(Q40620583)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

review article

1 reference

title

Amidines and guanidines in medicinal chemistry (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

author name string

J V Greenhill

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

P Lue

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

publication date

1 January 1993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

Progress in medicinal chemistry

28 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

page(s)

203-326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7905649%20AND%20SRC:MED&resulttype=core&format=json

Comparison of cardiovascular responses to the bradycardic drugs, alinidine, AQ-A 39, and mixidine, in the anesthetized dog.

28 October 2019

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7 January 2021

Antispasmodics: Esters of Heterocyclic Alcohols

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7 January 2021

Antimuscarinic effects of (R)- and (S)- oxyphencyclimine hydrochloride

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7 January 2021

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7 January 2021

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7 January 2021

The discovery of bretylium and bethanidine

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7 January 2021

Meobentine sulphate (bis[N-4-methoxybenzyl-N′N″-dimethylguanidine]sulphate): a new antidysrhythmic agent

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7 January 2021

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7 January 2021

Potassium channel blockade: A mechanism for suppressing ventricular fibrillation

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7 January 2021

On the physiological disposition and possible mechanism of the antihypertensive action of debrisoquin

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7 January 2021

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Some New Adrenergic Neurone Blocking Agents

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7 January 2021

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Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion

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7 January 2021

Amidines. 2. A new class of antihypertensive agents. 1,2,3,5-Tetrahydroimidazo(2,1-b)quinazolines

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7 January 2021

Direct prediction of dissociation constants (pKa's) of clonidine-like imidazolines, 2-substituted imidazoles, and 1-methyl-2-substituted-imidazoles from 3D structures using a comparative molecular field analysis (CoMFA) approach

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Pinacidil Opens ATP-Dependent K+ Channels in Cardiac Myocytes in an ATP-and Temperature-Dependent Manner

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7 January 2021

Centrally acting sympatholytic agents in the treatment of congestive heart failure. A review of the literature

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7 January 2021

Delineation of three pharmacological subtypes of α2-adrenoceptor in the rat kidney

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7 January 2021

New horizons in the pharmacologic management of peptic ulceration

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7 January 2021

4-(Diphenylmethyl)-1-[(imino)methyl]piperidines as gastric antisecretory agents

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7 January 2021

Inhibition of food stimulated acid secretion by fenoctimine, a new anti-secretory agent

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7 January 2021

6 Ranitidine and Other H2-Receptor Antagonists: Recent Developments

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Ranitidine. An updated review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in peptic ulcer disease and other allied diseases

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7 January 2021

Negative chronotropic effects of nizatidine

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7 January 2021

(Imidazolylphenyl)formamidines. A structurally novel class of potent histamine H2 receptor antagonists

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7 January 2021

Positive inotropic action of saponins on isolated atrial and papillary muscles from the guinea-pig

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7 January 2021

Action of mifentidine on the secretory response to sham feeding and pentagastrin and on serum gastrin in duodenal ulcer patients

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7 January 2021

Comparative study of mifentidine and ranitidine in the short-term treatment of duodenal ulcer

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7 January 2021

Effect of mifentidine on peptone meal-stimulated gastric acid secretion and plasma gastrin levels in duodenal ulcer patients.

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7 January 2021

Medicinal chemical studies on synthetic protease inhibitors, trans-4-guanidinomethylcyclohexanecarboxylic acid aryl esters

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7 January 2021

[Effects of 2-benzyloxycarbonylphenyl trans-4-guanidinomethylcyclohexanecarboxylate hydrochloride monohydrate (TKG01) and its clathrate compound with beta-cyclodextrin (TA903) on experimental gastric ulcers and gastric secretion in rats]

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7 January 2021

Cyanoguanidine-thiourea equivalence in the development of the histamine H2-receptor antagonist, cimetidine

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7 January 2021

The natural history of peptic ulcer disease: the influence of H2-antagonist treatment

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7 January 2021

ICI 125,211: A new gastric antisecretory agent acting on histamine H2-receptors

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Specific binding of 3H-tiotidine to histamine H2 receptors in guinea pig cerebral cortex.

