(Q40624437)

22 September 2017

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title

H1-receptor antagonists. Comparative tolerability and safety (English)

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22 September 2017

F E Simons

1

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22 September 2017

1 May 1994

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22 September 2017

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22 September 2017

10

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22 September 2017

5

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22 September 2017

350-380

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Antihistamine- and decongestant-induced performance decrements.

22 September 2017

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12 December 2020

Astemizole. A nonsedating antihistamine with fast and sustained activity

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12 December 2020

Is there a difference in the affinity of histamine H1 receptor antagonists for CNS and peripheral receptors? An in vitro study.

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12 December 2020

Effects of diphenhydramine and alcohol on skills performance.

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12 December 2020

Mechanism of the cardiotoxic actions of terfenadine

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12 December 2020

Lack of pharmacodynamic and pharmacokinetic interactions of the antihistamine ebastine with ethanol in healthy subjects

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12 December 2020

Acute and subchronic effects of the H1-histamine receptor antagonist ebastine in 10, 20 and 30 mg dose, and triprolidine 10 mg on car driving performance

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12 December 2020

Incidence and toxicological aspects of drugs detected in 484 fatally injured drivers and pedestrians in Ontario

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12 December 2020

Clinical Features in Poisonings by Tricyclic Antidepressants with Special Reference to the ECG

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12 December 2020

Fixed drug eruption caused by diphenhydramine.

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12 December 2020

Benefit/risk ratio of the antihistamines (H1-receptor antagonists) terfenadine and chlorpheniramine in children

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12 December 2020

Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving

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12 December 2020

Histaminergic systems and sleep. Studies in man with H1 and H2 antagonists.

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12 December 2020

The effects of Benadryl and Hismanal on mood, physiological measures, antihistamine detection, and subjective symptoms

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12 December 2020

New H1-receptor antagonists: worth the price?

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12 December 2020

The effectiveness of diphenhydramine HCI in pediatric sleep disorders

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12 December 2020

Nervous reactions to terfenadine

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12 December 2020

Ebastine: the effect of a new antihistamine on psychomotor performance and autonomic responses in healthy subjects

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12 December 2020

Oral Facial Dyskinesia Associated with Prolonged Use of Antihistaminic Decongestants

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12 December 2020

Diphenhydramine-induced toxic psychosis.

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12 December 2020

Prospective study of the electrocardiographic effects of imipramine in children

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12 December 2020

The effect of diphenhydramine alone and in combination with ethanol on histamine skin response and mental performance

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12 December 2020

Diphenhydramine in insomniac family practice patients: a double-blind study.

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12 December 2020

Danger with benadryl of self medication and large dosage.

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12 December 2020

Schizophrenia-like psychosis following 'Mandrax' overdose

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12 December 2020

Receptor effects of cetirizine.

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12 December 2020

Studies on the central effects of the H1-antagonist, loratadine

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12 December 2020

Cleft lip repair using intramuscular hydroxyzine sedation and local anesthesia

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12 December 2020

Histamine H1-receptor in heart: unique electrophoretic mobility and autoradiographic localization

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12 December 2020

Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine

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12 December 2020

Dimenhydrinate dependence and withdrawal.

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12 December 2020

Generalized seizure due to terfenadine

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12 December 2020

The hypnotic effects of an antihistamine: promethazine

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12 December 2020

CNS Effects of the Antihistamines Diphenhydramine and Terfenadine (RMI 9918)

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12 December 2020

Effects of terfenadine, diphenhydramine, and placebo on skills performance

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12 December 2020

Astemizole-induced ventricular arrhythmias: an unexpected cause of convulsions

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12 December 2020

Effect of cyproheptadine on asthmatic children. Study of appetite, weight gain, and linear growth

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12 December 2020

Differences in performance impairment due to brompheniramine maleate as a function of the sustained-release system

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12 December 2020

Toxic Psychosis Due to Diphenhydramine Hydrochloride

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12 December 2020

Seasonal allergic rhinitis and antihistamine effects on children's learning.

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12 December 2020

Single and repeated dose comparison of three antihistamines and phenylpropanolamine: psychomotor performance and subjective appraisals of sleep

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12 December 2020

Antihistamines: impaired performance and the tendency to sleep.

