(Q40607421)

22 September 2017

title

Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease (English)

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22 September 2017

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7

William M Mauck

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22 September 2017

9

M Flint Beal

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22 September 2017

David K Simon

1

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22 September 2017

Michael T Lin

2

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22 September 2017

Leiya Zheng

3

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22 September 2017

Guang-Jun Liu

4

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22 September 2017

Colette H Ahn

5

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22 September 2017

Lauren M Kim

6

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22 September 2017

Florence Twu

8

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22 September 2017

Donald R Johns

10

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22 September 2017

publication date

1 January 2004

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22 September 2017

published in

Neurobiology of Aging

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22 September 2017

volume

25

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22 September 2017

issue

1

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22 September 2017

page(s)

71-81

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Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Oxidants, antioxidants, and the degenerative diseases of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Sequence and organization of the human mitochondrial genome

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Endogenous oxidative damage of mtDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Age-dependent impairment of mitochondrial function in primate brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Point mutations of the mtDNA control region in normal and neurodegenerative human brains

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Modelling the effects of age-related mtDNA mutation accumulation; Complex I deficiency, superoxide and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

In vivo regulation of oxidative phosphorylation in cells harboring a stop-codon mutation in mitochondrial DNA-encoded cytochrome c oxidase subunit I.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Evidence that two reports of mtDNA cytochrome c oxidase "mutations" in Alzheimer's disease are based on nDNA pseudogenes of recent evolutionary origin

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Very rare complementation between mitochondria carrying different mitochondrial DNA mutations points to intrinsic genetic autonomy of the organelles in cultured human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Does oxidative damage to DNA increase with age?

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial mutational spectra in human cells and tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Preservation of midbrain catecholaminergic neurons in very old human subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

The etiology of Parkinson's disease with emphasis on the MPTP story

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Quantitative allele-specific PCR: demonstration of age-associated accumulation in human tissues of the A-->G mutation at nucleotide 3243 in mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Unbiased morphometrical measurements show loss of pigmented nigral neurones with ageing.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Analysis of phylogenetically reconstructed mutational spectra in human mitochondrial DNA control region

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial DNA: molecular fossils in the nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Somatic mutations of the mitochondrial genome in human colorectal tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Bioenergetic consequences of accumulating the common 4977-bp mitochondrial DNA deletion

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Threshold effect and tissue specificity. Implication for mitochondrial cytopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Low mutational burden of individual acquired mitochondrial DNA mutations in brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Accumulation of deletions in human mitochondrial DNA during normal aging: analysis by quantitative PCR

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Hypervariable sites in the mtDNA control region are mutational hotspots

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Origin and functional consequences of the complex I defect in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mutational scanning of mitochondrial DNA by two-dimensional electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Muscle fibres: applications for the study of the metabolic consequences of enzyme deficiencies in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2803%2900037-X

7 January 2021

10.1016/S0197-4580(03)00037-X

Identifiers

DOI

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release_qesl2ylkojempbfb2t5e3nfhxy

22 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/qesl2ylkojempbfb2t5e3nfhxy

24 November 2022

mapped directly with Wikidata item

1 reference