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Identification and characterization of histamine H1- and H2-receptors in guinea-pig left atrial membranes by [3H]-mepyramine and [3H]-tiotidine binding

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7 January 2021

Anti-secretory activity of the novel H2-antagonist, HUK 978, in rat, guinea-pig and dog.

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7 January 2021

The histamine H2 receptor agonist impromidine: synthesis and structure-activity considerations

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7 January 2021

Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors

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7 January 2021

Impromidine, a potent inhibitor of histamine methyltransferase (HMT) and diamine oxidase (DAO)

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7 January 2021

[Structure-activity relationships of histamine analogues, XX: absolute configuration and histamine-like activity of the enantiomeric alpha-methylhistamines]

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7 January 2021

Structure-activity relationships of histamine analogues, XXIII: absolute configuration and histamine-like activity of the enantiomeric alpha-chloromethylhistamines and N alpha-methyl-alpha-chloromethylhistamines (author's transl)

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7 January 2021

Synthesis and in vitro pharmacology of arpromidine and related phenyl(pyridylalkyl)guanidines, a potential new class of positive inotropic drugs

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7 January 2021

Bioisosteric prototype design of biaryl imidazolyl and triazolyl competitive histamine H2-receptor antagonists

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7 January 2021

An improved preparation and use of 2-bromoacetoacetaldehyde in a new synthesis of 2-substituted-4-acetylimidazoles

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7 January 2021

The antisecretory effects of zaltidine, a novel long-acting H2-receptor antagonist, in healthy volunteers and in subjects with a past history of duodenal ulcer

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7 January 2021

A double-blind crossover comparison of lidamidine, loperamide and placebo for the control of chronic diarrhoea

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7 January 2021

Antihistamine activity and central effects of WAL 801 CL in man.

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7 January 2021

Synthesis and structure-activity study of protease inhibitors. IV. Amidinonaphthols and related acyl derivatives

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7 January 2021

New synthetic inhibitors of C1r̄, C1 esterase, thrombin, plasmin, kallikrein and trypsin

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7 January 2021

Pharmacological studies of FUT-175, nafamstat mesilate. I. Inhibition of protease activity in in vitro and in vivo experiments.

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7 January 2021

Pharmacological studies of FUT-175, nafamostat mesilate. V. Effects on the pancreatic enzymes and experimental acute pancreatitis in rats

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7 January 2021

The effect of FUT-175 (Nafamstat Mesilate) on C3a, C4a and C5a generation in vitro and inflammatory reactions in vivo

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7 January 2021

Improvement in wound healing by epidermal growth factor (EGF) ointment. I. Effect of nafamostat, gabexate, or gelatin on stabilization and efficacy of EGF

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7 January 2021

Enhanced bioavailability of subcutaneously injected insulin by pretreatment with ointment containing protease inhibitors

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7 January 2021

Basic antiinflammatory compounds. N,N',N''-Trisubstituted guanidines

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7 January 2021

Cyclic guanidines. X. Synthesis of 2-(2,2-disubstituted ethenyl- and ethyl)-2-imidazolines as potent hypoglycemics

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7 January 2021

The selectivity of DG-5128 as an α2-adrenoceptor antagonist

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7 January 2021

Sulfonyliminoimidazolidines. A new class of oral hypoglycemic agents. 1. 1-[[p-[2-(acylamino)ethyl]phenyl]sulfonyl]-2-iminoimidazolidines

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7 January 2021

Sulfonyliminoimidazolidines. A new class of oral hypoglycemia agents. 2. Mode of action and x-ray structure of 1-[[p-[2-(crotonylamine)ethyl]phenyl]sulfonyl]-3-cyclohexyl-2-iminoimidazolidine

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7 January 2021

Linogliride fumarate, representing a new class of oral hypoglycemic agent for diabetes.