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12 December 2020

Acute dystonia. An unusal reaction to diphenhydramine

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12 December 2020

The effects of acrivastine (BW825C), diphenhydramine and terfenadine in combination with alcohol on human CNS performance.

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12 December 2020

Torsades de pointes after terfenadine-itraconazole interaction

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12 December 2020

Absence of central effects with levocabastine eye drops

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12 December 2020

H1-receptor antagonists: clinical pharmacology and therapeutics

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12 December 2020

Lack of potentiation by cetirizine of alcohol-induced psychomotor disturbances

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12 December 2020

Safety of Therapy for Allergic Symptoms During Pregnancy

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12 December 2020

Letter: Chlorpheniramine-induced bone-marrow suppression

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12 December 2020

Diphenhydramine toxicity mimicking varicella encephalitis.

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12 December 2020

Topical diphenhydramine toxicity in a five year old with varicella

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12 December 2020

A comparison of antihistaminic and sedative effects of some H1-receptor antagonists

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12 December 2020

Astemizole-induced paresthesia

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12 December 2020

Comparative study of EEG effects of antihistamines in normal volunteers.

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12 December 2020

Effects of two antihistamine drugs on actual driving performance.

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12 December 2020

The acute effects of acrivastine (BW825C), a new antihistamine, compared with triprolidine on measures of central nervous system performance and subjective effects.

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12 December 2020

Probable Benadryl withdrawal manifestations in a newborn infant.

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12 December 2020

Prolonged Q-T interval following astemizole overdose

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12 December 2020

Controlled clinical investigation of trimeprazine as a sleep-inducer in normal subjects

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12 December 2020

Comparison between alprazolam and hydroxyzine for oral premedication.

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12 December 2020

Diphenhydramine hydrochloride intoxication

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12 December 2020

Sedative effects of antihistamines.

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12 December 2020

Peripheral antihistamine and central sedative effects of three H1-receptor antagonists

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12 December 2020

Azelastine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential

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12 December 2020

Letter: Facial dyskinesia related to antihistamine?

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12 December 2020

Lack of effects of astemizole on vestibular ocular reflex, motion sickness, and cognitive performance in man

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12 December 2020

An unusual case of cyproheptadine (Periactin) overdose in an adolescent female

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12 December 2020

Simulated assembly line performance following ingestion of cetirizine or hydroxyzine

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12 December 2020

QT prolongation and sudden cardiac death in patients with alcoholic liver disease

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12 December 2020

Toxic psychosis due to cyproheptadine in a child on hemodialysis: a case report

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12 December 2020

Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene

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12 December 2020

The pharmacokinetics and antihistaminic of the H1 receptor antagonist hydroxyzine

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12 December 2020

Pharmacokinetics of chlorpheniramine after intravenous and oral administration in normal adults.

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12 December 2020

Survival in complicated diphenhydramine overdose

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12 December 2020

Rated performance, cardiovascular and quantitative EEG parameters during simulated instrument flight under the effect of terfenadine

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12 December 2020

Antihistamines and reactivity

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12 December 2020

Agranulocytosis after antihistaminic therapy; report of a case following the prolonged use of tripelennamine (pyribenzamine) hydrochloride

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12 December 2020

Daytime Sleepiness and Antihistamines

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12 December 2020

Antihistamines and driving safety.

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12 December 2020

The pharmacokinetics and pharmacodynamics of hydroxyzine in patients with primary biliary cirrhosis

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12 December 2020

Effects of azatadine maleate on subjective appraisal and psychomotor functions relevant to driving performance

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12 December 2020

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12 December 2020

Performance studies with the H1-histamine receptor antagonists, astemizole and terfenadine

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12 December 2020

Transport of diphenhydramine in the central nervous system.

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12 December 2020

Astemizole-induced cardiac conduction disturbances in a child

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12 December 2020

The toxic effects of antihistaminic drugs

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12 December 2020

Effect of the antihistamines, brompheniramine maleate and triprolidine hydrochloride, on performance in man

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12 December 2020

Activated charcoal adsorption of diphenhydramine.

