(Q40619935)

22 September 2017

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title

Clinical pharmacokinetics of slow-acting antirheumatic drugs (English)

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22 September 2017

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S E Tett

1

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22 September 2017

1 November 1993

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Clinical Pharmacokinetics

22 September 2017

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22 September 2017

25

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22 September 2017

5

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22 September 2017

392-407

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https://scigraph.springernature.com/pub.10.2165/00003088-199325050-00005

22 September 2017

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12 December 2020

Dose, plasma concentration and response relationships of D-penicillamine in patients with rheumatoid arthritis

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Sulphasalazine in the treatment of rheumatoid arthritis: relationship of dose and serum levels to efficacy

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12 December 2020

The single dose kinetics of chloroquine and its major metabolite desethylchloroquine in healthy subjects

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12 December 2020

Distribution of gold in blood following administration of auranofin (SK&F D-39162)

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12 December 2020

A dose-ranging study of the pharmacokinetics of hydroxy-chloroquine following intravenous administration to healthy volunteers

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Chloroquine and desethylchloroquine in plasma, serum, and whole blood: problems in assay and handling of samples

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Protein binding of chloroquine enantiomers and desethylchloroquine

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Chloroquine excretion following malaria prophylaxis

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12 December 2020

Analytical and semi-preparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers

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12 December 2020

The effect of cyanide on the uptake of gold by red blood cells

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12 December 2020

Penicillamine nephropathy and iron

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12 December 2020

Dosage of Antimalarial Drugs for Children with Juvenile Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Clinical Study with Determination of Serum Concentrations of Chloroquine and Hydroxychloroquine

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Bioavailability of hydroxychloroquine tablets assessed with deconvolution techniques

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12 December 2020

Clinical pharmacokinetics of D-penicillamine

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12 December 2020

The metabolism and pharmacology of D-penicillamine in man.

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12 December 2020

Reduction in oral penicillamine absorption by food, antacid, and ferrous sulfate.

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12 December 2020

Pharmacokinetic interactions of penicillamine in rheumatoid arthritis

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12 December 2020

In vitro activity of chloroquine, the two enantiomers of chloroquine, desethylchloroquine and pyronaridine against Plasmodium falciparum.

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12 December 2020

D-penicillamine and D-penicillamine-protein disulphide in plasma and synovial fluid of patients with rheumatoid arthritis

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12 December 2020

High-performance liquid chromatographic separation of the enantiomers of hydroxychloroquine and its major metabolites in biological fluids using an α1-acid glycoprotein stationary phase

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12 December 2020

Concentration-effect relationship of hydroxychloroquine in rheumatoid arthritis--a cross sectional study.

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12 December 2020

Radiological progression in rheumatoid arthritis: do D-penicillamine and hydroxychloroquine have different effects?

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12 December 2020

Bioavailability of hydroxychloroquine tablets in healthy volunteers

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12 December 2020

Life table analysis of 879 treatment episodes with slow acting antirheumatic drugs in community rheumatology practice

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12 December 2020

On the question of dose-dependent chloroquine elimination of a single oral dose

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12 December 2020

Disposition of the enantiomers of hydroxychloroquine in patients with rheumatoid arthritis following multiple doses of the racemate

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12 December 2020

The metabolism of 35S-D-penicillamine in man

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12 December 2020

Pharmacokinetics of auranofin a single dose study in man.

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12 December 2020

The potential role of lysosomes in tissue distribution of weak bases

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12 December 2020

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12 December 2020

Auranofin. New oral gold compound for treatment of rheumatoid arthritis

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12 December 2020

Comparison of the single dose pharmacokinetics of sulphasalazine in rheumatoid arthritis and inflammatory bowel disease

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The treatment of rheumatic polyarthritis with acid azo compounds

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12 December 2020

Penicillamine kinetics in normal subjects.

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12 December 2020

Plasma hydroxychloroquine concentrations and efficacy in rheumatoid arthritis

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12 December 2020

Enantioselective analysis of chloroquine and desethylchloroquine after oral administration of racemic chloroquine

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12 December 2020

Characterization of chloroquine plasma protein binding in man.

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12 December 2020

Apparent dose-dependence of chloroquine pharmacokinetics due to limited assay sensitivity and short sampling times

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12 December 2020

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The pharmacokinetics of albumin conjugates of D-penicillamine in humans

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12 December 2020

Monitoring Gold Plasma Levels in Rheumatoid Arthritis

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12 December 2020

Distribution of gold among plasma fractions in rheumatoid patients undergoing chrysotherapy compared with its distribution in plasma incubated with aurothiomalate in vitro

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12 December 2020

The effect of the acetylator phenotype on the metabolism of sulphasalazine in man

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12 December 2020

Distribution of chloroquine and its metabolite desethyl-chloroquine in human blood cells and its implication for the quantitative determination of these compounds in serum and plasma

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12 December 2020

Single dose pharmacokinetics of auranofin in rheumatoid arthritis

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12 December 2020

Pharmacodynamics of197Au and195Au labeled aurothiomalate in blood. Correlation with course of rheumatoid arthritis, gold toxicity and gold excretion

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12 December 2020

A double-blind trial of high versus conventional dosages of gold salts for rheumatoid arthritis

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12 December 2020

Classification of antirheumatic drugs. A new proposal

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12 December 2020

Sulfasalazine in the rheumatic disease

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12 December 2020

Gold pharmacokinetics in breast milk and serum of a lactating woman

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12 December 2020

The disposition of chloroquine in healthy Nigerians after single intravenous and oral doses

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12 December 2020

Does Drug Therapy Slow Radiographic Deterioration in Rheumatoid Arthritis?