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7 January 2021

Hypoglycemic Agents. III.1—3N1-Alkyl- and Aralkylbiguanides

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7 January 2021

CCXIV.?The preparation of methylguanidine, and of ??-dimethylguanidine by the interaction of dicyanodiamide, and methylammonium and dimethylammonium chlorides respectively

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7 January 2021

Hypoglycemic Agents. I. 1 Chemical Properties of β-Phenethylbiguanide. 2 A New Hypoglycemic Agent 3

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7 January 2021

Resorption and biological degradation of N1-beta-phenethyl-biguanide (phenformin)

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7 January 2021

Lactic acidosis in biguanide-treated diabetics: a review of 330 cases

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7 January 2021

Studies on the antimicrobial action of terephthalanilide and related drugs

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7 January 2021

Pentamidine isethionate. A review of its antiprotozoal activity, pharmacokinetic properties and therapeutic use in Pneumocystis carinii pneumonia

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7 January 2021

Inhaled pentamidine. An overview of its pharmacological properties and a review of its therapeutic use in Pneumocystis carinii pneumonia

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7 January 2021

Pentamidine: a review

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7 January 2021

Structure and DNA binding activity of analogs of 1,5-bis(4-amidinophenoxy)pentane (pentamidine)

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7 January 2021

3 : 3′-Diamidinocarbanilide: a New Drug Active against Babesial Infections

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7 January 2021

Activity of pentamidine and pentamidine analogs against Toxoplasma gondii in cell cultures

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7 January 2021

Antistaphylococcal activity of pentamidine

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7 January 2021

Effects of pentamidine alone and in combination with ketoconazole or itraconazole on the growth of Candida albicans

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7 January 2021

Structure of cytosinine, a structural component of blasticidin S

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7 January 2021

The structure of blasticidin S

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7 January 2021

Nucleosides XXXII. On the structure of blasticidin S, a nucleoside antibiotic

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7 January 2021

Crystal and molecular structure of the antiobiotic blasticidin S hydrochloride pentahydrate

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7 January 2021

Biosynthesis of blasticidin S from cytosylglucuronic acid (CGA). Isolation of cytosine/UDPglucuronosyltransferase and incorporation of CGA by Streptomyces griseochromogenes

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7 January 2021

[IR- and nuclear resonance spectrometric studies on the structure of sulfanilylguanidine]

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7 January 2021

Nitrogen-15 nuclear magnetic resonance. Structure of sulfaguanidine1

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7 January 2021

Total synthesis of streptomycin

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7 January 2021

STREPTOMYCES ANTIBIOTICS. IX. DIHYDROSTREPTOMYCIN

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7 January 2021

Studies on antibiotics. XVI. Isolation and identification of dihydrostreptomycin produced by a new streptomyces, Streptomyces humidus nov. sp

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7 January 2021

Total synthesis of dihydrostreptomycin.

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7 January 2021

On the mechanism of translocation of dihydrostreptomycin across the bacterial cytoplasmic membrane.

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7 January 2021

A study of the structure of bluensomycin with the tetramminecopper reagent

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7 January 2021

Total structure of capreomycin IB, a tuberculostatic peptide antibiotic

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7 January 2021

The chemical structure of capreomycin

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7 January 2021

The revised structure of capreomycin

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7 January 2021

In vitro and in vivo laboratory studies on the antituberculous activity of capreomycin

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7 January 2021

850. Bisdiguanides having antibacterial activity

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7 January 2021

In vitro antiplaque properties of a series of alkyl bis(biguanides)

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7 January 2021

The synthesis of some heterocyclic derivatives of biguanide with antibacterial activity

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7 January 2021

The effect of diminazene aceturate and isometamidium chloride on cultured procyclic forms of susceptible and drug-resistant Trypanosoma congolense

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7 January 2021

Expression of resistance to isometamidium and diminazene in Trypanosoma congolense in Boran cattle infected by Glossina morsitans centralis

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7 January 2021

Metamidium: a new trypanocidal drug

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7 January 2021

Structure of Isometamidium (M. and B. 4180A), 7-m-Amidinophenyldiazoamino-2-amino-10-ethyl-9-phenylphenanthridinium Chloride Hydrochloride, the Red Isomer present in Metamidium

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7 January 2021

The pharmacology of isometamidium

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7 January 2021

The effect of imidocarb dipropionate on Babesia ovis infection in sheep

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7 January 2021

A comparison of the efficacy of imidocarb dipropionate and tetracycline hydrochloride in the treatment of canine ehrlichiosis