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12 December 2020

Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria

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12 December 2020

Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin

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12 December 2020

Evaluation of antihistamine-related daytime sleepiness. A double-blind, placebo-controlled study with terfenadine

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12 December 2020

The pharmacology and use of H1-receptor-antagonist drugs

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12 December 2020

SCH 434: a new antihistamine/decongestant for seasonal allergic rhinitis.

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12 December 2020

First-trimester drug use and congenital disorders

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12 December 2020

Chemically-induced chromosome changes in human cells in vitro

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12 December 2020

Effects of diphenhydramine in the fetal lamb after maternal or fetal administration.

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12 December 2020

Lack of effect of astemizole on ethanol dynamics or kinetics

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12 December 2020

The effect of fluconazole on the steady-state pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine in humans

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12 December 2020

Fixed drug eruption due to dimenhydrinate

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12 December 2020

Hydroxyzine hydrochloride: possible adverse cardiac interactions

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12 December 2020

Quantitative effects of cetirizine and diphenhydramine on mental performance measured using an automobile driving simulator.

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12 December 2020

Torsades de Pointes after treatment with terfenadine and ketoconazole

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12 December 2020

Antihistamines and visual function: studies on dynamic acuity and the pupillary response to light

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12 December 2020

Are over-the-counter sleep medications effective? All-night EEG studies

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12 December 2020

Immune thrombocytopenia due to antazoline (Antistina).

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12 December 2020

Terfenadine-induced tremor

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12 December 2020

PYRIBENZAMINE ACTIVATION OF THE ELECTROENCEPHALOGRAM.

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12 December 2020

A study of the anticholinergic activity of terfenadine in normal volunteers

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12 December 2020

Astemizole-Associated Urinary Retention

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12 December 2020

Skin reactions to terfenadine

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12 December 2020

Torsade de pointes associated with the use of intravenous haloperidol

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12 December 2020

The relative antihistaminic and psychomotor effects of hydroxyzine and cetirizine.

1 reference

12 December 2020

Levocabastine. A review of its pharmacological properties and therapeutic potential as a topical antihistamine in allergic rhinitis and conjunctivitis

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12 December 2020

The influence of antihistamines on human performance.

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12 December 2020

Effect of haemodialysis on the pharmacokinetics of cetirizine

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12 December 2020

Hallucinations and hyperthermia after promethazine ingestion

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12 December 2020

A Comparison of Central and Peripheral Effects of Cetirizine and Loratadine

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12 December 2020

Chronopharmacological study of antihistamines in man with special references to terfenadine

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12 December 2020

Generalised seizure due to terfenadine

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12 December 2020

Blockade of Na+ current by promethazine in guinea-pig ventricular myocytes

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12 December 2020

Effect of Promethazine Hydrochloride on Hand–Eye Co-ordination

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12 December 2020

Clinical evaluation of diphenhydramine hydrochloride for the treatment of insomnia in psychiatric patients: a double-blind study.

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12 December 2020

Cardiotoxic effect with convulsions in terfenadine overdose

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12 December 2020

Prolongation of simple and choice reaction times in a double-blind comparison of twice-daily hydroxyzine versus terfenadine

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12 December 2020

Pharmacokinetic and pharmacodynamic studies of the H1-receptor antagonist hydroxyzine in the elderly

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12 December 2020

EEG findings following intravenous injection of diphenhydramine hydrochloride (benadryl).

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12 December 2020

Relationship between occupation of cerebral H1-receptors and sedative properties of antihistamines. Assessment in the case of terfenadine

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12 December 2020

Effects of terfenadine and its metabolites on a delayed rectifier K+ channel cloned from human heart

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12 December 2020

Psychomotor effects of astemizole and chlorpheniramine, alone and in combination with alcohol.

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12 December 2020

Unusual treatment response of a severe dystonia to diphenhydramine

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12 December 2020

Correlation between EEG changes indicative of sedation and subjective responses

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12 December 2020

Effects of terfenadine and diphenhydramine alone or in combination with diazepam or alcohol on psychomotor performance and subjective feelings

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12 December 2020

Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.

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12 December 2020

Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine.

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12 December 2020

Giant U waves and associated ventricular tachycardia complicating astemizole overdose: Successful therapy with intravenous magnesium

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12 December 2020

Clinical symptomatology of diphenhydramine overdose: an evaluation of 136 cases in 1982 to 1985.