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12 December 2020

The disposition and metabolism of sulphasalazine (salicylazosulphapyridine) in man

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12 December 2020

Treatment complications of rheumatoid arthritis with gold, hydroxychloroquine, D-penicillamine, and levamisole

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12 December 2020

A comparison of conventional and low dose sodium aurothiomalate treatment in rheumatoid arthritis

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12 December 2020

Pharmacokinetics and azo-link cleavage of salazopyrine in man.

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12 December 2020

Gold kinetics following aurothiomalate therapy: use of a whole-body radiation counter.

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12 December 2020

Pharmacokinetics of chloroquine: saliva and plasma levels relationship

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12 December 2020

Steady state disposition of chloroquine in patients with rheumatoid disease

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12 December 2020

Chloroquine levels in blood during chronic treatment of patients with rheumatoid arthritis

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12 December 2020

Which component of sulphasalazine is active in rheumatoid arthritis?

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12 December 2020

A multicentre1) controlled trial of the effects of different dosage of gold therapy, followed by a maintenance dosage

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12 December 2020

Absorption and in vivo dissolution of hydroxycholoroquine in fed subjects assessed using deconvolution techniques.

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12 December 2020

Chloroquine serum concentration and side effects: Evidence for dose-dependent kinetics

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12 December 2020

Chloroquine kinetics in the undernourished

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12 December 2020

Blood samples and chloroquine assay

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12 December 2020

Bioavailability of single and multiple doses of enteric-coated mesalamine and sulphasalazine

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12 December 2020

Chloroquine enantiomers. Activity against P. vinckei and binding on DNA (author's transl)

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12 December 2020

The pharmacokinetics of D-penicillamine in man

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12 December 2020

D-penicillamine in patients with rheumatoid arthritis. Serum levels, pharmacokinetic aspects, and correlation with clinical course and side effects

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12 December 2020

Dose response studies and longterm evaluation of auranofin in rheumatoid arthritis

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12 December 2020

Hemodialysis clearance of chloroquine in uremic patients

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12 December 2020

Auranofin versus injectable gold. Comparison of pharmacokinetic properties

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12 December 2020

The influence of various types of breakfast on chloroquine levels

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12 December 2020

Tissue gold concentration in a rheumatoid arthritic receiving chrysotherapy

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12 December 2020

Effects of hydroxychloroquine and sulphasalazine on progression of joint damage in rheumatoid arthritis

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12 December 2020

Gold levels in serum during the treatment of rheumatoid arthritis with gold sodium thiomalate.

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12 December 2020

Comparative pharmacokinetics of parenteral and oral gold compounds

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12 December 2020

Disposition of chloroquine in man after single intravenous and oral doses

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12 December 2020

Studies of the metabolism of some compounds of the 4-amino-7-chloroquinoline series.

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12 December 2020

Plasma protein binding of the enantiomers of hydroxychloroquine and metabolites

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12 December 2020

Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography

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12 December 2020

Remodeling the pyramid--a concept whose time has come

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12 December 2020

The effect of smoking on the distribution of gold in blood

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12 December 2020

Auranofin: an oral chrysotherapeutic agent for the treatment of rheumatoid arthritis

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12 December 2020

Sulphasalazine in arthritis--an old drug rediscovered

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12 December 2020

Steady-State Pharmacokinetics of Hydroxychloroquine in Rheumatoid Arthritis Patients

1 reference

12 December 2020

The effect of age and acetylator phenotype on the pharmacokinetics of sulfasalazine in patients with rheumatoid arthritis

1 reference

12 December 2020

Penicillamine in rheumatoid arthritis. A problem of toxicity

1 reference

12 December 2020

High-performance liquid chromatographic assay for hydroxychloroquine and metabolites in blood and plasma, using a stationary phase of poly(styrene divinylbenzene) and a mobile phase at pH 11, with fluorimetric detection

1 reference

12 December 2020

Sulphasalazine in rheumatoid arthritis: a double blind comparison of sulphasalazine with placebo and sodium aurothiomalate

1 reference

12 December 2020

Gold metabolism in patients with rheumatoid arthritis treated with gold compounds—reinvestigated

1 reference

12 December 2020

Bioavailability of hydroxychloroquine tablets in patients with rheumatoid arthritis

1 reference

12 December 2020

Selective concentration and localization of gold in macrophages of synovial and other tissues during and after chrysotherapy in rheumatoid patients

1 reference

12 December 2020

Bioavailability and pharmacokinetics of D-penicillamine

1 reference

12 December 2020

Urinary metabolism of chloroquine

1 reference

12 December 2020

Hydroxychloroquine overdosage

1 reference

12 December 2020

Mechanism of action, pharmacology, clinical efficacy and side effects of auranofin. An orally administered organic gold compound for the treatment of rheumatoid arthritis

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12 December 2020

10.2165/00003088-199325050-00005

Identifiers

DOI

1 reference

PubMed ID

7904547

Dimensions Publication ID

22 September 2017

0 references

1 reference

PubMed ID

7904547