian Aragones Lopez

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16 November 2019

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David R Jones

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16 November 2019

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Elisa Temes

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16 November 2019

Gemma Olmos

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16 November 2019

Manuel O Landázuri

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16 November 2019

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17 December 2003

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16 November 2019

Journal of Biological Chemistry

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16 November 2019

279

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16 November 2019

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16 November 2019

9504-9511

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16 November 2019

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

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21 January 2018

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

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HIF hydroxylation and the mammalian oxygen-sensing pathway

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21 January 2018

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HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels

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21 January 2018

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

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21 January 2018

Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts

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21 January 2018

Phospholipase D activity is required for actin stress fiber formation in fibroblasts

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21 January 2018

The role of phosphatidic acid in the regulation of the Ras/MEK/Erk signaling cascade

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21 January 2018

Functional analysis of a phosphatidic acid binding domain in human Raf-1 kinase: mutations in the phosphatidate binding domain lead to tail and trunk abnormalities in developing zebrafish embryos

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21 January 2018

Phosphatidic acid is a potent and selective inhibitor of protein phosphatase 1 and an inhibitor of ceramide-mediated responses

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21 January 2018

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

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21 January 2018

Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes

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21 January 2018

Tumour suppression by the human von Hippel-Lindau gene product

1 reference

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21 January 2018

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

1 reference

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21 January 2018

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

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21 January 2018

The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen

1 reference

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The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

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Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

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Activation of the hypoxia‐inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors

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K+ and Ca2+ channel activity and cytosolic [Ca2+] in oxygen-sensing tissues

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Identifiers

10.1074/JBC.M310658200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14681229%20AND%20SRC:MED&resulttype=core&format=json

16 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14681229%20AND%20SRC:MED&resulttype=core&format=json

16 November 2019

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