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12 December 2020

Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamine

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12 December 2020

Neonatal withdrawal syndrome associated with hydroxyzine hydrochloride

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12 December 2020

Effects of topical administration of levocabastine on psychomotor and cognitive function

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12 December 2020

Poisoning from dermal absorption of promethazine.

1 reference

12 December 2020

Dyskinesia Associated with Chronic Antihistamine Use

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12 December 2020

Prolongation of the Q-T interval and hyperkinetic ventricular arrhythmias probably induced by terfenadine use in liver cirrhosis patients

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12 December 2020

Prolonged QT interval and torsade de pointes following astemizole overdose

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12 December 2020

Asynchronies of diphenhydramine plasma-performance relationships.

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12 December 2020

Evaluation of sustained-action chlorpheniramine-pseudoephedrine dosage form in humans

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12 December 2020

Dystonic reactions to Dimotapp elixir

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12 December 2020

Peripheral antihistamine and central sedative effects of single and continuous oral doses of cetirizine and hydroxyzine

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12 December 2020

Massive diphenhydramine overdose resulting in death.

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12 December 2020

Correlation between plasma diphenhydramine level and sedative and antihistamine effects

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12 December 2020

Benadryl, a contributing cause of an accident.

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12 December 2020

Should promethazine in liquid form be available without prescription?

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12 December 2020

Evidence for tolerance to the central nervous effects of the histamine antagonist, triprolidine, in man

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12 December 2020

Double-blind comparison of cetirizine and placebo in the treatment of seasonal rhinitis

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12 December 2020

Phenothiazines and sudden infant death syndrome.

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12 December 2020

Torsade de pointes ventricular tachycardia associated with astemizole overdose

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12 December 2020

Loratadine produces antihistamine activity without adverse CNS, ECG or cardiovascular effects in guinea pigs. Comparative studies with terfenadine and sedating antihistamines

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12 December 2020

Differential cognitive effects of terfenadine and chlorpheniramine

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12 December 2020

Effects of altitude and two decongestant-antihistamine preparations on physiological functions and performance

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12 December 2020

Anemia following use of antihistaminic drugs.

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12 December 2020

Cardiac arrest in a young woman with the long QT syndrome and concomitant astemizole ingestion

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12 December 2020

The I antigen as an immune complex receptor in a case of haemolytic anaemia induced by an antihistaminic agent

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12 December 2020

The effects of phenindamine tartrate on sleepiness and psychomotor performance

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12 December 2020

Hydroxyzine intoxication in a 13-month-old child

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12 December 2020

Torsades de pointes occurring in association with terfenadine use

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12 December 2020

Dimenhydrinate: evidence for dependence and tolerance

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12 December 2020

Direct measurement of daytime sleepiness after administration of cetirizine and hydroxyzine with a standardized electroencephalographic assessment

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12 December 2020

Comparative safety of H1 antihistamines

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12 December 2020

Accidental astemizole overdose in young children

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12 December 2020

DIPHENHYDRAMINE POISONING TREATED BY EXCHANGE TRANSFUSION.

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12 December 2020

The pharmacodynamics of diphenhydramine-induced drowsiness and changes in mental performance

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12 December 2020

Torsades de pointes complicating treatment with terfenadine

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12 December 2020

Letter: Cleft palate and maternal diphenhydramine intake

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12 December 2020

Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders

1 reference

12 December 2020

Objective antihistamine side effects are mitigated by evening dosing of hydroxyzine

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12 December 2020

A comparison of triprolidine and clemastine on histamine antagonism and performance tests in man: Implications for the mechanism of drug induced drowsiness

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12 December 2020

Evaluation of the antimuscarinic activity of atropine, terfenadine and mequitazine in healthy volunteers

1 reference

12 December 2020

Loratadine-pseudoephedrine combination versus placebo in patients with seasonal allergic rhinitis

1 reference

12 December 2020

Diazepam effects on the performance of healthy subjects are not enhanced by treatment with the antihistamine ebastine

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12 December 2020

A placebo-controlled assessment of mequitazine and astemizole in tests of psychomotor ability.

1 reference

12 December 2020

Dyskinesia associated with amoxapine withdrawal and use of carbamazepine and antihistamines.