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7 January 2021

The use of amitraz (N1-(2,4-dimethylphenyl)-N-[(2,4-dimethylphenyl)imino)-methyl]-N-methylmethanimidamide) in demodecosis in dogs

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7 January 2021

A metabolite of paludrine with high antimalarial activity

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7 January 2021

1,3-Bis(p-chlorobenzylideneamino)guanidine hydrochloride (robenzidene): new poultry anticoccidial agent

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7 January 2021

Observations on a Drug Resistant Strain of Eimeria tenella

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7 January 2021

Novel anthelmintic agents. II. Pyrantel and other cyclic amidines

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7 January 2021

Novel anthelmintic agents. 6. Pyrantel analogs with activity against whipworm

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7 January 2021

Anthelmintic Studies with Pyrantel. I. Therapeutic and Prophylactic Efficacy against the Enteral Stages of Various Helminths in Mice and Dogs

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7 January 2021

Efficacy of a tablet containing pyrantel embonate, febantel and praziquantel against T canis in dogs

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7 January 2021

Controlled laboratory trials in sheep with the anthelmintic pyrantel tartrate

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7 January 2021

Some pharmacodynamic effects of the nematocides: methyridine, tetramisole and pyrantel

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7 January 2021

Toxocara vitulorum: treatment based on the duration of the infectivity of buffalo cows (Bubalus bubalis) for their calves

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7 January 2021

The anthelmintic effects of pyrantel pamoate, oxantel-pyrantel pamoate, levamisole and mebendazole in the treatment of intestinal nematodes

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

1 reference

7 January 2021

A field evaluation of benzimidazole and nonbenzimidazole drugs in a herd of dairy goats

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7 January 2021

Anthelmintic resistance in nematodes: extent, recent understanding and future directions for control and research

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7 January 2021

Strategic use of anthelmintics for parasitic nematodes in cattle and sheep

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7 January 2021

Mixtures of anthelmintics: a strategy against resistance

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7 January 2021

Anthelmintic resistance in the field: changes in resistance status of parasitic populations in response to anthelmintic treatment.

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7 January 2021

Photodecomposition of drugs

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7 January 2021

A Series of Compounds Active against Cestodes

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7 January 2021

Synthesis and anthelmintic activity of 4-alkoxy-1-naphthamidines

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7 January 2021

The anthelmintic efficacy of netobimin against experimental infections of Fasciola hepatica in sheep

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7 January 2021

Anthelmintic efficacy of netobimin against naturally acquired gastrointestinal nematodes in yearling heifers

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7 January 2021

Pharmacokinetic behaviour of netobimin and its metabolites in sheep

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7 January 2021

New Peripheral Antagonists of 5-Hydroxytryptamine

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7 January 2021

New bicyclic antidepressant agent. Synthesis and activity of napactadine and related compounds

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7 January 2021

2-Pyrrolidinylideneureas, a new class of central nervous system agents

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7 January 2021

Fluorinated aminoimidazolines. Synthesis and determination of tautomeric structure

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7 January 2021

Fluorinated aminoimidazolines. Reactivity of the nitrogen functions

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7 January 2021

The pharmacology and toxicology of midaflur

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7 January 2021

Effect of 5-imino-2,2,4,4-tetrakis (trifluoromethyl) imidazolidine (EXP 338) on spasticity: A quantitative evaluation

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7 January 2021

Synthesis and antidepressant properties of novel 2-substituted 4,5-dihydro-1H-imidazole derivatives.

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7 January 2021

Ciclazindol: An oral agent with weight reducing properties and hypoglycaemic activity

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7 January 2021

Comparison of the effects of chronic administration of ciclazindol and desipramine on pupillary responses to tyramine, methoxamine and pilocarpine in healthy volunteers

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7 January 2021

The effects of mazindol on local cerebral glucose utilization in rats.

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7 January 2021

Modified release tizanidine: a review

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7 January 2021

A new skeletal muscle relaxant (DS 103-282) compared to diazepam in the treatment of muscle spasm of local origin.

