(Q40618222)

22 September 2017

title

Development of a DNA Vaccine Designed to Induce Cytotoxic T Lymphocyte Responses to Multiple Conserved Epitopes in HIV-1 (English)

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

30 March 2024

0 references

0 references

1 reference

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

30 March 2024

8

Alessandro Sette

1 reference

22 September 2017

2

Denise McKinney

1 reference

22 September 2017

6

Claire Crimi

1 reference

22 September 2017

4

Samantha MaWhinney

1 reference

22 September 2017

Michelle Anders

3

1 reference

22 September 2017

Jeri Forster

5

1 reference

22 September 2017

Scott Southwood

7

1 reference

22 September 2017

Robert Chesnut

9

1 reference

22 September 2017

Cara C. Wilson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607970

30 March 2024

Denise McKinney

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607970

30 March 2024

Samantha MaWhinney

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607970

30 March 2024

Mark J. Newman

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607970

30 March 2024

Brian D. Livingston

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14607970

30 March 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

22 September 2017

15 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14607970

full work available at URL

30 March 2024

published in

Journal of Immunology

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22 September 2017

volume

171

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22 September 2017

issue

10

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22 September 2017

page(s)

5611-5623

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Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

22 September 2017

cites work

1

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection

30 March 2024

3

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Studies in subjects with long-term nonprogressive human immunodeficiency virus infection

30 March 2024

4

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Virus burden in long-term survivors of human immunodeficiency virus (HIV) infection is a determinant of anti-HIV CD8+ lymphocyte activity

30 March 2024

6

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Recognition of the highly conserved YMDD region in the human immunodeficiency virus type 1 reverse transcriptase by HLA-A2-restricted cytotoxic T lymphocytes from an asymptomatic long-term nonprogressor

30 March 2024

7

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

30 March 2024

8

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

30 March 2024

9

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors

30 March 2024

10

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Correlation between breadth of memory HIV-specific cytotoxic T cells, viral load and disease progression in HIV infection.

30 March 2024

11

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

30 March 2024

12

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

30 March 2024

13

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination

30 March 2024

14

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression f

30 March 2024

17

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

30 March 2024

18

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

30 March 2024

19

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence?

30 March 2024

20

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Emergence of Cytotoxic T Lymphocyte Escape Mutants following Antiretroviral Treatment Suspension in Rhesus Macaques Infected with SIVmac251

30 March 2024

21

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism

30 March 2024

23

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients

30 March 2024

24

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Safety and immunogenicity of an HLA-based HIV envelope polyvalent synthetic peptide immunogen. DATRI 010 Study Group. Division of AIDS Treatment Research Initiative

30 March 2024

25

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Multiepitopic B- and T-cell responses induced in humans by a human immunodeficiency virus type 1 lipopeptide vaccine

30 March 2024

26

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Vaccination to prevent persistent viral infection.

30 March 2024

28

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Protection by minigenes: a novel approach of DNA vaccines

30 March 2024

29

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Vaccination and protection from a lethal viral infection: identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope

30 March 2024

31

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Quantitative and qualitative analyses of the immune responses induced by a multivalent minigene DNA vaccine

30 March 2024

32

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime

30 March 2024

34

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya

30 March 2024

35

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Induction of CD8+ T cells using heterologous prime-boost immunisation strategies

30 March 2024

36

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Design of a polyepitope construct for the induction of HLA-A0201-restricted HIV 1-specific CTL responses using HLA-A*0201 transgenic, H-2 class I KO mice

30 March 2024

37

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

A prime-boost immunisation regimen using DNA followed by recombinant modified vaccinia virus Ankara induces strong cellular immune responses against the Plasmodium falciparum TRAP antigen in chimpanzees

30 March 2024

38

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Development of a DNA-MVA/HIVA vaccine for Kenya

30 March 2024

39

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

HLA supertypes and supermotifs: a functional perspective on HLA polymorphism

30 March 2024

40

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

30 March 2024

41

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays

30 March 2024

44

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations

30 March 2024

46

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules

30 March 2024

48

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex

30 March 2024

50

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Derivation of HLA-B*0702 transgenic mice: functional CTL repertoire and recognition of human B*0702-restricted CTL epitopes

30 March 2024

51

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation

30 March 2024

52

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif

30 March 2024

53

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines

30 March 2024

54

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Protective interactive noncondensing (PINC) polymers for enhanced plasmid distribution and expression in rat skeletal muscle

30 March 2024

56

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Expression of biologically active human insulin-like growth factor-I following intramuscular injection of a formulated plasmid in rats

30 March 2024

57

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Characterization of an in situ IFN-gamma ELISA assay which is able to detect specific peptide responses from freshly isolated splenocytes induced by DNA minigene immunization

30 March 2024

58

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy

30 March 2024

59

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Immune control of HIV: the obstacles of HLA and viral diversity

30 March 2024

60

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Evolutionary and immunological implications of contemporary HIV-1 variation.

30 March 2024

61

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Diversity considerations in HIV-1 vaccine selection

30 March 2024

62

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design?

30 March 2024

63

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Human papillomavirus (HPV) infection in Southern Africa: prevalence, immunity, and vaccine prospects

30 March 2024

64

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Conserved domains of subtype C nef from South African HIV type 1-infected individuals include cytotoxic T lymphocyte epitope-rich regions

30 March 2024

65

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.

30 March 2024

66

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

30 March 2024

67

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

30 March 2024

68

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Escape of human immunodeficiency virus from immune control

30 March 2024

69

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

30 March 2024

70

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Mother-to-child transmission of HIV infection and CTL escape through HLA-A2-SLYNTVATL epitope sequence variation

30 March 2024

71

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation

30 March 2024

72

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity

30 March 2024

73

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Recognition of a small number of diverse epitopes dominates the cytotoxic T lymphocytes response to HIV type 1 in an infected individual

30 March 2024

76

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Monitoring HIV-specific CD8+ T cell responses by intracellular cytokine production

30 March 2024

77

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

30 March 2024

78

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection

30 March 2024

79

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles

30 March 2024

80

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Majority of peptides binding HLA-A*0201 with high affinity crossreact with other A2-supertype molecules

30 March 2024

82

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Long-term non-progression in HIV infection: clinico pathological issues

30 March 2024

83

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

The role of CD4(+) T helper cells in the cytotoxic T lymphocyte response to HIV-1.

30 March 2024

84

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Immunodominance in virus-induced CD8(+) T-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon

30 March 2024

85

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Competition Between CTL Narrows the Immune Response Induced by Prime-Boost Vaccination Protocols

30 March 2024

86

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

30 March 2024

87

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Enhancement of cellular immune response in HIV-1 seropositive individuals: A DNA-based trial

30 March 2024

88

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response

30 March 2024

89

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans

30 March 2024

90

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Vaccination of seronegative volunteers with a human immunodeficiency virus type 1 env/rev DNA vaccine induces antigen-specific proliferation and lymphocyte production of beta-chemokines

30 March 2024

91

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

Cellular HIV-1 immune responses in natural infection and after genetic immunization.

30 March 2024

92

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

T-cell responses induced in normal volunteers immunized with a DNA-based vaccine containing HIV-1 env and rev

30 March 2024

93

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.10.5611

30 March 2024

Identifiers

1 reference

22 September 2017

1 reference