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12 December 2020

Central nervous system effects of meclizine and dimenhydrinate: evidence of acute tolerance to antihistamines

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12 December 2020

Drugs in pregnancy: effects on the fetus and newborn

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12 December 2020

Cyproheptadine and Growth

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12 December 2020

Sedative effects and plasma concentrations following single doses of triazolam, diphenhydramine, ethanol and placebo.

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12 December 2020

Urinary frequency in an adolescent female

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12 December 2020

Prenatal antihistamine exposure and retrolental fibroplasia

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12 December 2020

Torsade de pointes after astemizole overdose.

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12 December 2020

Performance studies with antihistamines

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12 December 2020

COMPARATIVE EFFECT OF THREE ANTIHISTAMINICS AND ETHANOL ON MENTAL AND MOTOR PERFORMANCE.

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12 December 2020

Some clinical pharmacological studies with terfenadine, a new antihistamine drug

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12 December 2020

Cardiotoxic effects of astemizole overdose in children

1 reference

12 December 2020

Paranoid psychosis after abuse of Actifed

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12 December 2020

The interaction between ethanol and antihistamines: 2. Clemastine

1 reference

12 December 2020

Central anticholinergic syndrome in a child: a case report

1 reference

12 December 2020

Doxepin-induced cardiac dysrhythmia.

1 reference

12 December 2020

In vitro and in vivo binding characteristics of a new long-acting histamine H1 antagonist, astemizole

1 reference

12 December 2020

Cardiovascular effects of therapeutic doses of tricyclic antidepressants. A review

1 reference

12 December 2020

Effect of diphenhydramine on subjective sleep parameters and on motor activity during bedtime.

1 reference

12 December 2020

Antihistamines and highway safety

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12 December 2020

Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability

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12 December 2020

Effects on the human central nervous system of two isomers of ephedrine and triprolidine, and their interaction

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12 December 2020

Acute ketotifen overdosage. A review of present clinical experience

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12 December 2020

Effects of allergy season on mood and cognitive function.

1 reference

12 December 2020

The effects of terfenadine with and without alcohol on an aspect of car driving performance.

1 reference

12 December 2020

Torsade de pointes induced by astemizole in a patient with prolongation of the QT interval

1 reference

12 December 2020

An unusual case of antihistamine intoxication

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12 December 2020

Accidental childhood death from diphenhydramine overdosage.

1 reference

12 December 2020

Teratogenic effect of buclizine and hydroxyzine in the rat and chlorcyclizine in the mouse

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12 December 2020

Toxic encephalopathy caused by topically applied diphenhydramine

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12 December 2020

Comparison of the central and peripheral effects of cetirizine and terfenadine

1 reference

12 December 2020

Monoamine oxidase inhibitors and tricyclic antidepressants: comparison of their cardiovascular effects

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12 December 2020

Topically induced diphenhydramine toxicity

1 reference

12 December 2020

Haloperidol-induced torsades de pointes

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12 December 2020

Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences

1 reference

12 December 2020

Astemizole-induced torsade de pointes

1 reference

12 December 2020

Physostigmine Reversal of Antihistamine-induced Excitement and Depression

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12 December 2020

Prolonged cholestasis after cyproheptadine-induced acute hepatitis.

1 reference

12 December 2020

Placental transfer of diphenhydramine in chronically instrumented pregnant sheep.

1 reference

12 December 2020

The toxicity of benadryl; report of a case and review of the literature

1 reference

12 December 2020

A repeated dose comparison of the side effects of five antihistamines on objective assessments of psychomotor performance, central nervous system arousal and subjective appraisals of sleep and early morning behaviour

1 reference

12 December 2020

Contact dermatitis caused by diphenhydramine hydrochloride

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12 December 2020

Effect of concomitant administration of cimetidine and ranitidine on the pharmacokinetics and electrocardiographic effects of terfenadine

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12 December 2020

Plasma concentrations of astemizole in patients with terminal renal insufficiency, before, during and after hemodialysis

1 reference

12 December 2020

10.2165/00002018-199410050-00002

Identifiers

DOI

0 references

PubMed ID

7913608

1 reference

PubMed ID

7913608