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7 January 2021

Actions of tizanidine on α1- and α2-adrenoceptors in the peripheral tissues

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7 January 2021

Tizanidine (DS103-282), a centrally acting muscle relaxant, selectively depresses excitation of feline dorsal horn neurones to noxious peripheral stimuli by an action at α2-adrenoceptors

1 reference

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7 January 2021

Selective antinociceptive effects of tizanidine (DS 103-282), a centrally acting muscle relaxant, on dorsal horn neurones in the feline spinal cord

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7 January 2021

Treatment of Tension-type Headache With Tizanidine Hydrochloride: Its Efficacy and Relationship to the Plasma MHPG Concentration

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7 January 2021

A multicentre placebo-controlled study in general practice to evaluate the efficacy and safety of tizanidine in acute low-back pain

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7 January 2021

Über in 11-Stellung amino-substituierte Dibenzo[b,f]-1, 4-thiazepine und -oxazepine. 9. Mitteilung über siebengliedrige Heterocyclen

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7 January 2021

Interaction of amoxapine with muscarinic cholinergic receptors: an in vitro assessment.

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7 January 2021

Amoxapine - An Antidepressant With Some Neuroleptic Properties?: A Review of Its Chemistry, Animal Pharmacology and Toxicology, Human Pharmacology, and Clinical Efficacy

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7 January 2021

11-Amino-5H-dibenzo[b, e]-1, 4-diazepine. 10. Mitteilung über siebengliedrige Heterocyclen

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7 January 2021

Clozapine. A review of its pharmacological properties, and therapeutic use in schizophrenia

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7 January 2021

Update on the clinical efficacy and side effects of clozapine

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7 January 2021

Intracisternal glycine activates the micturition reflex in urethane-anaesthetized rats.

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7 January 2021

Biochemical and pharmacological effects of fluperlapine on noradrenaline and acetylcholine systems in some rodent, bovine and crustacean preparations.

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7 January 2021

Differential effects of a new dibenzo-epine neuroleptic compared with haloperidol. Results of an open and crossover study.

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7 January 2021

Antipsychotic efficacy of fluperlapine. An open multicenter trial

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7 January 2021

Fluperlapine in tardive dyskinesia and parkinsonism

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7 January 2021

A new antitumor antibiotic, spergualin: Isolation and antitumor activity

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7 January 2021

Structure of an antitumor antibiotic, spergualin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

The total synthesis of spergualin, an antitumor antibiotic

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Synthesis of (-)-15-deoxyspergualin and (-)-spergualin-15-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Suppression of tissue graft rejection by spergualin.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Evidence that deoxyspergualin prevents sensitization and first-set cardiac xenograft rejection in rats by suppression of antibody formation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Deoxyspergualin directly suppresses antibody formation in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Synthesis and antitumor activity of dihydro-5-azacytidine, a hydrolytically stable analogue of 5-azacytidine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Contrasting Cytotoxicity Kinetics of 5-Azacytidine and Dihydro-5-azacytidine Hydrochloride in L1210 Leukemia in Mice2, 3

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Antitumor agents. 2. Bisguanylhydrazones of anthracene-9,10-dicarboxaldehydes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

STUDIES ON METHYLGLYOXAL BIS(GUANYLHYDRAZONE) ANALOGS. II. STRUCTURAL VARIATIONS ON METHYLGLYOXAL BIS(GUANYLHYDRAZONE)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Synthesis of methylglyoxalbis-guanylhydrazone-C14

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Pyrazine diuretics. II. N-amidino-3-amino-5-substituted 6-halopyrazinecarboxamides

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

PR 879-317A enhances in vitro immune activity of peripheral blood mononuclear cells from patients with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

The immunological profile of a new immunomodulatory agent, oxamisole

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Effect of oxamisole on immune parameters of mice infected with murine hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Inhibition of murine hepatitis virus infections by the immunomodulator 2,3,5,6,7,8-hexahydro-2-phenyl-8,8-dimethoxy-imidazo[1,2a]pyridine (PR-879-317A)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Pyrazine diuretics. VI. (Pyrazinecarboxamido)guanidines

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

New drug evaluations amiloride (Midamor, Merck, Sharp and Dohme)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Peptide Inhibition of the Prausnitz-Küstner Reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Gabexate as a therapy for disseminated intravascular coagulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

Biological roles of nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970378-3

7 January 2021

10.1016/S0079-6468(08)70378-3

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